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Homelessness increases risk of infection for injecting drug users

A new report from the Health Protection Agency shows that around three-quarters of injecting drug users (IDUs) have been homeless at some point. In addition, those who have been homeless have higher levels of injecting risk and associated infections, primarily through the sharing of needles and low standards of hygiene.

29 Oct 2007

Hairpin-shaped mimetics imitate the helical protein that plays a role in the spread of HIV

When a host cell is infected with HIV, the virus brings its own genetic material into the host cell. This cell then replicates, reads the viral RNA, and uses it as a blueprint to produce more viral proteins.

29 Oct 2007

Deep brain stimulation to treat Parkinson's makes some act irrationally

An implantable brain device meant to help Parkinson's disease patients better control their movements, has been found to have some worrying side-effects.

29 Oct 2007

Researchers find new mechanism explaining the promotional effect of H pylori on gastric cancer

The formation of a cancer is proven to be a multi-stage, multi-mechanism process by animal and human studies.

28 Oct 2007

FDA issues communication on ongoing safety review of Aprotinin injection

Last week, FDA was notified that a Canadian research group stopped a study on Trasylol because the drug appeared to increase the risk for death compared to the other antifibrinolytic drugs used in the study. Antifibrinolytic drugs help slow the breakdown of blood clots and subsequent excessive bleeding.

28 Oct 2007

New model of HIV dynamics

The emergence of drug resistant forms of HIV often underlies the failure of current antiretroviral therapies for HIV infection.

28 Oct 2007

Discovery of a key cell-signaling pathway

University of Alabama at Birmingham (UAB) researchers have discovered a key cell-signaling pathway that regulates cell progression and switches on front-to-back body patterning in tadpoles.

28 Oct 2007

Hypertension drugs may prevent Alzheimer's Disease

New research is suggesting that some of the drugs commonly used to treat hypertension (high blood pressure) may offer another benefit.

28 Oct 2007

New and safer infertility treatment produces healthy twins

The treatment known as in-vitro maturation or IVM, enables infertile couples to conceive without the need for the woman to take powerful hormonal drugs to stimulate her ovaries.

28 Oct 2007

Teenage smokers at risk of depression, alcohol abuse and drug use

According to American researchers smoking cigarettes may make teens more prone to depression, alcohol abuse and illegal drug use.

28 Oct 2007

Emerging cancer therapies and novel targets

What are the cancer drugs of tomorrow and how will they be developed? At the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, researchers will present some answers to these and other pressing questions regarding emerging cancer therapeutics.

25 Oct 2007

Blood markers can help choose best dose for antiangiogenic drugs

Scientists at Sunnybrook have new information that may help to improve the use of anti-cancer drugs designed to block the growth of new blood vessels in tumors, a process called angiogenesis that is critical to tumor growth.

25 Oct 2007

Stanford researchers get precise picture of cell target for drugs

More than half of all drugs given to patients work by targeting a particular type of "docking station," or receptor, found on body cells, to steer the cell's machinery toward healing an illness.

25 Oct 2007

Public not so sure about 'personalized medicine'

Ordinary people worry about the extra, and often burdensome, responsibilities which could come with scientists' promises of 'personalised medicine', according to evidence to be presented at a major two-day showcase of groundbreaking social science research into the whole field of genomics, funded by the Economic and Social Research Council (ESRC).

25 Oct 2007

Promising new tuberculosis drug given special status

Approximately one-third of the world's population is infected with Mycobacterium tuberculosis, the bacterium that causes TB, and an estimated 1.6 million people died of the disease in 2005.

25 Oct 2007

Valsartan might help prevent Alzheimer's disease

Alzheimer disease (AD), a neurodegenerative disease that is the most common form of dementia, is characterized by the formation in the brain of plaques containing misfolded beta-amyloid protein.

25 Oct 2007

Cow infections could provide clue to preventing infertility in women

Researchers at the Royal Veterinary College, London, have made a significant breakthrough in their understanding of how infection of the uterus damages fertility in cows.

25 Oct 2007

Human decision-making linked to an individuals' need to maintain a homeostatic balance

A researcher at the University of California, San Diego (UCSD) School of Medicine suggests that psychiatrists may need to approach the treatment of psychiatric patients from a new direction - by understanding that such individuals' behavior and decision-making are based on an attempt to reach an inner equilibrium.

25 Oct 2007

New target for Hepatocellular carcinoma therapy

Hepatocellular carcinoma (HCC) is a major health problem worldwide. Currently, the only chance for obtaining a cure in patients with HCC is by either a surgical resection or liver transplantation.

25 Oct 2007