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Trevena completes $35M Series B financing

Trevena, Inc., the leader in discovery and development of G-protein coupled receptor biased ligands, announced today that it has completed a $35 million Series B financing. Existing investors Polaris Venture Partners and New Enterprise Associates led the round, with all other existing Trevena investors - Alta Partners, Healthcare Ventures and Yasuda Enterprise Development Company - also participating in the financing.

14 Jul 2010

Research provides better understanding of drugs used to treat, prevent cardiovascular disease

Using chemical labeling and mass spectrometry-based techniques, Mark Chance, PhD, director of the Case Western Reserve University School of Medicine Center for Proteomics and Bioinformatics and professor of physiology and biophysics; Sayan Gupta, PhD, instructor at the Case Center for Proteomics and Bioinformatics; and a research team from the University of Oxford, for the first time, were able to take a high resolution picture of the open state of a K+ channel, allowing them to comparatively analyze gating mechanisms important to heart function and nerve signaling - in addition these techniques have already permitted Case Western investigators to gain a deeper understanding of G-protein coupled receptors.

14 Jul 2010

BioInvent reports net revenues of SEK 63.1M for January - June 2010 period

BioInvent reached an important milestone when the results of a phase II trial of TB-402 following orthopaedic surgery, were reported in May. The data showed that TB-402 is statistically better at preventing thrombosis than enoxaparin, the current standard treatment. Supported by these good results, BioInvent and the company's partner, ThromboGenics, will now prioritise securing a development partner for the programme to ensure that the necessary resources is in place to take the product candidate to the market.

14 Jul 2010

Media outlets focus on audiences towards Alzheimer's disease: Intellect Neurosciences

Intellect Neurosciences, Inc., a biopharmaceutical company engaged in the discovery and development of disease-modifying therapeutic agents for the treatment and prevention of Alzheimer's disease, today announced that it is pleased with the recent press coverage the Company and Dr. Daniel G. Chain, Ph.D., the Company's Chairman and Chief Executive Officer, recently has received.

14 Jul 2010

First Edition: July 14, 2010

Today's headlines reflect coverage of new federal rules related to "meaningful use" of electronic health records as well as the latest on the federal deficit, the White House's new HIV/AIDS strategy and other developments.

14 Jul 2010

Concerns about violence in Mexico have led majority of firms to scale back operations: Survey

Concerns about violence in Mexico have led a majority of firms polled to scale back their level of operations there, or to consider doing so, according to a new survey released by International SOS Assistance, Inc.

14 Jul 2010

Highlights of AAPM 52nd meeting

The 52nd meeting of the American Association of Physicists in Medicine (AAPM) convenes from July 18 - 22, 2010 in Philadelphia, PA.

14 Jul 2010

Call for clarification, education on enactment of new FSA restriction

A provision of health care reform could blindside consumers and create an administrative nightmare for providers and retailers as its January 1, 2011 implementation date draws closer. Without intervention, the Patient Protection and Affordable Health Care Act, passed earlier this year, will require consumers to obtain a physician's "prescription" in order to use their pre-tax flexible spending accounts (FSAs) to pay for over-the-counter (OTC) medicines other than insulin.

14 Jul 2010

Researchers examine long-term cause-specific mortality among childhood cancer survivors

Follow-up of a group of British childhood cancer survivors indicates they have an increased risk of death from second primary cancers and cardiac and cerebrovascular causes more than 25 years after their initial cancer diagnosis, according to a study in the July 14 issue of JAMA.

14 Jul 2010

Researcher to lead $14.5M project to fight malaria in Southeast Asia

A researcher in Penn State's College of Agricultural Sciences will lead a seven-year, $14.5 million project to fight malaria in Southeast Asia. Liwang Cui, professor of entomology, is the principal investigator for the Southeast Asia Malaria Research Center, one of 10 International Centers of Excellence for Malaria Research announced by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

14 Jul 2010

Drugs taken for common medical conditions cause long term cognitive impairment in older adults: Study

Drugs commonly taken for a variety of common medical conditions including insomnia, allergies, or incontinence negatively affect the brain causing long term cognitive impairment in older African-Americans, according to a study appearing in the July 13, 2010 print issue of Neurology, the medical journal of the American Academy of Neurology.

14 Jul 2010

In N.J., patients who receive free AIDS meds to face stricter income limits; some W. Va. state employees will no longer receive monthly insurance subsidies

The (Bergen County, N.J.) Record: "New Jersey will no longer provide free AIDS medications for 950 people who are HIV-positive, under a little-noticed provision of the state budget enacted this month.

14 Jul 2010

Medicaid stalemate, pay-for-delay ban among health care items under debate

"Several states are preparing to make deep cuts to Medicaid as a federal stalemate over funding for the poor drags on—even as states face mandates to expand the program under the new health-care law." Efforts to extend provisions of the stimulus programs that provided extra federal money to state Medicaid programs remain in limbo; the enhanced funding is set to expire at the end of the year.

