Diabetic Neuropathy News and Research

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Diabetic neuropathy is a peripheral nerve disorder caused by diabetes or poor blood sugar control. The most common types of diabetic neuropathy result in problems with sensation in the feet. It can develop slowly after many years of diabetes or may occur early in the disease. The symptoms are numbness, pain, or tingling in the feet or lower legs. The pain can be intense and require treatment to relieve the discomfort. The loss of sensation in the feet may also increase the possibility that foot injuries will go unnoticed and develop into ulcers or lesions that become infected. In some cases, diabetic neuropathy can be associated with difficulty walking and some weakness in the foot muscles. There are other types of diabetic-related neuropathies that affect specific parts of the body. For example, diabetic amyotrophy causes pain, weakness and wasting of the thigh muscles, or cranial nerve infarcts that may result in double vision, a drooping eyelid, or dizziness. Diabetes can also affect the autonomic nerves that control blood pressure, the digestive tract, bladder function, and sexual organs. Problems with the autonomic nerves may cause lightheadedness, indigestion, diarrhea or constipation, difficulty with bladder control, and impotence.

Cultured cells from the bone marrow can heal nerves in diabetes model

Transplanting cells that replenish blood vessels can also restore nerve function in an animal model of diabetic neuropathy, Emory researchers have found.

5 Feb 2009

Leconotide, an investigative calcium channel blocker, shows potential as pain treatment

Results of a pre-clinical study of leconotide, an investigative calcium channel blocker, shows it has the potential to be safe, selective, and efficacious as a new non-opioid treatment for pain relief. It also holds promise in multiple drug delivery options including nasal spray, transdermal patch, and pills. Data were presented today at the American Academy of Pain Medicine's 25th Annual Meeting.

29 Jan 2009

XTL Biopharmaceuticals announces results from Bicifadine in diabetic neuropathic pain trial

XTL Biopharmaceuticals Ltd. has announced the top-line results from the Bicifadine Phase 2b clinical trial for the treatment of diabetic neuropathic pain.

19 Nov 2008

Diabetes and foot problems

Bradford Miller has had diabetes for nine years, and he knows the importance of quick treatment for related problems such as swelling and numbness in the feet.

11 Nov 2008

UT Southwestern launches study of surgical option for treating diabetic and other neuropathies

UT Southwestern Medical Center plastic surgeons and specialists in diabetes, neurology, pain management and rehabilitation are launching a cutting-edge study of peripheral nerve surgery to alleviate long-standing pain and numbness in patients with diabetic neuropathy.

10 Jul 2008

Diabetic neuropathy costs $3.65 billion per year in health-related lost productive time

Workers who have diabetes with neuropathic symptoms such as numbness or tingling in feet or hands lose the equivalent of 1.4 hours a week or $3.65 billion per year in health-related lost productive time, a recent study finds.

8 Oct 2007

Green light for first drug to treat fibromyalgia

Authorities in the United States have given approval for the first drug to treat the condition fibromyalgia.

25 Jun 2007

U.S. FDA approves Lyrica (pregabalin), the first drug to treat fibromyalgia

The U.S. Food and Drug Administration has approved Lyrica (pregabalin), the first drug to treat fibromyalgia, a disorder characterized by pain, fatigue and sleep problems.

23 Jun 2007

Sangamo BioSciences starts phase 2 trial of therapy diabetic neuropathy

Sangamo BioSciences has announced that the company has initiated a repeat-dosing, multi-center Phase 2 clinical trial of SB-509 in subjects with moderate to severe diabetic peripheral sensory motor neuropathy (DN).

27 Apr 2007

Single master gene crucial for nerve cell insulation

Researchers funded by the National Institutes of Health have discovered how a defect in a single master gene disrupts the process by which several genes interact to create myelin, a fatty coating that covers nerve cells and increases the speed and reliability of their electrical signals.

17 Apr 2007

Potentially ground-breaking treatment for nerve damage caused by diabetes

The University of Manchester team has discovered that injection of a novel therapeutic that works by stimulating a person's genes may prevent nerve damage - primarily to the hands and feet - caused by the disease.

From The University of Manchester 8 Jun 2006

Novel research points to promising relief target for chronic pain

By some accounts, chronic pain affects nearly 100 million Americans from such varied causes as arthritis, sciatica, cancer, diabetes. Most forms of pain result from identifiable causes which serve the "good" purpose in warning of a real physical problem that needs attention, or rest.

6 Jun 2006

Potential new treatment for diabetic nerve damage

A potentially ground-breaking treatment for nerve damage caused by diabetes has shown promising results in preclinical and early patient trials.

From The University of Manchester 6 Jun 2006

Malfunctioning bone marrow cells cause neuropathy in many people with diabetes

Malfunctioning bone marrow cells that produce insulin appear to cause a dangerous nerve condition called neuropathy that disables many people with diabetes, said a research team led by Baylor College of Medicine (BCM) in Houston.

22 Aug 2005

Potential new treatment for nerve damage caused by diabetes

Research into a new treatment for nerve damage caused by diabetes could bring relief to millions of diabetic patients, say experts.

From The University of Manchester 26 Jul 2005

"Ipod-like" device to help correct balance disorders

Researchers at Oregon Health & Science University's Neurological Sciences Institute and the University of Bologna have developed a portable "Ipod-like" device that can be used to help correct balance disorders. Scientists believe this new device, based on auditory feedback of balance, can be worn on the belt like a pager to provide regular therapy for patients with balance disorders, improving their day-to-day activities.

13 Jul 2005

Venom of marine cone snails may provide an improved treatment for neuropathic pain associated with diabetes

A cone snail toxin discovered by Melbourne researchers has proven to have great potential for easing pain and could provide an improved treatment for neuropathic pain associated with diabetes.

12 Jun 2005

Survey finds most people with diabetes don't know about highly prevalent, serious complication

A new national survey commissioned by the American Diabetes Association (ADA) reveals that, while the majority of people with diabetes experience symptoms associated with diabetic neuropathy (nerve damage) - a serious complication of diabetes that leads to sensations of pain and/or numbness, tingling or "pins and needles" in the feet and hands - only a small minority have been diagnosed with this condition.

10 May 2005

Chronic pain treatments more effective when taken together

People suffering from chronic, debilitating pain caused by nerve damage or disease report better pain relief at lower doses of a combined drug treatment than from either drug administered individually, a new Queen’s study funded by the Canadian Institutes of Health Research (CIHR) shows.

3 Apr 2005

Neuren and Metabolic collaborate to develop range of nerve repair compounds

Neuren Pharmaceuticals Ltd (Neuren) and Metabolic Pharmaceuticals Ltd (Metabolic) have announced that the two companies have agreed to collaborate to co-develop Neuren's class of Neuro-regenerative Peptides (NRPs) for the treatment of degenerative conditions such as peripheral neuropathy, motor neuron disease and repairing the brain or nerves after injuries such as spinal cord injury.

7 Mar 2005