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Promising candidate medication for preventing and reversing fentanyl-induced overdose

Researchers assessed CSX-1004, a monoclonal antibody (mAb), for its efficacy in reversing fentanyl overdose based on its high affinity for fentanyl, positive animal model results, and safe pharmacokinetic profile, positioning it as a potential solution in the opioid crisis.

7 Dec 2023

Cannabis and alcohol co-use disrupts brain development and impairs memory

The increased legalization of cannabis over the past several years can potentially increase its co-use with alcohol. Concerningly, very few studies have looked at the effects of these two drugs when used in combination.

30 Nov 2023

More than half of low-income unmarried couples have positive co-parenting relationships

Despite the many challenges they face, slightly more than half of unmarried low-income couples with children have positive co-parenting relationships, a new study found.

27 Nov 2023

Oral nicotine pouches fail to satisfy cravings of current smokers

Oral nicotine pouches, a tobacco-leaf-free product marketed as an alternative to cigarettes, do little to curb current smokers' nicotine cravings, according to a new study.

15 Nov 2023

COVID-19 pandemic slowed progress toward ending HIV epidemic in the U.S.

The COVID-19 pandemic slowed previous gains made in controlling HIV blood levels and worsened health disparities, according to UC Francisco researchers leading the largest U.S. evaluation of the impact of the public health crisis on people with HIV.

14 Nov 2023

Researchers identify predictive brain imaging-based biomarkers of mental illness in adolescents

Research and treatment of psychiatric disorders are stymied by a lack of biomarkers - objective biological or physiological markers that can help diagnose, track, predict, and treat diseases.

9 Nov 2023

NIH awards $2.1 million to UCLA to end the HIV epidemic

The National Institutes of Health (NIH) has granted $2.1 million to UCLA's Center for HIV Identification, Prevention, and Treatment Services (CHIPTS) and the UCLA-CDU Center for AIDS Research (CFAR) to support four research projects and an implementation science consultation hub.

2 Nov 2023

E-cigarette flavor restrictions may increase cigarette sales, study finds

The immense popularity of electronic cigarettes, or e-cigarettes, among young people has led many policymakers to restrict the sale of flavored varieties.

18 Oct 2023

Telehealth may improve access and retention for opioid use disorder treatment

Starting buprenorphine treatment for opioid use disorder through telehealth was associated with an increased likelihood of staying in treatment longer compared to starting treatment in a non-telehealth setting, according to a new study analyzing Medicaid data from 2019-2020 in Kentucky and Ohio.

18 Oct 2023

University of Kentucky selected as the nationwide coordination center for NIH racial equity initiative

The University of Kentucky has been selected as the nationwide coordination center for a National Institutes of Health (NIH) initiative. Danelle Stevens-Watkins, Ph.D., will lead the National Institute on Drug Abuse (NIDA) Racial Equity Initiative as principal investigator.

13 Oct 2023

Syphilis rates twice as high among transgender women and Black gay and bisexual men in Chicago

Transgender women and Black gay and bisexual men in Chicago are nearly twice as likely to contract syphilis at some point in their lives as white gay men, according to a new study conducted by scientists at Northwestern University.

10 Oct 2023

Drug overdose deaths disproportionately affect Americans without college education

Drug overdose deaths increased sharply among Americans without a college education and nearly doubled over a three-year period among those who don't have a high school diploma, according to a new RAND Corporation study.

6 Oct 2023

Study can improve understanding of what causes Sudden Unexpected Death in Epilepsy

New findings may take scientists a step closer to understanding what causes SUDEP-;Sudden Unexpected Death in Epilepsy-;a rare but fatal complication of epilepsy.

3 Oct 2023

Officials agree: Use settlement funds to curb youth addiction. But the ‘how’ gets hairy.

When three teenagers died of fentanyl overdoses last year in Larimer County, Colorado, it shocked the community and “flipped families upside down,” said Tom Gonzales, the county’s public health director.

25 Sep 2023

Social adversity and stress leave distinct signatures on mom and baby gut health

Researchers evaluate the effect of social disadvantages and psychological stressors on the gut microbiome of mothers and their infants.

24 Sep 2023

New brain biomarker predicts recovery from treatment-resistant depression

Using a novel deep brain stimulation (DBS) device capable of recording brain signals, researchers have identified a pattern of brain activity or "biomarker" related to clinical signs of recovery from treatment-resistant depression.

20 Sep 2023

New study suggests higher buprenorphine doses could help save lives

Individuals with opioid use disorder who were prescribed a lower buprenorphine dose were 20% more likely to discontinue treatment than those on a higher dose, according to a study of patients prescribed buprenorphine in Rhode Island from 2016 to 2020, as fentanyl became widely available.

19 Sep 2023