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New research finds 74% drop in myocardial infarction over 20-year period

Better control of cholesterol levels and blood pressure and a decline in smoking have contributed to a 74% drop in the risk of heart attack among nearly 10,000 civil servants working in London over a 20-year period, according to new research.

9 Jun 2011

Children who experience trauma more likely to have behavior and learning problems

New research has shown that children's risk for learning and behavior problems and obesity rises in correlation to their level of trauma exposure, says the psychiatrist at the Stanford University School of Medicine and Lucile Packard Children's Hospital who oversaw the study.

9 Jun 2011

FDA accepts Adamis IND for APC-100 to treat prostate cancer

Adamis Pharmaceuticals Corporation announced today that the FDA has accepted an Investigational New Drug (IND) application for APC-100 to treat prostate cancer (PCa).

9 Jun 2011

Hepatitis C virus (HCV)-associated liver disease after liver transplantation

Hepatitis C virus (HCV)-associated liver disease continues to be the most common indication for liver transplantation (LT) in the United States accounting for nearly 50% of all liver transplants. Recurrence is universal in patients viremic at the time of transplantation with histological hepatitis developing in the majority of patients. Although the natural history of recurrent HCV is difficult to predict, it is widely accepted that cirrhosis from recurrent HCV occurs in up to 30% of patients within five years of transplantation.

8 Jun 2011

Childhood trauma linked to higher rates of mental health problems and obesity, says Stanford/Packard psychiatrist

New research has shown that children’s risk for learning and behavior problems and obesity rises in correlation to their level of trauma exposure, says the psychiatrist at the Stanford University School of Medicine and Lucile Packard Children’s Hospital who oversaw the study. The findings could encourage physicians to consider diagnosing post-traumatic stress disorder rather than attention deficit/hyperactivity disorder, which has similar symptoms to PTSD but very different treatment.

8 Jun 2011

Therapeutic equivalent to replace penicillin

Antibiotics are among the greatest achievements of medical science. But lately the former multi-purpose weapon fails in the battle against infectious diseases. Bacteria are increasingly developing resistance to antibiotics. Researchers have now found a therapeutic equivalent which could replace penicillin and related phamaceuticals.

8 Jun 2011

Novation recognizes APP with NOVAPLUS Pharmacy Manufacturer of the Year

APP Pharmaceuticals, Inc., a wholly owned subsidiary of Fresenius Kabi Pharmaceuticals Holding, Inc., has been named NOVAPLUS Pharmacy Manufacturer of the Year by Novation, the industry's leading supply contracting company.

8 Jun 2011

Rosa, Profil Institute partner to offer simulation technology for diabetes and obesity clinical trials

Profil Institute for Clinical Research, Inc., a company leading the industry in early phase clinical trials for diabetes and obesity, and Rosa & Co. LLC, a drug development advisory firm with expertise in drug-disease modeling and simulation, jointly announced today a strategic alliance to offer Profil Institute customers use of Rosa's modeling technology to simulate disease physiology, drug action, patient variability, and trial outcomes for their early phase clinical development programs.

8 Jun 2011

New palonosetron-aprepitant trial data on chemotherapy induced nausea, vomiting presented at EHA

New data presented at the European Hematology Association (EHA) 2011 Annual Meeting in London show better control of nausea and vomiting with the combination palonosetron plus aprepitant when compared to granisetron in patients receiving multiday highly emetogenic conditioning chemotherapy regimens - Significantly higher the complete response during the acute, delayed and overall periods.

8 Jun 2011

New research on spinal muscular atrophy

Spinal muscular atrophy (SMA) is the leading genetic cause of death in children under 2, with no treatment other than supportive care. In the Proceedings of the National Academy of Sciences, researchers at Children's Hospital Boston show how loss or mutation of the SMA gene causes progressive muscle degeneration and weakness, and suggest a promising approach to treating the condition, sometimes referred to as a "Lou Gehrig's disease of babies."

8 Jun 2011

Scientists find neuronal cells die in Alzheimer's disease

In what they are calling a new direction in the study of Alzheimer's disease, UC Santa Barbara scientists have made an important finding about what happens to brain cells that are destroyed in Alzheimer's disease and related dementias.

