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Spectrum Pharmaceuticals signs co-development and commercialization agreement with TopoTarget A/S

Spectrum Pharmaceuticals, a commercial-stage biotechnology company with a primary focus in oncology, today announced that it has entered into a co-development and commercialization agreement with TopoTarget A/S for Belinostat, a novel histone deacetylase (HDAC) inhibitor.

2 Feb 2010

Medco Health Solutions acquires DNA Direct

Committed to being at the forefront of translating personalized medicine from the science to its daily practice in healthcare, Medco Health Solutions, Inc. today announced the acquisition of DNA Direct, Inc., a leader in providing guidance and decision support for genomic medicine to patients, providers, payors and employees.

2 Feb 2010

Novelty may help prevent relapse in drug addicts

The brain's innate interest in the new and different may help trump the power of addictive drugs, according to research published by the American Psychological Association. In controlled experiments, novelty drew cocaine-treated rats away from the place they got cocaine.

2 Feb 2010

Overview of newly evolving technologies for diagnosing and monitoring HIV infections

Rising consumer awareness that early diagnosis and treatment can delay the progression of human immunodeficiency virus (HIV) to anti-immuno deficiency syndrome (AIDS) has had a telling impact on the sales of HIV tests.

2 Feb 2010

Scientists and engineers conduct research on environmental health impacts of nanomaterials

As researchers around the world hasten to employ nanotechnology to improve production methods for applications that range from manufacturing materials to creating new pharmaceutical drugs, a separate but equally compelling challenge exists.

2 Feb 2010

Extended nicotine patch therapy benefits relapsing smokers trying to quit

New research from the University of Pennsylvania School of Medicine may help more smokers keep their New Year's resolution by helping them quit smoking. Extended use of a nicotine patch - 24 weeks versus the standard eight weeks recommended by manufacturers - boosts the number of smokers who maintain their cigarette abstinence and helps more of those who backslide into the habit while wearing the patch, according to a study which will be published in the February 2 issue of Annals of Internal Medicine.

2 Feb 2010

Also in Global Health News: Retrovirus enzyme; audit of USAID program; Africa's agriculture

A study published on Sunday in the journal Nature has shed light on the enzyme integrase, "which is found in retroviruses like HIV and is a target for some of the newest HIV medicines," Reuters reports. Scientists at the Imperial College London and Harvard University grew a crystal of integrase in the lab allowing them to see the enzyme's structure. According to the news service, the scientists "said that having the integrase structure means researchers can begin fully to understand how integrase inhibitor drugs work, how they might be improved, and how to stop HIV developing resistance to them," according to the news service (Kelland, 2/1).

2 Feb 2010

New approach may prove useful in labor anesthesia, orthopedics and more

One of the holy grails of local anesthesia is the ability to achieve a long-lasting nerve block that eliminates pain sensation while not affecting motor function. Now, researchers at Children's Hospital Boston have discovered an anesthetic approach that seems to do just that.

2 Feb 2010

Study shows antiviral drugs could offer protection against HIV, Ebola, herpes and hepatitis C

The development of antibiotics gave physicians seemingly miraculous weapons against infectious disease. Effective cures for terrible afflictions like pneumonia, syphilis and tuberculosis were suddenly at hand. Moreover, many of the drugs that made them possible were versatile enough to knock out a wide range of deadly bacterial threats.

2 Feb 2010

President's fiscal year 2011 budget: FDA requests $4.03 billion for promoting and protecting public health

The U.S. Food and Drug Administration is requesting $4.03 billion to promote and protect public health as part of the President's fiscal year 2011 budget - a 23 percent increase over the agency's current $3.28 billion budget.

2 Feb 2010

Mich., R.I. look for cuts in Medicaid costs; Mass. Governor suggests taxes, fees to cover rising costs

The Holland (Mich.) Sentinel reports on possible Medicaid cuts in Michigan: "After an 8 percent reduction in Medicaid reimbursement for 2010, state health organizations say additional cuts for 2011 could be overwhelming.

2 Feb 2010

Phase III study evaluating PEP005 Gel for treatment of AK meets primary clinical endpoint

LEO Pharma today announced that in a Phase III study, PEP005 (ingenol mebutate) Gel, the company's lead candidate for the topical treatment of actinic (solar) keratosis (AK) or pre-cancerous lesions, met its primary clinical endpoint of complete clearance of AK lesions in non-head locations.

