Drugs News and Research

RSS

Use of antithrombotics means more intracerebral haemorrhagic stroke deaths in over 75s

A study suggests that the number of pensioners over 75 dying from intracerebral haemorrhagic stroke has increased in the last 25 years due to use of antithrombotic drugs.

2 May 2007

Recommended doses of ginseng, ginko biloba do not interfere with drug absorption

Recent findings that the widely-used herbal supplement Saint John's wort could dramatically affect the absorption and metabolism of many prescription and non-prescription drugs raised concerns that other popular herbal supplements might cause similar changes, thus significantly altering drugs, therapeutic or toxic effects.

2 May 2007

Consumers have broad access to pharmacy choices

Consumers have broad access to pharmacy choices in urban, suburban, and rural areas, as an average of 21 pharmacies are located and compete near independent pharmacies throughout the United States, according to an analysis conducted by SK&A Information Services and released by the Pharmaceutical Care Management Association (PCMA).

2 May 2007

OCT1 required for therapeutic effects of diabetes drug Metformin

The drug metformin is among the most widely prescribed drugs for the treatment of type 2 diabetes and results in an array of therapeutic benefits.

2 May 2007

New treatments have major impact on heart failure rates

Deaths from severe heart attacks following admission to hospital have nearly halved in six years as a result of advances in medical treatment.

2 May 2007

Phenoxodiol, an investigational drug shows promise for ovarian cancer

A new study further supports the unique mechanism of action of phenoxodiol, an investigational drug being studied for the treatment of ovarian cancer.

2 May 2007

Statin drugs also may help reduce risk of heart failure

Statin drugs, known primarily for their ability to lower cholesterol, also may reduce the overactive sympathetic nervous system response that contributes to the worsening of heart failure and increases the risk of sudden cardiac death, two University of Missouri-Columbia researchers have found. Heart failure is the leading cause of morbidity and mortality in the United States.

2 May 2007

1758 cases of malaria reported in UK travellers in 2006

1386 of the cases were due to the potentially fatal Plasmodium falciparum which is a major international health risk and which kills more than a million people a year in Africa. 219 were due to Plasmodium vivax which causes a debilitating disease, but is rarely fatal.

2 May 2007

Magnesium loss In patients given monoclonal antibodies

97% of patients with cancer treated with monoclonal antibodies—cetuximab, matuzumab, or panitumumab—that target the epidermal growth factor receptor (EGFR) have some degree of magnesium loss (hypomagnesaemia), according to a study published in the May issue of The Lancet Oncology.

2 May 2007

Variants of two genes involved in the inflammatory system linked to cognitive decline after heart surgery

Duke University Medical Center researchers believe their findings could help physicians identify patients at risk of suffering mental decline after heart surgery and raises the possibility that these patients could be treated with drugs that are known to dampen the inflammatory response.

2 May 2007

Efforts to standardize heart care are working

People who suffer a heart attack or severe chest pain today are much less likely to die, or to experience long-lasting effects, than their counterparts even a few years ago, according to a new international study in the May 3 issue of the Journal of the American Medical Association.

2 May 2007

Generic biologic drugs unlikely to be cheaper than brand-name drugs

Generic versions of a class of medicines called "biologics" would not be significantly cheaper than brand-name versions of the medicines, according to research from professors at Duke University's Fuqua School of Business.

2 May 2007

FDA announces new food protection post

Commissioner of Food and Drugs Dr. Andrew C. von Eschenbach today announced the creation of the position of Assistant Commissioner for Food Protection to provide advice and counsel to the Commissioner on strategic and substantive food safety and food defense matters.

2 May 2007

Spherix starts phase 3 clinical trial of treatment for type 2 diabetes

Spherix Incorporated has announced that it has begun its Phase 3 clinical trial of Naturlose as a treatment for Type 2 diabetes.

2 May 2007

Rituximab reduces disease activity in multiple sclerosis

A new drug under investigation shows a reduction in disease activity in multiple sclerosis (MS), according to two studies that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston. The drug reduced disease activity as indicated by MRI scans.

2 May 2007

Ultra fast and ultra active: the strange life of the extraocular muscles

The eye, often called the window to the soul, may become a window to the mysteries of muscular dystrophy, a debilitating muscle disease that often leads to death in early adulthood.

2 May 2007

Wrapping version of Gleevec fights drug-resistant cancer

A new study highlighted on the cover of this week's issue of Cancer Research finds that the anti-cancer drug Gleevec? is far more effective against a drug-resistant strain of cancer when the drug wraps the target with a molecular bandage that seals out water from a critical area.

2 May 2007

New compounds show potential for cognitive disorders

UC Irvine researchers have identified a new class of compounds that could be used for drugs to treat cognitive disorders that accompany schizophrenia, Alzheimer's disease and ADHD, according to an article published today in the online version of the Proceedings of the National Academy of Sciences.

2 May 2007

Levosimendan compared to dobutamine for decompensated heart failure

The drug levosimendan did not improve survival for patients with decompensated heart failure when compared with a more widely-used treatment for this condition, dobutamine, according to a study in the May 2 issue of JAMA.

2 May 2007

Unstable leukemia stem cells may predispose patients to drug resistance

The BCR-ABL gene in chronic myeloid leukemia stem cells has a tendency to quickly mutate, and this may help explain why patients are predisposed to resistance to drugs like imatinib that target that gene, according to a study in the May 2 Journal of the National Cancer Institute.

2 May 2007