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Gene therapy reduces hearing loss associated with Norrie disease in mice

An international team led by researchers at UCL and the NIHR Great Ormond Street Hospital Biomedical Research Centre have developed in mice a gene therapy that significantly reduces the hearing loss associated with Norrie disease.

29 Aug 2023

Influenza and pneumonia vaccinations associated with reduced risk of Alzheimer’s disease

Flu (influenza) and pneumonia vaccinations are associated with reduced risk of Alzheimer’s disease, according to new research reported at the Alzheimer’s Association International Conference (AAIC) 2020.

28 Aug 2023

Ciliopathies: A new understanding of the role of the NSL complex

The non-specific lethal (NSL) complex is a chromatin-associated factor that has been shown to regulate the expression of thousands of genes in both fruit flies and mammals.

25 Aug 2023

Cholesterol loss in inner ear linked to age-related hearing loss

Researchers led by María Eugenia Gomez-Casati, the Institute of Pharmacology, School of Medicine, University of Buenos Aires-CONICET; Mauricio Martin, the Institute of Medical Research Mercedes; and Martín Ferreyra, (INIMEC-CONICET-UNC), National University of Córdoba in Argentina report that age-related hearing loss is associated with a decrease of cholesterol in the inner ear.

24 Aug 2023

Asian Americans have the highest PFAS exposure, study finds

Asian Americans have significantly higher exposure than other ethnic or racial groups to PFAS, a family of thousands of synthetic chemicals also known as "toxic forever" chemicals, Mount Sinai-led researchers report.

24 Aug 2023

Study finds no link between short-term immunosuppressant use and cancer

Relatively short-term use of immunosuppressant medications to control an inflammatory disease was not associated with an increased risk of later developing cancer, according to new research led by scientists at the University of Pittsburgh and Mass Eye and Ear, a member of the Mass General Brigham health care system, and published today in the journal BMJ Oncology.

21 Aug 2023

Phase I trial shows positive results for stem cell treatment in patients with major cornea injuries

A team led by researchers from Mass Eye and Ear, a member of Mass General Brigham, reports the results of a phase I trial of a revolutionary stem cell treatment called cultivated autologous limbal epithelial cell transplantation (CALEC), which was found to be safe and well-tolerated over the short term in four patients with significant chemical burns in one eye.

18 Aug 2023

Cleveland Clinic London performs first augmented reality-assisted total knee replacement

Cleveland Clinic London is the first hospital in London to successfully perform a total knee replacement procedure with the assistance of an augmented reality-based surgical platform that was designed with artificial intelligence and machine learning.

18 Aug 2023

Prior vaccinations may help protect against Alzheimer's disease

Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer's disease, according to new research from UTHealth Houston.

16 Aug 2023

Study finds way to reverse gene silencing in inner ear cells

A deafened adult cannot recover the ability to hear, because the sensory hearing cells of the inner ear don't regenerate after damage.

14 Aug 2023

Personalized exercise testing may be more effective for fat loss

The best heart rate for burning fat differs for each individual and often does not align with the "fat burning zone" on commercial exercise machines, Icahn School of Medicine at Mount Sinai researchers report.

11 Aug 2023

3D analysis of inner ear provides insights into Ménière's disease

Elaborate 3D analysis of the inner ear now, for the first time, provide insights into volume changes of special structures in sufferers of the so-called Ménière's disease.

7 Aug 2023

Researchers discover cause of cholesteatomas

Chronic inflammation of the middle ear can cause several problems and complications that can affect a person's hearing and balance.

3 Aug 2023

UCSF Medical Center named to Honor Roll of nation's top hospitals

U.S. News & World Report ranks UCSF Health adult care among nation's top 10 hospitals in 7 specialties, Best in the West for neurology/neurosurgery and rheumatology.

1 Aug 2023

$11.5 million award renewal from NIH supports study of how stress influences cardiovascular health

Psychosocial stress profoundly affects people's lives globally, not least because it can be a critical risk factor for cardiovascular disease.

31 Jul 2023

Tobacco dependence more likely in cigarette smokers, study reveals

Cigarette smokers have higher odds of tobacco dependence than those who vape or use a variety of types of tobacco products, according to a Mount Sinai study published in July in Nicotine & Tobacco Research.

27 Jul 2023

Mammary fat tissue plays a more active role in breast biology than previously thought

An Icahn School of Medicine at Mount Sinai study sheds light on the intricate interplay between mammary adipose (fat) tissue and breast health, and offers exciting possibilities for understanding breast development, lactation, cancer, and obesity and related metabolic disorders.

26 Jul 2023

Dietary omega-3 fatty acids may protect against age-related hearing loss

Researchers report that blood levels of the omega-3 fatty acid docosahexaenoic acid (DHA) were inversely correlated with hearing difficulty in a new population-based cross-sectional study.

24 Jul 2023

Fathers' mental illness linked to increased risk of preterm birth

Babies are more likely to be born prematurely when either their father or mother has had a psychiatric diagnosis, according to a study conducted by researchers at the Icahn School of Medicine at Mount Sinai and the Karolinska Institutet and published July 20 in the open access journal PLOS Medicine.

21 Jul 2023

New method could make post-stroke motor rehabilitation more effective and affordable

The longest nerve in the human body starts in the brain and meanders its way down the neck and into the chest, where it splits into separate branches, winding its twisting tendrils to touch each internal organ.

19 Jul 2023