14 Jul 2010

FDA opens two-day hearing to examine safety of diabetes drug Avandia

The Fiscal Times: "There will be more at stake than just one drug's future when the Food and Drug Administration opens a two-day hearing Tuesday on the safety of the diabetes drug Avandia. The 30-member panel of outside experts will also be rendering judgment on research methods that are frequently used to compare effectiveness and are slated to become a pillar of the nation's drug safety monitoring system.

14 Jul 2010

LSUHSC Professor awarded $2.1M grant to determine role of PCP

Dr. Jay Kolls, Professor and Chairman of Genetics at the LSU Health Sciences Center New Orleans School of Medicine, has been awarded a $2.1 million grant over five years by the National Heart, Lung, and Blood Institute of the National Institutes of Health to determine the role and identify which T-helper cells fight the opportunistic infection, Pneumocystis carinii pneumonia, which can be a complication of HIV/AIDS.

14 Jul 2010

Administration to unveil first national HIV/AIDS strategy today

The White House will unveil the first formal national HIV/AIDS strategy on Tuesday, a plan that aims to reduce the number of new cases by 25 percent in the next five years, officials said. Noting that the number of new infections in the United States has been static -- and that the number of people living with HIV is growing -- the new policy would direct more resources toward African Americans and gay and bisexual men. Latinos and substance abusers should also be a priority, the report says.

14 Jul 2010

Opinions: Haitian rebuilding; Nuclear state vaccine initiatives; HIV rights abuses in China; HIV vaccine

The "paltry scale of the Pentagon's reconstruction endeavor [in Haiti] -- 1.6 million people displaced and the American military is contributing a few classrooms? -- is emblematic of the international response," columnist Dana Milbank writes in a Washington Post opinion piece.

14 Jul 2010

FDA to decide on Avandia’s fate Wednesday

Avandia, a drug used as a treatment for type 2 diabetes was approved for use in 1999. However controversies have surrounded it since 2007 when a Cleveland Clinic cardiologist Steven E. Nissen published a study in the acclaimed New England Journal of Medicine that concluded that the drug significantly increased the risk for heart problems like heart attacks, heart failure and deaths.

13 Jul 2010

Fredericksburg Oncology invites participants for new metastatic melanoma clinical trial

Fredericksburg Oncology is now accepting patients for a new clinical trial supported by the National Cancer Institute (NCI) to evaluate treatment for metastatic (advanced stage) melanoma. The current trial, designed at the Mayo Clinic, combines chemotherapy with targeted molecular agents in an effort to improve control of this difficult disease, reports Dr. Frederick C. Tucker, Jr., who heads this practice.

13 Jul 2010

Protalix BioTherapeutics' taliglucerase alfa for Gaucher disease granted French ATU

Protalix BioTherapeutics, Inc. announced today that the French regulatory authority has granted an Autorisation Temporaire d'Utilisation (ATU), or Temporary Authorization for Use, for taliglucerase alfa for the treatment of Gaucher disease. An ATU is the regulatory mechanism used by the French Health Products and Safety Agency to make non-approved drugs available to patients in France when a genuine public health need exists.

13 Jul 2010

Drugs News and Research

Trevena completes $35M Series B financing

Research provides better understanding of drugs used to treat, prevent cardiovascular disease

BioInvent reports net revenues of SEK 63.1M for January - June 2010 period

Media outlets focus on audiences towards Alzheimer's disease: Intellect Neurosciences

First Edition: July 14, 2010

Concerns about violence in Mexico have led majority of firms to scale back operations: Survey

Highlights of AAPM 52nd meeting

Call for clarification, education on enactment of new FSA restriction

Researchers examine long-term cause-specific mortality among childhood cancer survivors

Researcher to lead $14.5M project to fight malaria in Southeast Asia

Drugs taken for common medical conditions cause long term cognitive impairment in older adults: Study

In N.J., patients who receive free AIDS meds to face stricter income limits; some W. Va. state employees will no longer receive monthly insurance subsidies

Medicaid stalemate, pay-for-delay ban among health care items under debate

FDA opens two-day hearing to examine safety of diabetes drug Avandia

LSUHSC Professor awarded $2.1M grant to determine role of PCP

Administration to unveil first national HIV/AIDS strategy today

Opinions: Haitian rebuilding; Nuclear state vaccine initiatives; HIV rights abuses in China; HIV vaccine

FDA to decide on Avandia’s fate Wednesday

Fredericksburg Oncology invites participants for new metastatic melanoma clinical trial

Protalix BioTherapeutics' taliglucerase alfa for Gaucher disease granted French ATU

Drug Discovery - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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