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Cardiac regeneration using stem cells may heal hearts even years after heart attacks

Left ventricular function and exercise capacity increased, while the area of heart muscle damage shrank, in 18 patients given infusions of their own bone marrow stem cells up to eight years after a heart attack, according to a new study in the Nov. 1, 2005, issue of the Journal of the American College of Cardiology.

27 Oct 2005

Natural blood sugar level lowering compound could lead to new drugs to treat type 2 diabetes

A carbohydrate isolated from the liver lowers blood sugar levels after it is injected into diabetic rats, according to research carried out by a team of experts at the University of Virginia Health System (UVHS).

27 Oct 2005

FDA panel says approval for new depression drugs needs to be faster

According to a Food and Drug Administration (FDA) advisory panel, drug makers seeking U.S. approval of new drugs to treat major depression should not be required to first provide data on how well they work long-term.

26 Oct 2005

Way now clear for use of costly breast cancer drug throughout UK

Health managers in the UK have virtually been ordered to pay for the drug Herceptin for women with an aggressive form of breast cancer in its early stages.

26 Oct 2005

Australian researchers determine structure of JAK2 kinase, huge implications for development of new cancer drugs

Researchers from Monash's Department of Biochemistry and Molecular Biology have determined the structure of the protein JAK2 kinase, a discovery with huge implications for the design and development of new cancer drugs.

25 Oct 2005

Little evidence exists to support the widespread use of bronchodilators to treat children and adults with cystic fibrosis

"Recurrent wheeze and breathlessness are common in people with cystic fibrosis, and bronchodilators are commonly prescribed," according to lead author Clare Halfhide, M.D., of the Royal Liverpool Children's Hospital in England. "Despite their wide-scale and often long-term use, there is limited objective evidence about their efficacy in cystic fibrosis."

25 Oct 2005

Lawyers' salaries in private sector impact whether drug cases go to trial

Assistant U.S. attorneys in districts with high private salaries are more likely to take a drug-trafficking case to trial than are assistant attorneys in districts with low private salaries, according to a study by economists at Rice University and Colgate University that is published in the October issue of the Journal of Law and Economics.

25 Oct 2005

New strategies to help developing countries address neglected diseases

For the health challenges facing developing countries, the numbers alone are staggering. Every day, 40,000 people - enough to fill a sports stadium - die from preventable infectious diseases and malnutrition. Entire generations of human potential are perishing.

25 Oct 2005

Growth hormone illegal for off-label anti-aging use

Because of 1988 and 1990 amendments to the Food, Drug and Cosmetic Act, off-label distribution or provision of human growth hormone to treat aging or age-associated illnesses is illegal in the United States, according to a report in the Journal of the American Medical Association.

25 Oct 2005

Gene therapy used to successfully treat heart failure

University of Pittsburgh investigators have for the first time used gene therapy to successfully treat heart failure and other degenerative muscle problems in an animal model that is genetically susceptible to a human muscular dystrophy.

25 Oct 2005

Antisense molecules may hold promise in treating brain chemical problems such as Alzheimer's

Saint Louis University research shows a new class of drugs may hold promise in treating brain chemical problems such as Alzheimer's disease, says the principal investigator of research published in an early on-line version of Peptides.

25 Oct 2005

Single blast of ultrasound destroys cancer cells

Scientists at the University of Dundee have demonstrated that cancer cells can be targeted and destroyed by a single blast of ultrasound according to an article published in leading scientific journal "Nature-Physics".

25 Oct 2005

Wellcome Trust awards £8.1 million to tackle tropical diseases

The Wellcome Trust, one of the world’s largest medical charities, has awarded £8.1 million over 5 years to a team of six scientists at the University of Dundee to help discover new drugs to treat some of the world’s most neglected tropical diseases.

25 Oct 2005

Counterfeit Tamiflu drug a very real threat

Health officials in the U.S. have expressed concern that with the current panic in many countries regarding bird flu, a counterfeit industry to produce the drug Tamiflu may already be in existence.

25 Oct 2005

Viagra significantly reduces stress on the heart

According to the results of a new study by researchers at Johns Hopkins, Viagra, a drug used to treat erectile dysfunction (ED) in millions of men, reduces the stimulatory effects of hormonal stress on the heart by half.

25 Oct 2005

Cholesterol levels and use of statins are not associated with breast cancer risk

Although some evidence suggests that statins (the most commonly used type of lipid-lowering drugs) may inhibit tumor development and may work in combination with chemotherapy drugs against cancer, studies on the association between the use of statins and breast cancer have had conflicting results

25 Oct 2005

Viagra may be the next drug treatment for heart problems

Sildenafil citrate (Viagra), a drug used to treat erectile dysfunction (ED) in millions of men, reduces the stimulatory effects of hormonal stress on the heart by half, according to results of a new study by researchers at Johns Hopkins.

24 Oct 2005

NK-1 receptor antagonists very effective at reducing vomiting after surgery

The results of a new Phase III clinical trial have demonstrated that a new class of drugs, called "NK-1 receptor antagonists," is more effective at reducing vomiting after surgery than the most commonly used drug, according to the Duke University Medical Center researchers who led the trial.

24 Oct 2005

Leeches, useful tools in the treatment of cardiovascular diseases

The leech has recently confirmed its biomedical interest for scientists by showing that it contains an extensive list of new potential molecules that may become useful tools in the treatment of cardiovascular diseases.

24 Oct 2005

Botulinum toxin successfully treats trigeminal neuralgia

There is another use for botulinum toxin which has brought relief to some who suffer from migraines and eye spasms. Botulinum toxin can also successfully treat intense facial pain called trigeminal neuralgia, according to a study published in the October 25, 2005, issue of Neurology

24 Oct 2005