2 Feb 2010

FDA approves neurostimulation treatment for heart failure

The FDA recently approved the first study of neurostimulation as a treatment for heart failure, a chronic disease that affects nearly six million Americans and is the leading cause of hospitalization in America.

2 Feb 2010

Starpharma Holdings, Eli Lilly sign new collaborative drug research and development agreement

Starpharma Holdings Limited today announced the signing of a new agreement with Eli Lilly and Company under which Starpharma's dendrimer drug delivery technology will be applied to enhance compounds in Lilly's human pharmaceutical portfolio.

2 Feb 2010

Serious liver disorder associated with use of HIV drug, FDA warns

The U.S. Food and Drug Administration today announced that non-cirrhotic portal hypertension, a rare, but serious, liver disorder, has been reported in some HIV patients taking Videx/Videx EC (didanosine).

2 Feb 2010

More details on Obama's global health strategy expected along with budget release, Wall Street Journal reports

"The Obama administration is expected to propose in its fiscal 2011 budget Monday new funding to combat preventable and tropical diseases, malnutrition and other conditions afflicting the world's poor, as part of a strategy to broaden its approach to global health," the Wall Street Journal reports.

2 Feb 2010

Romark Laboratories commences enrollment in Alinia clinical trial for acute uncomplicated influenza

Romark Laboratories announced that it has initiated enrollment of patients in a clinical trial of Alinia® (nitazoxanide) for treating acute uncomplicated influenza including illness caused by the currently circulating H1N1 strain.

1 Feb 2010

Denim blue jeans ribbon campaign: an initiative to raise awareness about children with rare diseases

Hope – It's In Our Genes.™ The Children's Rare Disease Network (http://www.crdnetwork.org) today announced the Global Genes Project (http://www.globalgenesproject.org), an initiative designed to raise awareness about the prevalence of rare diseases that afflict millions of children worldwide. Rare disease advocates organizing the campaign selected a blue jeans denim ribbon as the international symbol of hope for children suffering from life threatening and chronically debilitating rare diseases.

1 Feb 2010

Consumers oppose prescription mandate; prefer alternative method to fight meth

Mississippians are expressing outrage at lawmakers' rush to change over-the-counter cold and allergy medicines containing pseudoephedrine (PSE) to a prescription (Rx) drug.

31 Jan 2010

Breakthrough in HIV research leads to better treatment potential

Researchers have made a breakthrough in HIV research that had eluded scientists for over 20 years, potentially leading to better treatments for HIV, in a study published today in the journal Nature.

31 Jan 2010

Drugs News and Research

Spectrum Pharmaceuticals signs co-development and commercialization agreement with TopoTarget A/S

Medco Health Solutions acquires DNA Direct

Novelty may help prevent relapse in drug addicts

Overview of newly evolving technologies for diagnosing and monitoring HIV infections

Scientists and engineers conduct research on environmental health impacts of nanomaterials

Extended nicotine patch therapy benefits relapsing smokers trying to quit

Also in Global Health News: Retrovirus enzyme; audit of USAID program; Africa's agriculture

New approach may prove useful in labor anesthesia, orthopedics and more

Study shows antiviral drugs could offer protection against HIV, Ebola, herpes and hepatitis C

President's fiscal year 2011 budget: FDA requests $4.03 billion for promoting and protecting public health

Mich., R.I. look for cuts in Medicaid costs; Mass. Governor suggests taxes, fees to cover rising costs

Phase III study evaluating PEP005 Gel for treatment of AK meets primary clinical endpoint

FDA approves neurostimulation treatment for heart failure

Starpharma Holdings, Eli Lilly sign new collaborative drug research and development agreement

Serious liver disorder associated with use of HIV drug, FDA warns

More details on Obama's global health strategy expected along with budget release, Wall Street Journal reports

Romark Laboratories commences enrollment in Alinia clinical trial for acute uncomplicated influenza

Denim blue jeans ribbon campaign: an initiative to raise awareness about children with rare diseases

Consumers oppose prescription mandate; prefer alternative method to fight meth

Breakthrough in HIV research leads to better treatment potential

Drug Discovery - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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