Diphtheria News and Research

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Diphtheria is a disease caused by a bacterium, Corynebacterium diphtheriae, that usually affects the tonsils, throat, nose and/or skin. It is passed from person to person by droplet transmission, usually by breathing in diphtheria bacteria after an infected person has coughed or sneezed. Although diphtheria disease is rare in the U.S., it appears that C diphtheriae continues to circulate in areas of the country with previously endemic diphtheria. Diphtheria also occurs in many other parts of the world.

Scientists establish a goal of creating vaccine gene chip to speed up vaccine testing

Testing the efficacy of vaccines in clinical trials takes years, even decades. Yet challenging infections like HIV, malaria and dengue are striking today. To speed up vaccine testing, scientists at the Emory Vaccine Center have established a goal of creating a "vaccine gene chip."

17 Dec 2013

MassBiologics gets FDA orphan drug designation for MBL-HCV1 antibody

MassBiologics of the University of Massachusetts Medical School has received an orphan drug designation from the U.S. Food and Drug Administration for MBL-HCV1, a monoclonal antibody developed to prevent hepatitis C virus recurrence in patients receiving a liver transplant.

5 Dec 2013

European Commission approves updated label of Prevenar 13 for high risk pneumococcal disease

Pfizer Inc. (NYSE:PFE) announced today that the European Commission approved updates to the Summary of Product Characteristics (SmPC) for the company's pneumococcal conjugate vaccine Prevenar 13* (pneumococcal polysaccharide conjugate vaccine [13-valent, adsorbed]), regarding its use in certain populations at high risk of pneumococcal disease.

18 Oct 2013

Abortion of female fetuses in northern India results in gender imbalance

Modern ultrasound technology and economic pressure leads to female fetuses in the Ballabgarh area of northern India being aborted more often than male fetuses. Additionally, girls up to the age of five die more frequently than boys, which results in a gender imbalance in the area, according to Anand Krishnan, MD and doctoral candidate at Ume- University, who defends his thesis on 11 October.

9 Oct 2013

New report shows 6.6 million children under 5 died in 2012

In 2012, approximately 6.6 million children worldwide - 18 000 children per day - died before reaching their fifth birthday, according to a new report released today by UNICEF, WHO, the World Bank Group and the United Nations Department of Economic and Social Affairs/Population Division. This is roughly half the number of under-fives who died in 1990, when more than 12 million children died.

13 Sep 2013

Health care providers are missing opportunities to improve teens' vaccination coverage

Health care providers are missing opportunities to improve teens' vaccination coverage, reports a new study in the Journal of Adolescent Health.

2 Aug 2013

Pfizer's Prevenar 13 receives European approval to include adults for prevention of invasive disease

Pfizer Inc. announced today the company's pneumococcal conjugate vaccine, Prevenar 13 (pneumococcal polysaccharide conjugate vaccine [13-valent, adsorbed]), received European approval for an expanded indication to include adults aged 18 to 49 years for active immunization for the prevention of invasive disease caused by vaccine-type Streptococcus pneumoniae (S. pneumoniae).

10 Jul 2013

Report highlights successes in improving maternal health, reducing child mortality

Rapid expansion of programs to prevent HIV transmission to babies and vaccinate children show how results can be achieved in relatively little time.

1 Jun 2013

Somalia launches pentavalent vaccine with support from GAVI, UNICEF, WHO

"Coinciding with World Immunization Week, the Somali government announced on 24 April its intention to vaccinate all children under the age of one with a new five-in-one vaccine, known as a pentavalent vaccine, funded by the GAVI Alliance, with [UNICEF] and the [WHO] as implementing partners," IRIN reports.

30 Apr 2013

Pfizer reports that Prevenar 13 Phase 3 study meets all primary, secondary objectives

Pfizer Inc. presented today the results from a Phase 3 study investigating immunogenicity, tolerability and safety of Prevenar 13 (Pneumococcal polysaccharide conjugate vaccine [13-valent, adsorbed]) in adults 18 to 49 years of age.

From Pfizer, Inc. 29 Apr 2013

Indian drug supplier cuts price of 5-in-1 childhood vaccine for GAVI Alliance; Groups highlight World Immunization Week

"The cost of immunizing children in developing countries with a five-in-one vaccine is set to fall after a deal by an Indian supplier to slash the price it charges the GAVI global vaccines group," Reuters reports.

19 Apr 2013

Global experts highlight strategies to immunize more children

In advance of World Immunization Week, global experts are highlighting strategies to further advance progress on the Global Vaccine Action Plan that was endorsed by the World Health Assembly, 2012.

19 Apr 2013

National Jewish Health researchers unravel mystery of adjuvants

Aluminum salts, or alum, have been injected into billions of people as an adjuvant to make vaccines more effective.

8 Apr 2013

2 in 5 parents believe HPV vaccine is unnecessary

A rising percentage of parents say they won't have their teen daughters vaccinated to protect against the human papilloma virus, even though physicians are increasingly recommending adolescent vaccinations, a study by Mayo Clinic and others shows.

18 Mar 2013

UCSF study on T-cell behavior sheds light on how vaccines work

The immune system's T cells, while coordinating responses to diseases and vaccines, act like honey bees sharing information about the best honey sources, according to a new study by scientists at UC San Francisco.

14 Mar 2013

Results from Pfizer’s Prevnar 13 Phase 3 study on HIV

Pfizer Inc. presented today the results from a Phase 3 study demonstrating the immunogenicity, tolerability and safety of Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine Diphtheria CRM197 Protein)in adults infected with human immunodeficiency virus (HIV).

5 Mar 2013

India needs political leadership, resources to ensure children's right to health

"India is making positive strides in reducing child mortality through new policies and ambitious programs, but preventing the deaths of millions of children remains one of the country's greatest challenges," health expert and blogger John Butler writes in the Wall Street Journals "India Real Time" blog, noting, "Roughly 1.7 million children under five years old die every year in India, says UNICEF, representing more than a fifth of all child deaths worldwide."

2 Mar 2013

CDC: Adult vaccination rates 'unacceptably low'

According to the CDC, a "substantial increase" in immunizations for adults is necessary.

31 Jan 2013

Common myths about flu from Mayo Clinic

It seems you can't go anywhere these days without hearing "the flu this" or "the flu that." Unfortunately, this season's influenza outbreak is one of the worst in years. And it's not just the flu virus that's causing problems; there are also many myths about the flu that are keeping people from doing more to prevent it.

29 Jan 2013

FDA approves Pfizer’s Prevnar 13 to prevent pneumococcal disease in older children, adolescents

Pfizer Inc. announced today that the U.S. Food and Drug Administration (FDA) has granted approval for the expansion of the company's pneumococcal conjugate vaccine, Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]), for use in older children and adolescents aged 6 years through 17 years for active immunization for the prevention of invasive disease caused by the 13 Streptococcus pneumoniae serotypes contained in the vaccine.

28 Jan 2013