Drug Delivery News and Research

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Drug delivery is a term that refers to the delivery of a pharmaceutical compound into the body. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Much research is now focussing on nanotechnology as a drug delivery method.

How human cell atlases provide the missing links between genes, diseases and therapies

A Nature Medicine journal perspective article describes the potential of cell atlases in shaping the future of medicine. Providing the missing link between genes and diseases, single-cell atlases make it possible to develop more precise and specific diagnostic tools by understanding the mechanisms of complex diseases.

12 Dec 2022

Biobattery researchers have a solution for the hard-to-reach small intestine

Tech companies have developed many devices that work outside the body, such as cell phones, smart watches, tablets and hundreds of others. Inside the body, though? That's obviously trickier for several reasons, but power for a device is a big one.

12 Dec 2022

Using cationic nanonmaterials to target visceral adiposity

Researchers have long been working on how to treat obesity, a serious condition that can lead to hypertension, diabetes, chronic inflammation, and cardiovascular diseases.

1 Dec 2022

Aptamer Group opens new facilities to meet the increasing demand for Optimer technology

Aptamer Group plc, the developer of novel Optimer® binders to enable innovation in the life sciences industry, announces that it has opened its new facilities in York Science Park, UK, that will enable it to meet the increasing demand for Optimer technology.

From Aptamer Group 30 Nov 2022

Sartorius BIA Separations and Exopharm Sign Joint Research Agreement to Develop Integrated Technology

Sartorius BIA Separations (BIA), a leading bio-chromatography company, now part of the international life science group Sartorius, and Exopharm Ltd. (ASX:EX1), a company at the forefront of transformative medicines using exosomes, or extracellular vesicles (EVs), today announced they had entered into a formal collaboration.

From Sartorius 23 Nov 2022

Pt(IV)-conjugated drug-delivery system shows efficacy in glioblastoma therapy

A recent study demonstrated a novel method for delivering anti-cancer drugs, conjugated to modified cell-penetrating peptides across the blood-brain barrier, in mice to treat glioblastoma.

18 Nov 2022

Researchers explore the role of trigeminal axons in nose-to-brain delivery of antidepressant

Intranasal (in.) administration has been garnering increasing popularity as a non-invasive approach to deliver drugs directly to the brain. This approach involves the respiratory or olfactory epithelia of the nasal mucosa through which the drugs reach the central nervous system (CNS).

11 Nov 2022

IVI and Lemonex sign MOU to join forces on vaccine development

The International Vaccine Institute announced on November 10 it signed a memorandum of understanding (MOU) with Lemonex, a company specializing in RNA gene therapy development, and agreed to seek cooperation in research and development.

10 Nov 2022

Researchers use lasso-grafting for designing receptor agonists with enhanced pharmacokinetics

Cell growth and repair are stimulated by biomolecules known as cytokines and growth factors. Unfortunately, delivering adequate concentrations of these molecules to the brain for treating neurological conditions like Alzheimer's disease is challenging as they are either cleared out of the blood very quickly or do not penetrate neural tissue effectively.

8 Nov 2022

Terasaki Innovation Summit to focus on improving technological, entrepreneurial translation of personalized medicines

The Terasaki Institute for Biomedical Innovation (TIBI) will be hosting the Terasaki Innovation Summit on March 8-10, 2023, at the UCLA Meyer & Renee Luskin Center in Los Angeles.

8 Nov 2022

New nanovaccine greatly improves cytokine production

Cancer immunotherapies, such as immune checkpoint inhibition therapy, have been attracting attention in recent years as new methods for treating cancer. However, immune checkpoint inhibition therapy is only effective in 20%–30% of cancer patients, so developing better drug delivery systems to induce anticancer cellular immunity is necessary.

1 Nov 2022

Novel nanotechnology triggers potent therapeutic anti-tumor immune responses against multiple cancers

A Ludwig Cancer Research study has developed a novel nanotechnology that triggers potent therapeutic anti-tumor immune responses and demonstrated its efficacy in mouse models of multiple cancers.

28 Oct 2022

OSU researchers take major step toward improving, lengthening the lives of cystic fibrosis patients

Researchers at Oregon State University and Oregon Health & Science University have taken a key step toward improving and lengthening the lives of cystic fibrosis patients, who experience chronically clogged airways and a dramatically shortened life expectancy.

27 Oct 2022

Study develops a strategy to noninvasively track tumor-associated macrophages

A Ludwig Cancer Research study has developed a strategy to noninvasively track immune cells known as macrophages within brain and breast tumors in living mice.

19 Oct 2022

Advances in nasal delivery of antibiotics

In a recent study published in the Journal of Drug Delivery Science and Technology, researchers reviewed the advances and challenges in the intranasal delivery of antibiotics.

17 Oct 2022

Transition in the management of COVID-19

A review of the current approaches to managing COVID-19, including diagnostic, therapeutic, and preventive measures.

16 Oct 2022

$1.91 million grant to explore human internal "clock” as a tool for optimizing tissue regeneration

The human internal "clock" responsible for regulating sleep cycles and many other biological functions will be explored as a tool for optimizing tissue regeneration under a $1.91 million grant University of Massachusetts Amherst biomedical engineer and assistant professor Cathal Kearney has received from the National Institutes of Health's National Institute of General Medical Sciences.

13 Oct 2022

Rescue Biomedical receives SBIR grant to develop opioid overdose detection and response technology

Rescue Biomedical has received a Fast-Track Small Business Innovation Research, or SBIR grant from the National Institutes of Health to develop its technology that detects when a person is overdosing on an opioid and delivers naloxone to reverse the action.

7 Oct 2022

Researchers develop new bandage treatment to treat diabetic foot ulcers

Researchers at Queen's University Belfast have designed a new bandage treatment, known as a scaffold, to treat diabetic foot ulcers, which is cost-effective while improving patient outcomes.

6 Oct 2022

New capsule tunnels through mucus in the GI tract to deliver large protein drugs

One reason that it's so difficult to deliver large protein drugs orally is that these drugs can't pass through the mucus barrier that lines the digestive tract.

28 Sep 2022