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Oglufanide disodium in new hepatitis C trial

Physicians at Southern Health have started a phase IIa clinical trial designed to test the efficacy of a new strategy for defeating hepatitis C viral infection, one of the toughest infectious diseases in the modern world.

26 Aug 2007

Sildenafil increases release of key reproductive hormone oxytocin

Researchers at the University of Wisconsin-Madison report this month that sildenafil increases the amount of oxytocin released by stimulation of the posterior pituitary gland, a small structure directly underneath the brain that regulates hormone levels in response to neural signals.

24 Aug 2007

Blocking angiogenesis signaling from inside cell may lead to serious health problems

Angiogenesis inhibitors that block a tumor's development of an independent blood supply have been touted as effective cancer fighters that result in fewer side effects than traditional chemotherapy.

24 Aug 2007

Networking in living cells may hold key to fighting diseases

Scientists in Manchester are working to change the social habits of living cells an innovation that could bring about cleaner and greener fuel and help fight diseases such as cancer and diabetes.

From The University of Manchester 24 Aug 2007

Nanoparticle drug delivery system for brain tumor therapy shows promise

A nanoparticle drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by University of Nottingham scientists.

24 Aug 2007

UVA protection in sunscreens to be shown

The U.S. Food and Drug Administration today proposed a new regulation that sets standards for formulating, testing and labeling over-the-counter (OTC) sunscreen drug products with ultraviolet A (UVA) and ultraviolet B (UVB) protection.

24 Aug 2007

New options in treating pigmentation disorders

Melanocytes are not the only cells responsible for differences in skin coloration. New research from the University of Cincinnati (UC) has shown that some of the most basic cells on the skin's surface influence pigment production and help regulate skin coloration.

24 Aug 2007

Breakthrough for Huntington's disease

A major breakthrough in the understanding and potential treatment of Huntington's disease has been made by scientists at the University of Leeds.

24 Aug 2007

People ages 57 to 85 think of sexuality as an important part of life

The first comprehensive national survey of sexual attitudes, behaviors and problems among older adults in the United States has found that most people ages 57 to 85 think of sexuality as an important part of life and that the frequency of sexual activity, for those who are active, declines only slightly from the 50s to the early 70s.

24 Aug 2007

New ways to control fever-induced seizures

When your body cranks up the heat, it's a sign that something's wrong and a fever is designed to help fight off the infection.

24 Aug 2007

Scientists investigate initial molecular mechanism that triggers neuronal firing

Carnegie Mellon University chemists have solved a decade-long molecular mystery that could eventually help scientists develop drug therapies to treat a variety of disorders, including epilepsy and Alzheimer's disease.

24 Aug 2007

All eukaryotic kinases share 1 common set of substrates

Kinase mediated phosphorylation is generally recognised as the major regulator of virtually all metabolic activities in eukaryotic cells including proliferation, gene expression, motility, vesicular transport and programmed cell death.

24 Aug 2007

Rapamycin study is first stage in development of new treatment

Rapamycin isn't your ordinary potential anti-cancer drug…It had a long and somewhat exotic history before undergoing preclinical (laboratory-based) studies at St. Jude as part of a national Pediatric Preclinical Testing Program (PPTP) investigation of its anticancer activity.

23 Aug 2007

Cancer stem cell scientists get $1.7 million to develop new leukemia drugs

"Modern cancer treatments fail to get to the root of the cancer - the stem cells - which is why many cancers recur despite aggressive treatment."

23 Aug 2007

More informative labels proposed for sunscreens

The Food and Drug Administration (FDA) in the United States has proposed new regulation governing the development and testing of sunscreens; they also want warnings on the labels about the risk of skin cancer linked to sun exposure.

23 Aug 2007

Antipsychotic drug Risperdal approved for use in children

The Food and Drug Administration (FDA) in the U.S. has given approval for the antipsychotic drug Risperdal to be used to treat schizophrenia and bipolar disorder in children and teenagers.

23 Aug 2007

South African experts say food no substitute for medical drugs in AIDS and TB

A report by the Academy of Science of South Africa has stated that there is no evidence to support the theory that a healthy diet is a substitute for medical drugs when it comes to treating HIV/AIDS and tuberculosis (TB).

22 Aug 2007

Antitumour drugs impede DNA uncoiling by topoisomerase I

The annoying bulges of an overwound telephone cord that shorten its reach and limit a caller's motion help explain why drugs called camptothecins are so effective in killing cancer cells, according to investigators led by Mary-Ann Bjornsti, Ph.D., at St. Jude Children’s Research Hospital, and Nynke Dekker, Ph.D., at Delft Technology University.

22 Aug 2007

Multifunctional nanoparticles for combining ultrasonic tumor imaging and targeted chemotherapy

A new targeted drug delivery method, which combines two nanoparticles into one larger one, uses ultrasound to image tumors and release the anticancer drug doxorubicin from "nanobubbles" into the same tumors.

22 Aug 2007