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Researchers identify protein that affects production of extracellular vesicles

Researchers at NYU Langone Medical Center have discovered a protein called TAT-5 that affects the production of extracellular vesicles, small sacs of membrane released from the surface of cells, capable of sending signals to other cells.

17 Nov 2011

Hemoglobin levels, blood pressure and male gender linked to higher risk of silent strokes in SCA children

Factors such as low hemoglobin levels, increased systolic blood pressure, and male gender are linked to a higher risk of silent cerebral infarcts (SCIs), or silent strokes, in children with sickle cell anemia (SCA), according to results from a large, first-of-its-kind study published online today in Blood, the Journal of the American Society of Hematology (ASH).

17 Nov 2011

MammaCare technology sets standards for clinical breast exams

MammaCare, a revolutionary tool that has set standards for teaching women and clinicians how to perform clinical breast exams, is training professionals around the country to detect lumps earlier and save lives.

17 Nov 2011

Study highlights gaps in policy and research on LGBT older adults

The National Academy on an Aging Society and Services and Advocacy for GLBT Elders (SAGE) today released the first-ever issue of the acclaimed Public Policy & Aging Report (PPAR) on lesbian, gay, bisexual, and transgender (LGBT) aging, highlighting gaps in policy and research on LGBT older adults, and current and future solutions to address the needs of LGBT elders.

17 Nov 2011

Novel program aims to improve nutrition, physical activity among young children and prevent obesity

A Kansas State University research group is jumping ahead to improve nutrition and physical activity among young children and prevent childhood obesity.

17 Nov 2011

Optimal approach to treat patients without known coronary disease much less clear

In a contemporary cohort of acute heart attack patients, 70 percent of the patients were unaware they had coronary heart disease (CHD) prior to the event and 60 percent of those patients were women or young men.

17 Nov 2011

Psoriasis may alter cholesterol composition and decrease HDL function

Collaborative research from Perelman School of Medicine at the University of Pennsylvania has shown that psoriasis patients have an increased risk of heart attack, stroke and cardiovascular death, especially if the psoriasis is moderate to severe. Now, Penn researchers have discovered the potential underlying mechanism by which the inflammatory skin disease impacts cardiovascular health.

17 Nov 2011

Researchers discover a factor in synapse-building and pruning

Like a gardener who stakes some plants and weeds out others, the brain is constantly building networks of synapses, while pruning out redundant or unneeded synapses. Researchers at The Jackson Laboratory led by Assistant Professor Zhong-wei Zhang, Ph.D., have discovered a factor in synapse-building, also showing that the building and pruning processes occur independent of each other.

17 Nov 2011

Research into role of insulin in obesity-related cancers

Niyati Parekh, an assistant professor at New York University's Steinhardt School of Culture, Education, and Human Development, has received a $720,000 Research Scholar Grant from the American Cancer Society to study the role of insulin in obesity-related cancers.

17 Nov 2011

New blood spot analysis method can diagnose range of clinical conditions

Scientists have developed a rapid method that can be used to simultaneously screen patients for a range of genetic and acquired clinical conditions from a single dried blood spot.

17 Nov 2011

Aurora kinase inhibitor may treat neuroendocrine prostate cancer

An international team of researchers led by clinicians at Weill Cornell Medical College have discovered a genetic Achilles' heel in an aggressive type of prostate cancer -- a vulnerability they say can be attacked by a targeted drug that is already in clinical trials to treat other types of cancers.

17 Nov 2011

NYU Langone recognized as leading cardiovascular hospital in the U.S.

NYU Langone Medical Center has been recognized as a leading cardiovascular hospital in the United States. The medical center received the Thomson Reuters Top 50 Cardiovascular Hospitals 2012 Award for its high-quality cardiovascular care and excellent performance in key clinical measures. The medical center is the only hospital in New York State to be honored with this year's award.

17 Nov 2011

IAC executive director wins ECBT Immunization Leadership Award

The Immunization Action Coalition (IAC) is proud to announce that its executive director, Deborah Wexler, MD, has been selected as the honoree of the Every Child By Two Immunization Leadership Award. Every Child By Two (ECBT), founded by former First Lady Rosalynn Carter and former First Lady of Arkansas Betty Bumpers, is dedicated to protecting all children from vaccine-preventable diseases.

17 Nov 2011

Male breast cancer patients report tamoxifen side effects

About half of male breast cancer patients who take the drug tamoxifen to prevent their disease from returning report side effects such as weight gain and sexual dysfunction, which prompts more than 20 percent of them to discontinue treatment, according to researchers at The University of Texas MD Anderson Cancer Center.

17 Nov 2011

TNF inhibitors may minimally increase risk of serious infections

Biologic drugs have revolutionized treatment of autoimmune diseases during the past decade despite belief there is an increased risk for serious infections from using them. But new research from the University of Alabama at Birmingham Center for Education and Research on Therapeutics reveals that a class of biologics called tumor necrosis factor antagonists, or TNF inhibitors, may only minimally increase risk compared to more traditional therapies.

17 Nov 2011

WSU researchers to study novel antibiotic that may treat VRE infection

The bacteria Enterococcus can cause infections that typically target the digestive tract or bowel; if the bacteria spread, an abdominal abscess or urinary infection could result. Enterococcus also can invade the bloodstream, leading to meningitis, pneumonia or endocarditis - an infection of the heart valve.

17 Nov 2011

Avraham raises $3M to advance ladostigil Phase II Alzheimer's trial

The drug, ladostigil, is a molecule that combines components from the existing drugs Azilect and Exelon. Teva's Azilect, for the treatment of Parkinson's disease, was developed by Prof. Emeritus Moussa Youdim of the Technion-Israel Institute of Technology. Azilect is the only anti-Parkinson's drug that has proven to have a disease-modifying effect. Novartis's Exelon was developed by Prof. Marta Weinstock-Rosin of Hebrew University to treat Alzheimer's disease.

17 Nov 2011

Cancer cells tap into natural recycling system to obtain energy

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered that cancer cells tap into a natural recycling system to obtain the energy they need to keep dividing. In a study with potential implications for cancer treatments, Einstein researchers used genetic manipulation to turn off this recycling system within the walls of cells and stop both tumor growth and metastasis.

17 Nov 2011

UT Dallas students and faculty win three ASHA competitive awards

UT Dallas students and faculty have won three competitive awards from the American Speech Language and Hearing Association (ASHA), which will present the prizes at its annual conference this week in San Diego.

17 Nov 2011

New AAOS guideline on 'The Treatment of Supracondylar Humerus Fractures'

The American Academy of Orthopaedic Surgeons (AAOS) Board of Directors has recently approved and released an evidence-based clinical practice guideline (CPG) on "The Treatment of Supracondylar Humerus Fractures."

17 Nov 2011