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A negative mGluR5 allosteric modulator shows efficacy in treating acute migraine attacks

When migraine strikes, because of severe pain, often accompanied by nausea and sensitivity to light and sound, sufferers are effectively disabled for up to 72 hours.

30 Apr 2009

Matrix protein key to fighting viruses

Researchers from Durham University's Centre for Bioactive Chemistry are developing methods that show how proteins interact with cell membranes when a virus strikes.

30 Apr 2009

Conscientiousness is a good thing in a mate

This is the first large-scale analysis of what the authors call the "compensatory conscientiousness effect," the boost in health reported by those with conscientious spouses or romantic partners. The study appears this month in Psychological Science .

30 Apr 2009

Eating fat-rich foods trigger long-term memory formation

Having strong memories of that rich, delicious dessert you ate last night?

30 Apr 2009

Rapid malaria tests improve health outcomes in practice

A new study, carried out in primary care units in Zanzibar and published in this week's issue of PLoS Medicine, evaluates the impact of rapid malaria tests on prescribing practice and clinical outcomes.

30 Apr 2009

Are we cherry picking participants for studies of antidepressants?

Findings from clinical studies used to gain Food and Drug Administration approval of common antidepressants are not applicable to most patients with depression, according to a report led by the University of Pittsburgh Graduate School of Public Health.

30 Apr 2009

A potentially better option to blocks tumors

On the heels of dismaying reports that a promising antitumor drug could, in theory, shorten patients' long-term survival, comes a promising study by a Japanese team of researchers that suggests a potentially better option.

30 Apr 2009

Drug abuse prevention programs can curb risky sexual practices in young adulthood

School-based drug education programs for adolescents can have a long-term positive impact on sexual behavior in addition to curbing substance abuse, according to a new RAND Corporation study.

30 Apr 2009

First molecular-level numerical study of gene therapy

In a recent issue of The Journal of Chemical Physics , published by the American Institute of Physics (AIP), a group of researchers at the University of California, Berkeley and Los Alamos National Laboratory describe the first comprehensive, molecular-level numerical study of gene therapy.

29 Apr 2009

Research may bring drugs with triple the absorbing power and lower toxic risks

Drug makers might be able to triple the absorbing power of some medications and lower toxic risks of others, as a result of a study at the University of Maryland, Baltimore on how bile acids travel through the gut.

29 Apr 2009

New findings on COX-2 inhibitor side effects

In searching for a simple way to identify individuals with smoking-related lung injury, scientists at Weill Cornell Medical College have stumbled upon a potential explanation for why the class of pain-relievers known as COX-2 inhibitors increases the risk of heart problems among users.

29 Apr 2009

Researchers investigate the effects of oxytocin on human couple interactions

Relationships are difficult and most of us probably think at some point that communicating positively with our partner when discussing stressful issues, like home finances, is an impossible task.

29 Apr 2009

Dendrimers as synthetic gene vectors

29 Apr 2009

New cancer centre launched in Southampton

Southampton joins a unique chain of Cancer Research UK Centres that are being launched across the UK.

29 Apr 2009

Glutamate identified as predictor of disease progression in multiple sclerosis

UCSF researchers have identified a correlation between higher levels of glutamate, which occurs naturally in the brain as a byproduct of metabolism, and greater disease burden in multiple sclerosis patients.

29 Apr 2009

New animal model for the painful nerve condition sciatica

A newly developed animal model for the painful nerve condition known as sciatica should help researchers diagnose and treat it, according to Duke University bioengineers and surgeons.

29 Apr 2009

Drugs needed to preserve eggs for reproduction need to be given in stages

Cryoprotectants needed to preserve eggs for reproduction need to be given in stages, albeit rapid ones, say scientists who have developed a mathematical model that predicts optimal time for loading and unloading these drugs.

29 Apr 2009

DNA "barcodes" used to map mosquito species in West Africa that spread lymphatic filariasis

New biotechnologies that allow scientists to quickly and accurately distinguish species based on a simple DNA analysis are being creatively deployed for the first time in the war against a major global disease.

29 Apr 2009

Aspirin for forty somethings could cut cancer risk

Taking aspirin in your 40s could cut the risk of cancer developing later in life, according to research published in the Lancet Oncology.

29 Apr 2009

Anti-viral drug telaprevir improves response, halves duration of hepatitis C treatment

The addition of the anti-viral drug telaprevir to a standard treatment for hepatitis C can shorten the duration of therapy and increase the number of patients who can be cured of their disease, according to the results of study coordinated by investigators from the Duke Clinical Research Institute (DCRI).

29 Apr 2009