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New Parkinson's disease research points to serotonin

For most people with Parkinson's disease, the only relief from the tremors, rigidity and impaired movement associated with the progressive loss of their motor skills is a drug called L-DOPA. But as the disease progresses, L-DOPA can cause prominent side effects that counteract its effectiveness.

4 Feb 2008

USA Today examines possible reasons for five-year low of FDA drug approval rate

USA Today on Monday examined how some pharmaceutical industry analysts cite "more cautious regulators and less innovation by drug makers" as reasons for the low rate of new drug approvals in 2007 (Schmit, USA Today, 2/4).

4 Feb 2008

Researchers examine immune cells where HIV can lie dormant, possible treatments

Researchers have determined how HIV is able to lie dormant in certain immune system cells and prevent the cells from self-destructing, according to a study published Thursday online in the journal Retrovirology, the AP/Google.com reports.

4 Feb 2008

Scientists identify protein's crucial role in resistance to breast cancer treatment

Scientists at the Breakthrough Breast Cancer Research Centre at The Institute of Cancer Research in London have identified how some breast cancers may become resistant to hormone treatments like tamoxifen.

4 Feb 2008

Nausea from chemotherapy explained

A new study from the Monell Center increases understanding of the biological mechanisms responsible for the nausea and vomiting that often afflict patients undergoing chemotherapy.

4 Feb 2008

Neurogenesis plays an important role in the acquisition and storage of spatial memory

Boosted by physical and mental exercise, neural stem cells continue to sprout new neurons throughout life, but the exact function of these newcomers has been the topic of much debate.

4 Feb 2008

New anti-HIV medication etravirine shows great promise

The AIDS Institute, a national public policy research, advocacy, and education organization, is encouraged with the FDA's approval of the first new non-nucleoside reverse transcriptase inhibitor (NNRTI) in nearly a decade.

4 Feb 2008

Enzyme released by mast cells in the lungs could be a new target for asthma

An enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma pointing to a potential new target for treatment against the illness.

4 Feb 2008

Subconscious signals can trigger drug craving

Using a brain imaging technology called functional magnetic resonance imaging (fMRI), scientists have discovered that cocaine-related images trigger the emotional centers of the brains of patients addicted to drugs even when the subjects are unaware they've seen anything.

4 Feb 2008

Porous structures help boost integration of host tissue with implants

Results published in FASEB (the journal of the Federation of American Societies for Experimental Biology) by researchers at Columbia University, including Jeremy Mao of the Columbia College of Dental Medicine, demonstrate a novel way of using porous structures as a drug-delivery vehicle that can help boost the integration of host tissue with surgically implanted titanium.

4 Feb 2008

New target for flu prevention

Emerging subtypes of influenza A virus hold the potential to initiate a world-wide epidemic in the next few years, according to World Health Organization officials.

4 Feb 2008

Effects of prostate removal

Men with prostate cancer who have their prostate removed cite sexual dysfunction as the most common side effect after surgery, but urinary dysfunction troubles these patients most, reports a University of Florida researcher. What's more, many aren't emotionally prepared to face these complications.

4 Feb 2008

New Zealand warns of risk from anti-epileptic drugs

New Zealand's Ministry of Health drug regulation arm Medsafe is alerting health care professionals about a small increased risk of suicidal thoughts and behaviours in patients taking anti-epileptic medicines.

31 Jan 2008

Why is scratching so nice?

In the first study to use imaging technology to see what goes on in the brain when we scratch, researchers at Wake Forest University Baptist Medical Center have uncovered new clues about why scratching may be so relieving - and why it can be hard to stop. The work is reported online in the Journal of Investigative Dermatology and will appear in a future print issue.

31 Jan 2008

Virtual human in HIV drug simulation

The combined supercomputing power of the UK and US 'national grids' has enabled UCL (University College London) scientists to simulate the efficacy of an HIV drug in blocking a key protein used by the lethal virus.

31 Jan 2008

Lungs' mast cells could provide new treatment target for asthma, other respiratory disease

30 Jan 2008

Number of HIV cases among seniors in Puerto Rico increasing

The number of new HIV cases recorded among people ages 60 and older in Puerto Rico is increasing, the Miami Herald reports.

30 Jan 2008

Bush in State of the Union address calls on Congress to allocate $30 billion for PEPFAR

President Bush on Monday during his last State of the Union address urged Congress to authorize a $30 billion, five-year extension of the President's Emergency Plan for AIDS Relief, the New York Times reports (Stolberg, New York Times, 1/29).

30 Jan 2008

Brazil to distribute 19.5 million condoms during carnival

Health officials in Brazil on Sunday began distributing millions of condoms ahead of the country's five-day Carnival in an effort to reduce the spread of HIV and other sexually transmitted infections, the AP/San Diego Union-Tribune reports.

30 Jan 2008

Antidepressants might be worthless for treating low back pain

The review appears in the latest issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

30 Jan 2008