E. coli News and Research

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E. coli or Escherichia coli is the name of a type of bacteria that lives in your intestines. Most types of E. coli are harmless. However, some types can make you sick and cause diarrhea. One type causes travelers' diarrhea. The worst type of E. coli causes bloody diarrhea, and can sometimes cause kidney failure and even death. These problems are most likely to occur in children and in adults with weak immune systems. You can get E. coli infections by eating foods containing the bacteria. To help avoid food poisoning and prevent infection, handle food safely. Cook meat well, wash fruits and vegetables before eating or cooking them, and avoid unpasteurized milk and juices. You can also get the infection by swallowing water in a swimming pool contaminated with human waste. Most cases of E. coli infection get better without treatment in 5 to 10 days.

Alexion begins eculizumab clinical trial in Shiga-toxin producing E. coli hemolytic uremic syndrome

Alexion Pharmaceuticals, Inc. and Alexion Pharma International Sàrl (APIS), announced today that the Paul-Ehrlich-Institut, Germany's healthcare regulatory body for biological products, has authorized initiation of an open-label clinical trial to investigate eculizumab as a treatment for patients with Shiga-toxin producing E. coli hemolytic uremic syndrome, which has resulted from infections by Enterohemorrhagic Escherichia coli in an unusually wide outbreak in Germany that began in May.

20 Jun 2011

Women, young people more worried about EHEC bacteria outbreak in Europe

The news coverage of the deadly EHEC bacteria outbreak in Europe came as a bombshell. Ghent University (Belgium) examined 6132 reactions of Belgian newspaper readers after reading the first news reports.

17 Jun 2011

Enterologics to acquire BioBalance from NYHC

Enterologics, Inc. announced today that it is acquiring all the shares of The BioBalance Corporation and its subsidiary BioBalance LLC from New York Health Care, Inc.

17 Jun 2011

Specific lipid mixtures can overcome lethal effects of multidrug-resistant bacteria

"Super bugs," which can cause wide-spread disease and may be resistant to most, if not all, conventional antibiotics, still have their weaknesses. A team of Canadian scientists discovered that specific mixtures of antimicrobial agents presented in lipid (fatty) mixtures can significantly boost the effectiveness of those agents to kill the resistant bacteria.

17 Jun 2011

BGI releases first complete map of Germany E. coli O104:H4 genome

Building upon previous efforts producing a high-quality de novo genome assemblies of deadly 2011 E. coli O104:H4 outbreak strain, the BGI and their collaborators at the University Medical Centre Hamburg-Eppendorf have now released the first complete map of the genome and plasmids without any assembly gaps.

17 Jun 2011

University of Houston chemist develops two different materials against E. coli

A University of Houston (UH) chemist who is developing materials for detecting and repelling E. coli has published papers in two high-impact journals this month.

16 Jun 2011

Low-level antibiotic exposure may cause E. coli bacteria to develop resistance

E. coli bacteria exposed to three common antibiotics were more likely to develop antibiotic resistance following low-level antibiotic exposure than after exposure to high concentrations that would kill the bacteria or inhibit their growth, according to a timely article in Microbial Drug Resistance, a peer-reviewed journal published by Mary Ann Liebert, Inc.

15 Jun 2011

Intralytix obtains FDA, FSIS regulatory clearance for bacteriophage-based product against E. coli

Intralytix, Inc. announced today that it has completed regulatory clearance from both the Food and Drug Administration (FDA) and the United States Department of Agriculture's Food Safety and Inspection Service (FSIS) for its phage-based EcoShield food safety product, effective against E. coli O157:H7.

15 Jun 2011

GlycoVaxyn's Second Annual Science Day to highlight challenges of vaccine industry

GlycoVaxyn AG, a leader in the development of conjugate vaccines, today announced that it will host its Second Annual Science Day to discuss challenges and opportunities in vaccine development on June 16-17, 2011, in Cannes, France.

