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Light-powered nanomachine kills cancer cells

Researchers from the Nano Machine Center at the California NanoSystems Institute at UCLA have developed a novel type of nanomachine that can capture and store anticancer drugs inside tiny pores and release them into cancer cells in response to light.

2 Apr 2008

Scientists discover how polyketides form their ringlike shape

Many top-selling drugs used to treat cancer and lower cholesterol are made from organic compounds called polyketides, which are found in nature but historically difficult for chemists to alter and reproduce in large quantities.

2 Apr 2008

Restrictive drug policies often cause schizophrenic patients to discontinue medication

Policies requiring authorization before physicians can prescribe newer medications to schizophrenic patients may be counter-productive.

2 Apr 2008

Prednisone tablets less variable than marketed drugs

The U.S. Pharmacopeial (USP) Convention has announced results of a study comparing the dissolution variability of USP Prednisone Lot P Reference Standard tablets to two marketed drugs.

2 Apr 2008

Stimulant treatment for ADHD does not contribute to substance abuse later in life

Treating children as early as age six or seven with stimulants for Attention Deficit Hyperactivity Disorder (ADHD) is not likely to increase risk of substance abuse as adults, according to two studies funded by the National Institutes of Health (NIH).

2 Apr 2008

Bosentan drugs offers new approach to limiting organ damage in sickle cell disease

Sickle cell disease (SCD) is so called because of the abnormal sickle shape of the red blood cells in individuals with this blood disorder.

2 Apr 2008

From algae to parasites: new 'missing link' species found in Sydney Harbour

It's not often that brown algae is considered exciting or revolutionary, but Associate Professor Dee Carter from the School of Molecular and Microbial Biosciences at the University of Sydney and her former PhD student, Robert Moore, have found a new species of single-celled brown algae that is an evolutionary missing link.

2 Apr 2008

Illicit drug use increasingly glamorized in rap music

Rap music has gone from an art form that largely warned against the dangers of substance abuse to one that often glorifies illegal drug use, according to the first systematic social science study of the genre covering nearly two decades.

2 Apr 2008

Distinguishing non-TB pulmonary disease from TB

A diagnostic kit shows new promise for distinguishing between tuberculosis (TB) and its infections from disease caused by related mycobacteria family, which mimic TB and other lung disease in symptoms but require distinctly different clinical treatments.

2 Apr 2008

New breakthrough discovery on TB

Medical scientists from the University of Leicester, together with colleagues from St Georges, University of London, funded principally by the Medical Research Council (MRC) and The Wellcome Trust, have published details of a new breakthrough discovery on TB.

1 Apr 2008

A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics

Results of a randomised trial published in PLoS Medicine show no benefit in cognitive or neuropsychiatric outcomes from continuing neuroleptic drugs in patients with Alzheimer's disease.

1 Apr 2008

New research shows benefits of ultrasound contrast agents outweigh potential risk to heart patients

A Saint Louis University cardiologist called upon the U.S. Food and Drug Administration (FDA) today to reconsider a strong warning it recently placed on a diagnostic tool, stating that the warning could prevent doctors from detecting life-threatening cardiac events.

1 Apr 2008

New genetic clues to diabetes

An international team that included scientists from the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today reported it has identified six more genetic variants involved in type 2 diabetes, boosting to 16 the total number of genetic risk factors associated with increased risk of the disease.

1 Apr 2008

Disappointing resuts for pimecrolimus, investigational anti-restenosis drug

A new medication that researchers had hoped would reduce the risk of arterial renarrowing after stenting has turned in a disappointing performance in a multicenter clinical trial, but the multi-reservoir stent that was used to deliver the drug is still considered promising.

1 Apr 2008

Researchers discover how HIV can hide in cells

Researchers have discovered how Human Immunodeficiency Virus (HIV), which causes AIDS, can hide itself in our cells and dodge the attention of our normal defences, scientists heard at the Society for General Microbiology's 162nd meeting being held this week at the Edinburgh International Conference Centre.

1 Apr 2008

Diabetics have same risk for heart attack, stroke or death from cardiovascular diseases

People with diabetes have the same high risk for heart attack or stroke or cardiovascular death as people who've already had a heart attack, researchers reported in Circulation: Journal of the American Heart Association.

1 Apr 2008

New blood pressure drug Micardis (Telmisartan) good at reducing deaths from heart attacks

An international team of researchers have found that a new blood pressure medication is as effective in reducing cardiovascular death, with fewer side effects than the current treatments offered.

1 Apr 2008

Replacing absent microRNAs could make tumors less invasive, more treatable

One group of small, non-coding RNA molecules could serve as a marker to improve cancer staging and may also be able to convert some advanced tumors to more treatable stages, report a University of Chicago-based research team in the April 1, 2008, issue of the journal Genes & Development.

1 Apr 2008

Hypertension treatment for the elderly cuts the risk of heart disease and stroke

New research from Britain suggests that when the elderly are treated for hypertension (high blood pressure) the medication reduces their risk of heart disease, stroke and even death.

1 Apr 2008

Fasting could offer protection from chemotherapy effects

A new study is suggesting that short-term fasting could help protect cancer patients against the effects of chemotherapy.

1 Apr 2008

Drugs News and Research

Light-powered nanomachine kills cancer cells

Scientists discover how polyketides form their ringlike shape

Restrictive drug policies often cause schizophrenic patients to discontinue medication

Prednisone tablets less variable than marketed drugs

Stimulant treatment for ADHD does not contribute to substance abuse later in life

Bosentan drugs offers new approach to limiting organ damage in sickle cell disease

From algae to parasites: new 'missing link' species found in Sydney Harbour

Illicit drug use increasingly glamorized in rap music

Distinguishing non-TB pulmonary disease from TB

New breakthrough discovery on TB

A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics

New research shows benefits of ultrasound contrast agents outweigh potential risk to heart patients

New genetic clues to diabetes

Disappointing resuts for pimecrolimus, investigational anti-restenosis drug

Researchers discover how HIV can hide in cells

Diabetics have same risk for heart attack, stroke or death from cardiovascular diseases

New blood pressure drug Micardis (Telmisartan) good at reducing deaths from heart attacks

Replacing absent microRNAs could make tumors less invasive, more treatable

Hypertension treatment for the elderly cuts the risk of heart disease and stroke

Fasting could offer protection from chemotherapy effects

Drug Discovery - Second Edition eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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