Down’s Syndrome News and Research

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Genetic mutations and cellular modifications may provide clues to the associations between slight genetic abnormalities and often fatal diseases

Modern research is delving deep into the human genome to find the answers to medical mysteries and, hopefully, cures for the most deadly diseases. According to four new studies presented during the 46th Annual Meeting of the American Society of Hematology

5 Dec 2004

Researchers step closer to cure for common childhood cancer

Acute lymphoblastic leukemia (ALL) is a malignant disease caused by the abnormal growth and development of white blood cells (WBC) in the bone marrow and blood. ALL is the most common cancer occurring in children with an annual rate of approximately 30 to 40 new cases per million.

5 Dec 2004

Overexpression of a protein called Down Syndrome Critical Region 1 (DSCR-1) reduces tumor growth

Scientists have found that overexpression of a protein called Down Syndrome Critical Region 1 (DSCR-1) blocks the formation of new blood vessels and thus reduces tumor growth. Therapeutics based on this finding may potentially lead to new cancer treatments.

19 Nov 2004

Study is the first to show that lowering the levels of lipid in nerve terminals affects the efficiency of neurotransmission

Yale researchers demonstrate the crucial role of a membrane lipid called phosphatidylinositol-4,5-bisphosphate (PtdIns (4,5)P2) in the communication of information between synapses in the brain, according to a study published this week in Nature.

26 Sep 2004

Having an infant in poor health decreases the chances a couple living together 12 to 18 months later

A study of mainly unwed, U.S. urban parents finds that fathers of infants in poor health are less likely to be living with the child's mother following the child's first birthday than fathers of healthy children.

23 Sep 2004

Spina bifida on the decline in Australia

The number of babies with spina bifida or similar abnormalities has declined by over 40 per cent since 1995, Australia's Minister for Health, Bronwyn Pike, said yesterday.

15 Sep 2004

Study tests inflammatory response of Down Syndrome patients

Almost all people with Down syndrome have periodontal disease, and a Medical College of Georgia dentist suspects that an abnormal inflammatory response is the culprit.

13 Sep 2004

Gene responsible for the onset of aging

Mayo Clinic researchers have discovered a gene responsible for the onset of aging, including age-related disorders such as infertility, reproductive problems and cataracts.

7 Jul 2004

£18m to upgrade genetic laboratories in England

Six areas in England are to receive a share of £18m to upgrade genetic laboratories and help patients get genetic test results quicker.

5 Jul 2004

Current legislation on preimplantation genetic diagnosis in Germany does not reflect the views of the general public

At present PGD is forbidden in Germany, but in one of the first large study of attitudes to PGD amongst the general population and infertile couples in Germany, the researchers found that the majority of Germans think the technique should be permitted.

28 Jun 2004

Cellular garbage plays a key role in the process of cytokinesis, or cell division

A cellular structure discovered 125 years ago and dismissed by many biologists as "cellular garbage" has been found to play a key role in the process of cytokinesis, or cell division, one of the most ancient and important of all biological phenomena.

27 May 2004

Obese women more likely to have pregnancy complications and caesarean sections than women of average weight

The controlled study is one of the largest ever to look at obesity in pregnancy, following more than 16,000 pregnant women at 14 medical centers across the country.

20 May 2004

New patent has potential for the treatment of obesity

Two researchers have announced receipt of a patent on the use of MSH analogs--chemicals that regulate fat storage and metabolism in the body.

11 May 2004

NBC's Friends stars present $1 million donation to American Red Cross

On the set of Friends, Target Stores presented a $1 million donation to Marsha J. Evans, President and CEO of the American Red Cross, in celebration of the Friends series finale on May 6.

5 May 2004

New screening helps to determine risk for having a baby with Down syndrome

Obstetricians at Thomas Jefferson University Hospital, Philadelphia, are offering a new, quicker, option for pregnant women who choose to undergo first trimester screening. The screening helps to determine whether the woman is at increased risk for having a baby with Down syndrome.

5 May 2004

A new book to help children with Down Syndrome develop lifelong motor skills

A new book providing practical suggestions on how parents and professionals can help children with Down Syndrome (DS) develop lifelong motor skills will be published later this month.

3 May 2004

New information on genetic shuffling before egg or sperm formation rewrites genetic theory

Key decisions in the genetic shuffling that occurs before eggs or sperm are formed are made earlier than thought, rewriting textbook genetics, according to recent papers from researchers at UC Davis, Harvard University and UC San Diego.

16 Apr 2004

NZ Research helps difficult pregnancies

Before the 1960's knowledge of the intrauterine environment was like a black box, limiting clinical understanding, and monitoring of the fetus during pregnancy. Little was known about the fetus until after birth happened. Now that has changed dramatically, and there have been revolutionary advances, particularly in the last 20 years enabling clinicians to diagnose and treat problems which develop in the womb.

13 Apr 2004