E. coli Nissle News and Research

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UC researchers engineer new probiotic to target and break down cancer cell defenses

Bacteria generally have a bad reputation, as people first think of certain strains that can cause serious illnesses like pneumonia or meningitis. However, there are many helpful bacteria, known as probiotics, that assist the body in different ways.

21 Nov 2021

Genetically engineered bacteria can monitor health from within

That feeling in your gut? Well, it's in your head, but some of it does truly start in the gastrointestinal tract.

12 Nov 2021

Sequentia collaborated with Nextbiomics to obtain a novel immunization model against COVID-19

Sequentia Biotech and NextBiomics announced the filing of a patent application for a bacterial vaccine against the COVID-19 syndrome.

From Sequentia Biotech 19 May 2021

Study: E. coli Nissle may also protect human cells against other pathogenic strains

Typically, there aren't a lot of positive thoughts when E. coli, generally found in animal and human intestines, is mentioned. It's been blamed for closing beaches and swimming pools and shuttering restaurants because of contamination in salad bars, meats or other food items.

8 Jul 2020

Journal publication supports Synlogic’s first clinical immuno-oncology program, SYNB1891

Synlogic, Inc., a clinical-stage company applying synthetic biology to beneficial microbes to develop novel, living medicines, today announced the publication in Nature Communications of preclinical data supporting its first clinical immuno-oncology program, SYNB1891, which is being evaluated in Phase 1 clinical trial in patients with advanced solid tumors or lymphoma.

2 Jun 2020

Researchers engineer probiotics to safely deliver immunotherapies to tumors

Researchers at Columbia Engineering have engineered probiotics to safely deliver immunotherapies within tumors.

12 Feb 2020

Genetically engineered living hydrogel material facilitates intestinal wound healing

About 1.6 million people in the US alone currently have lifelong and incurable Inflammatory Bowel Disease (IBD) including Crohn's disease and ulcerative colitis, and 70,000 new cases are diagnosed in the USA each year.

6 Dec 2019

Scientists develop genetically engineered probiotic that targets and kills cancer cells in the gut

A new study has identified a way to turn a humble cocktail of bacteria and vegetables into a targeted system that finds and kills colorectal cancer cells.

11 Jan 2018

Research provides new insight into how coevolution could shape microbial diversity in human gut

What drives bacterial strain diversity in the gut? Although there are a number of possible explanations, a recent opinion piece published in TRENDs in Microbiology by Dr Pauline Scanlan, a Royal Society - Science Foundation Ireland Research Fellow at the APC Microbiome Institute, University College Cork, addresses one potentially important and overlooked aspect of this unresolved question.

28 Mar 2017

Genetically-programmed probiotics could help detect liver cancer metastases early-on

Scientists at the University of California, San Diego and the Massachusetts Institute of Technology have described a new method for detecting liver cancer metastases in mice. The approach uses over-the-counter probiotics genetically programmed to produce signals easily detectable in urine when liver cancer metastases are present.

2 Jun 2015