Drugs News and Research

RSS

Brain circuitry that drives drug-seeking compulsion identified

In experiments with rats, researchers have identified the change in brain circuitry that drives development of a compulsion to seek drugs, even when that compulsion is self-destructive.

7 Feb 2008

U.S. FDA approval of generic Fosamax

The U.S. Food and Drug Administration today approved the first generic versions of Fosamax (alendronate sodium tablets), used to treat osteoporosis, a condition that causes thinning and weakening of a person's bones.

6 Feb 2008

Getting under the skin of HIV, hep C

The University of New South Wales (UNSW) is working towards a new approach to treat people with HIV/AIDS, with a drug which has already shown promise in the laboratory.

5 Feb 2008

People with manic depression have a distinct chemical signature in their brains

People with manic depression have a distinct chemical signature in their brains, according to a new study. The research, published in the journal Molecular Psychiatry, may also indicate how the mood stabilisers used to treat the disorder counteract the changes in the brain that it appears to cause.

5 Feb 2008

New cancer center at NewYork-Presbyterian/Weill Cornell

NewYork-Presbyterian Hospital/Weill Cornell Medical Center has created an expanded cancer program dedicated to advancing research, prevention and treatment of the disease. The new Cancer Center is led by renowned cancer physician-scientist Dr. Andrew Dannenberg.

5 Feb 2008

Taking more than one NSAID may lead to complications

Nonsteroidal anti-inflammatory drugs (NSAIDs) are used to treat arthritis, which affects one-third of all adults.

5 Feb 2008

Study of successful drug targets could hasten development of new medications

Guidance from an innovative computational approach could speed up the process and cut down the cost of new drug development, researchers from the University of Chicago Medical Center and Columbia University suggest in a study to be published in the February 2008 issue of Genome Research, available early online.

5 Feb 2008

Enbrel shown to significantly reduced levels of C-reactive protein

Amgen and Wyeth Pharmaceuticals, a division of Wyeth have announced findings from a retrospective analysis, which demonstrated that ENBREL reduced C-reactive protein (CRP), a marker of inflammation, in patients with moderate to severe plaque psoriasis following 12 weeks of treatment. Median reduction in CRP levels was 10 times greater in the ENBREL treated group compared to the placebo treated group.

5 Feb 2008

Chemists track how amantadine drug changes, blocks flu virus

An anti-virus drug attacks influenza A by changing the motion and structure of a proton channel necessary for the virus to infect healthy cells, according to a recently published research paper by two Iowa State University chemists.

5 Feb 2008

Antiepileptic drug warning from FDA

The U.S. Food and Drug Administration today issued new information to health care professionals to alert them about an increased risk of suicidal thoughts and behaviors (suicidality) in patients who take drugs called antiepileptics to treat epilepsy, bipolar disorder, migraine headaches, and other conditions.

5 Feb 2008

Eye blinks may help to identify children prenatally exposed to alcohol

While children with fetal alcohol syndrome (FAS) have identifiable craniofacial abnormalities, children with alcohol-related neurodevelopmental disorder (ARND) can have significant cognitive impairments without facial anomalies. An important new study has found that a deficit in eyeblink conditioning (EBC) can identify children with probable FAS, and may also serve to identify alcohol-exposed children who lack distinctive FAS features.

5 Feb 2008

Novel drug romiplostim significantly improves treatment of dangerous blood disorder

Two clinical trials of the novel drug romiplostim (Nplate) show that it significantly improved platelet levels in patients with chronic immune thrombocytopenic purpura (ITP), a hematologic disorder that can cause uncontrolled bleeding.

5 Feb 2008

Ascal (calcium carbasalate) not safer than aspirin

Changing prescription of low-dose aspirin into calcium carbasalate (brand name: Ascal) to prevent peptic ulcerations is not useful. Peptic ulcers are evenly distributed among users of calcium carbasalate and aspirin, for secondary prevention of myocardial infarction.

5 Feb 2008

Insomnia patients often denied sleep treatment when they have mental health problems

Patients with insomnia who are diagnosed with accompanying mental health ailments often are not prescribed medication that will help them sleep - which could then make related anxiety or depression worse, new research suggests.

4 Feb 2008

Breaking down Huntington's disease one protein at a time

Hoping to piece together the intricate series of interactions that lead to Huntington's disease, Indiana University Bloomington scientists have determined the shape and structure of a binding site that may prove useful in combating the neurodegenerative disease

4 Feb 2008

NACDS launches campaign to expand role in healthcare debate

Pharmacy is vital to healthcare quality, affordability and accessibility, and should be valued and utilized more completely. That is the message of a major advertising campaign launched today by the National Association of Chain Drug Stores (NACDS) as part of its increasingly proactive outreach to policymakers to tell the story of its members.

4 Feb 2008

Researchers uncover key interaction in cholesterol regulation

Researchers at UT Southwestern Medical Center have determined the specific way in which a destructive protein binds to and interferes with a molecule that removes low-density lipoproteins (LDL), the so-called "bad" cholesterol, from the blood.

4 Feb 2008

Bush's efforts to rein in government spending places a dangerous target on health care

President George W. Bush today submitted his budget proposal to Congress for fiscal year 2009. In response Bruce Roberts, RPh, executive vice president and CEO of the National Community Pharmacists Association (NCPA) issued the following statement:

4 Feb 2008

Breastfeeding now safer for infants of HIV-infected mothers

An antiretroviral drug already in widespread use in the developing world to prevent the transmission of HIV from infected mothers to their newborns during childbirth has also been found to substantially cut the risk of subsequent HIV transmission during breast-feeding.

4 Feb 2008

Less waste in the synthesis of anti-inflammatory drugs

Dr Francesca Paradisi of the Centre for Synthesis and Chemical Biology (CSCB) at University College Dublin, and Professor Daria Giacomini and co-workers at the University of Bologna, Italy, have developed a highly efficient enzyme-driven process which could be applied to the synthesis of drugs such as Ibuprofen, avoiding the 50% waste of the undesired byproduct generated by current processes.

4 Feb 2008