8 Jun 2011

Self-assembling mini devices now enlisted in nanomedicine revolution

Measured in billionths of a meter, self-assembling nano-sized devices designed to carry drugs and imaging agents into the body are revolutionizing medicine by improving drug solubility and bio-distribution, providing a platform for combining targeting and imaging agents, and enabling membrane barriers to be crossed as well as making drug and imaging agent combination therapies possible.

8 Jun 2011

Doctors place greater value on life-prolonging treatments rather than on quality-enhancing ones

Doctors are more apt to recommend a more costly therapy to patients if it were determined to prolong the patient's life rather than just improve quality, according to a recent study from Medical Decision Making (published by SAGE).

8 Jun 2011

Novel FRET biosensor allows measurement of intraorganellar glutathione potentials in living cells

In work published in the June 2011 issue of Experimental Biology and Medicine, Kolossov, Spring and their co-investigators - a multidisciplinary team within the Institute for Genomic Biology at the University of Illinois - have transferred the concept of redox-sensitive Green Fluorescent Proteins (GFPs) to a quantitative F-rster resonance energy transfer (FRET) imaging platform.

8 Jun 2011

Topline results from 4SC vidofludimus Phase IIb trial against rheumatoid arthritis

4SC AG, a discovery and development company of targeted small molecule drugs for autoimmune diseases and cancer, today announced topline results from its randomised, double-blind, placebo-controlled Phase IIb clinical trial COMPONENT in RA.

8 Jun 2011

Avoiding repetitive activities that increase stress on the joints may prevent bursitis

As warm weather arrives and the great outdoors beckons, more and more men and women will be taking to the trails, the beaches, or their yards and gardens, embarking on physical activities that may result in sore, aching, swollen joints.

8 Jun 2011

Scientists discover four different bacteria that can live on caffeine

As it turns out, humans aren't the only organisms that turn to caffeine for a pick-me-up. University of Iowa scientists have identified four different bacteria that actually can live on caffeine.

8 Jun 2011

MSU professor to lead acetazolamide clinical trial on idiopathic intracranial hypertension

A rare but increasingly more common disease striking overweight, younger women is the focus of a clinical trial at Michigan State University, where an osteopathic physician is testing the effectiveness of a certain drug against a potentially blindness-causing ailment.

8 Jun 2011

As health care technology advances, costs increase

The device industry has launched an aggressive campaign to avoid tighter Food and Drug Administration rules that would help generate the information needed to show whether newer devices are actually superior to the ones they replace.

8 Jun 2011

Magnetic field can reduce blood viscosity, prevent heart attacks

If a person's blood becomes too thick it can damage blood vessels and increase the risk of heart attacks. But a Temple University physicist has discovered that he can thin the human blood by subjecting it to a magnetic field.

8 Jun 2011

Drugs News and Research

New research finds 74% drop in myocardial infarction over 20-year period

Children who experience trauma more likely to have behavior and learning problems

FDA accepts Adamis IND for APC-100 to treat prostate cancer

Hepatitis C virus (HCV)-associated liver disease after liver transplantation

Childhood trauma linked to higher rates of mental health problems and obesity, says Stanford/Packard psychiatrist

Therapeutic equivalent to replace penicillin

Novation recognizes APP with NOVAPLUS Pharmacy Manufacturer of the Year

Rosa, Profil Institute partner to offer simulation technology for diabetes and obesity clinical trials

New palonosetron-aprepitant trial data on chemotherapy induced nausea, vomiting presented at EHA

New research on spinal muscular atrophy

Scientists find neuronal cells die in Alzheimer's disease

Self-assembling mini devices now enlisted in nanomedicine revolution

Doctors place greater value on life-prolonging treatments rather than on quality-enhancing ones

Novel FRET biosensor allows measurement of intraorganellar glutathione potentials in living cells

Topline results from 4SC vidofludimus Phase IIb trial against rheumatoid arthritis

Avoiding repetitive activities that increase stress on the joints may prevent bursitis

Scientists discover four different bacteria that can live on caffeine

MSU professor to lead acetazolamide clinical trial on idiopathic intracranial hypertension

As health care technology advances, costs increase

Magnetic field can reduce blood viscosity, prevent heart attacks

Drug Discovery - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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