15 Jun 2011

Number of E. coli deaths in Germany reaches 35, authorities say

"Four more people have died in Germany, health officials said Sunday, bringing the total number of deaths from an E. coli outbreak to 35," CNN reports. As of Sunday, 3,256 had been infected with E. coli and 812 of those have the severe form of the disease, according to the European Centre for Disease Prevention and Control, the news agency notes.

14 Jun 2011

German officials again claim sprouts as source of E. coli outbreak

"After days of confusion, German authorities finally concluded on Friday that an E. coli infection, which has claimed at least 29 lives, unsettled the nation and thrown European agriculture into disarray, had been caused by contaminated bean sprouts and not, as first was feared, by other produce," the New York Times reports.

13 Jun 2011

National, continental health center coordination lacking in E. coli outbreak response

During the handling of the E. coli outbreak in Germany, "coordination of the German public health response seems to have been utterly absent," a Lancet editorial states, adding, "But one should also ask: where was the European Centres of Disease Prevention and Control? … From the public's point of view, no visible collaboration seems to have taken place."

13 Jun 2011

Free access to enteric pathogen's genetic regulation data

Just a few genes make enterohaemorrhagic E. coli (EHEC) extremely dangerous to humans. If it were not for these genes, EHEC would hardly differ from harmless enteric bacteria. Bioinformatics scientists from the Saarbr-cken Cluster of Excellence want to exploit this similarity to find starting points for effective drugs against the EHEC pathogen.

10 Jun 2011

Viewpoints: Sebelius on medical errors; Lieberman on Medicare; The Massachusetts track record

There is no doubt that America has the world's most skilled doctors and nurses and its finest hospitals. Every day, many Americans receive care that is as good as or better than any in the world. But far too often, we fall short of that high standard when good people get trapped in flawed systems (Kathleen Sebelius and Sue Currin, 6/10).

10 Jun 2011

German hospital adopts Luminex new diagnostic assay to manage current E.coli outbreak

Luminex Corporation and the Kliniken der Stadt Koln, Institute of Pathology and Institute for Hygiene today announced that Luminex's newly released xTAG Gastrointestinal Pathogen Panel (GPP) is being used successfully as a first-line screen for patients at Kliniken der Stadt Koln suspected of having an E. coli infection.

From Luminex 10 Jun 2011

Pall's GeneDisc System helps German authorities screen for deadly E.coli strain

Pall Corporation's GeneDisc System is helping German authorities screen for a deadly strain of E.coli that has sickened nearly 3000 people and disrupted that nation's food industry. Pall's GeneDisc technology is being used by Germany's national reference laboratory to expedite testing of food samples for the toxic strain of the pathogen known as E.coli O104:H4.

From Pall Corporation 10 Jun 2011

Number of new E. coli cases abating but more deaths expected

"Germany reported two more deaths and 300 more E. coli cases Wednesday, but its health minister insisted that new infections were dropping, giving some hope that the world's deadliest E. coli outbreak was abating," Associated Press reports.

9 Jun 2011

Food poisoning with E coli low but Salmonella high

According to public health officials this Tuesday, progress has been made in combating the microbes behind 50 million yearly U.S. food poisoning cases. These affect one in six Americans. This comes from the newest federal FoodNet report from the Centers for Disease Control and Prevention that shows that total food-borne illnesses dropped by nearly a quarter in the last decade and a half, but salmonella infections have steadily refused to drop, climbing slightly in recent years.

8 Jun 2011

Health officials rule out sprouts as source of German E. coli outbreak

Health officials in Germany are continuing to search for the source of an E. coli outbreak after tests on suspected sprouts from a farm in the north of the country came back negative, Deutsche Welle reports. The outbreak has killed 22 people and sickened more than 2,000 (Hallam/Penfold, 6/6).

8 Jun 2011

BGI releases third version of assembled E. coli O104 genome

Scientists worldwide have been working on the publicly available genomic sequences of the deadly E. coli O104 strain, which is causing the current health crisis in Germany and now spreading throughout Europe. To continue to speed the ongoing international efforts of researchers to assess and halt this growing epidemic, BGI and their collaborators at the University Medical Centre Hamburg-Eppendorf have now released their third version of the assembled genome, which includes new data from this E. coli O104.

8 Jun 2011