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Ohio State study reveals bacterial defense mechanism against phages

One of the many secrets to bacteria's success is their ability to defend themselves from viruses, called phages, that infect bacteria and use their cellular machinery to make copies of themselves.

26 Apr 2024

New research lays foundation for targeted therapies to inhibit NF-κB activation

A new paper by Dana-Farber Cancer Institute scientists lays the foundation for targeted therapies to inhibit activation of nuclear factor kappa B (NF-κB), a transcription factor that plays a role in various autoimmune and inflammatory diseases and cancers.

25 Apr 2024

Giant virus takes down deadly brain parasite

The single-celled organism Naegleria fowleri ranks among the deadliest human parasites. Researchers around Matthias Horn and Patrick Arthofer from the Center for Microbiology and Environmental Systems Science at the University of Vienna, in an international collaboration, have discovered viruses that infect this harmful microbe.

24 Apr 2024

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

A new $4.8 million grant will support researchers from Indiana University School of Medicine and the Medical Research Council Laboratory of Molecular Biology to study how human neurodegenerative diseases are affected by the misfolding of the protein TDP-43.

23 Apr 2024

New vaccine promises broad protection against SARS-CoV-2 and other sarbecoviruses

Researchers at Georgia Tech and the University of Wisconsin have created a broad-spectrum vaccine capable of defending against various SARS-CoV-2 variants and related bat coronaviruses.

17 Apr 2024

Novel antibacterial discovery: Umbrella toxin particles secreted by Streptomyces

Researchers have discovered toxic protein particles, shaped like umbrellas, that soil bacteria known as Streptomyces secrete to squelch competitors, especially others of their own species.

17 Apr 2024

Study reveals structural dynamics of key hearing receptor

Professor Yunje Cho's research team from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH, Republic of Korea) has collaborated with Professor Kwang Pyo Kim's group from the Department of Applied Chemistry at Kyung Hee University (KHU, ROK), Professor Vsevolod Katritch's team from the University of Southern California (USC, USA), and Professor Carol V. Robinson from the University of Oxford (UK) to uncover the mysteries surrounding a specific receptor protein associated with hearing.

15 Apr 2024

Childhood traumatic experiences may get "under the skin" later in life

A University of Michigan study has shown that traumatic experiences during childhood may get "under the skin" later in life, impairing the muscle function of people as they age.

15 Apr 2024

Texas A&M scientists elucidate how phages disarm antibiotic-resistant bacteria

Bacterial infections pose significant challenges to agriculture and medicine, especially as cases of antibiotic-resistant bacteria continue to rise.

15 Apr 2024

Deciphering the molecular interactions of opioid receptors: Implications for drug design

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl.

13 Apr 2024

Study reveals how DNA gyrase resolves DNA entanglements

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone.

12 Apr 2024

CMS121 holds promise for treating metabolic diseases

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 6, entitled, "CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction."

9 Apr 2024

Innovative approach to disrupt misfolding of tau proteins in neurodegenerative diseases

A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, misfolded tau proteins in the brain.

3 Apr 2024

Novel antibiotic-infused hydrogel kills bacteria and promotes cell growth

Hydrogels are popular for use in skin ailments and tissue engineering. These polymer-based biocompatible materials are useful for their abilities to retain water, deliver drugs into wounds, and biodegrade.

2 Apr 2024

New insights into gas vesicle clustering in bacteria open doors for biomedical applications

Gas vesicles are hollow structures made of protein found in the cells of certain microorganisms, and researchers at Rice University believe they can be programmed for use in biomedical applications.

29 Mar 2024

Study reveals protein structure similarities in Alzheimer's and Down syndrome

More than 90% of people with Down syndrome, the most common chromosomal disorder in humans and the most frequent genetic cause of intellectual disability, are diagnosed with Alzheimer's disease by ages 55-60.

29 Mar 2024

Edible flowers bloom with health benefits

Study analyzes the bioactive compounds, antioxidant activities, and aroma profiles of four edible flowers, contributing to their nutritional and health value understanding.

22 Mar 2024

Nano-sized toxic metals found in cannabis vaping liquids even before the first use

Vapes have often been heralded as a "safer" way to consume either nicotine or cannabis, where legal to do so.

19 Mar 2024

Metformin boosts appetite-suppressing metabolite, new study finds

Metformin treatment boosts levels of Lac-Phe, an appetite-suppressing metabolite, potentially offering new insights into its mechanism and opening doors for obesity treatments.

19 Mar 2024

Piggybacking the glucose sensor technology to build universal drug monitoring system

Rice University synthetic biologists have found a way to piggyback on the glucose monitoring technology used in automated insulin dosing systems and make it universally applicable for the monitoring and dosing of virtually any drug.

15 Mar 2024

Electron News and Research

Ohio State study reveals bacterial defense mechanism against phages

New research lays foundation for targeted therapies to inhibit NF-κB activation

Giant virus takes down deadly brain parasite

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

New vaccine promises broad protection against SARS-CoV-2 and other sarbecoviruses

Novel antibacterial discovery: Umbrella toxin particles secreted by Streptomyces

Study reveals structural dynamics of key hearing receptor

Childhood traumatic experiences may get "under the skin" later in life

Texas A&M scientists elucidate how phages disarm antibiotic-resistant bacteria

Deciphering the molecular interactions of opioid receptors: Implications for drug design

Study reveals how DNA gyrase resolves DNA entanglements

CMS121 holds promise for treating metabolic diseases

Innovative approach to disrupt misfolding of tau proteins in neurodegenerative diseases

Novel antibiotic-infused hydrogel kills bacteria and promotes cell growth

New insights into gas vesicle clustering in bacteria open doors for biomedical applications

Study reveals protein structure similarities in Alzheimer's and Down syndrome

Edible flowers bloom with health benefits

Nano-sized toxic metals found in cannabis vaping liquids even before the first use

Metformin boosts appetite-suppressing metabolite, new study finds

Piggybacking the glucose sensor technology to build universal drug monitoring system

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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