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Scientists uncover a key property needed for CELMoD drugs to be effective

Scientists at Scripps Research have uncovered a critical feature that a promising new class of cancer drugs, known as CELMoDs, needs to be effective.

3 Nov 2022

Study sheds new light on how reproduction permanently alters females’ bones

Reproduction permanently alters females' bones in ways not previously known, a team of anthropologists has found. Its discovery, based on an analysis of primates, sheds new light on how giving birth can permanently change the body.

2 Nov 2022

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Researchers demonstrated how interferon-stimulated gene 15 (ISG15) is involved in the Vaccinia virus (VACV) dissemination.

1 Nov 2022

SpyCatcher-SpyTag technology used to develop recombinant protein-based intranasal vaccine against SARS-CoV-2

The findings of a new study showed that the intranasal SpyCage vaccine platform can be protective against SARS-CoV-2 and may prove to be a versatile and adaptable modality for the formulation of intranasal vaccines that target respiratory pathogens.

31 Oct 2022

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, an international team of researchers leveraged the human light chain apoferritin protomer-derived MULTI-specific, multi-Affinity antibody (Multabody, MB) platform for the generation of broad and potent SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)-neutralizing antibodies (Abs).

27 Oct 2022

Study shows the potential of experimental monoclonal antibodies to treat Epstein-Barr virus infection

A panel of investigational monoclonal antibodies (mAbs) targeting different sites of the Epstein-Barr virus (EBV) blocked infection when tested in human cells in a laboratory setting.

27 Oct 2022

Monoclonal antibodies generated from COVID-19-recovered individuals shed light on the molecular basis of SARS-CoV-2 Omicron variant immune evasion

Researchers reported three human monoclonal antibodies generated from COVID-19-recovered individuals during the initial wave of the pandemic in India.

27 Oct 2022

Study provides a guide to neutralizing Lassa virus using a trio of rare antibodies

A new study from scientists at La Jolla Institute for Immunology (LJI) gives researchers a guide to neutralizing Lassa virus using a trio of rare antibodies isolated from survivors of Lassa virus infection.

26 Oct 2022

Study shows hybrid immunity or vaccine boosters elicit plasma neutralizing activity against Omicron sublineages

Researchers evaluated imprinted antibody responses against SARS-CoV-2 Omicron sublineages.

24 Oct 2022

Scientists map structure of the hepatitis C virus E1E2 glycoprotein complex

A team led by scientists at Scripps Research and the University of Amsterdam has achieved an important goal in virology: mapping, at high resolution, critical proteins that stud the surface of the Hepatitis C virus (HCV) and enable it to enter host cells.

20 Oct 2022

Penn State researchers lay the foundation for precision fabrication of tumor models

Researchers at Penn State have successfully 3D bioprinted breast cancer tumors and treated them in a breakthrough study to better understand the disease that is one of the leading causes of mortality worldwide.

18 Oct 2022

Scientists reveal the architecture of the inner ear responsible for hearing

Scientists at Oregon Health & Science University have revealed, for the first time and in near-atomic detail, the structure of the key part of the inner ear responsible for hearing.

12 Oct 2022

The ability of antiviral formulation ViruSAL to inhibit SARS-CoV-2 infectivity

Researchers from Ireland used human bronchial epithelium models to evaluate the ability of a novel proprietary formulation called ViruSAL to inhibit SARS-CoV-2 infections.

12 Oct 2022

Transient cell-in-cell formation by tumor cells found to build resistance to immunotherapy

Researchers demonstrated that tumor cells evade immunotherapy by generating unique transient cell-in-cell structures, resistant to chemotherapy and destruction by T cells.

5 Oct 2022

Antibody escape mutations of SARS-CoV-2 BA.2.75

A new study discusses how immune escape mutations allow a recent SARS-CoV-2 variant to evade neutralizing antibodies and cause breakthrough infections.

4 Oct 2022

New cell-free protein crystallization method: A major headway in the field of structural biology

The new cell-free protein crystallization (CFPC) method developed by Tokyo Tech includes direct protein crystallization and is a major headway in the field of structural biology.

3 Oct 2022

UVA researchers solve a decades-old mystery about how bacteria can move

University of Virginia School of Medicine researchers and their collaborators have solved a decades-old mystery about how E. coli and other bacteria are able to move.

27 Sep 2022

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

Researchers presented the direct plasmid transfection method for SARS-CoV-2 virus-like particle production in insect cells and applied the VLPs to evaluate the efficacy of monoclonal antibodies and vaccinated donor sera.

26 Sep 2022

All SARS-CoV-2 variants blocked by a simple peptide with nanomolar neutralizing efficacy

In a recent study published in the journal PNAS, researchers from Finland and the United States reported a novel heptad repeat 2 (HR2) peptide that inhibited severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) without any chemical modifications.

21 Sep 2022

Virology of the human monkeypox virus

A new review to be posted in the Virus Research journal aims to provide an overview of the recent advances reported concerning hMPXV virology.

21 Sep 2022

Electron Microscopy News and Research

Scientists uncover a key property needed for CELMoD drugs to be effective

Study sheds new light on how reproduction permanently alters females’ bones

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

SpyCatcher-SpyTag technology used to develop recombinant protein-based intranasal vaccine against SARS-CoV-2

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

Study shows the potential of experimental monoclonal antibodies to treat Epstein-Barr virus infection

Monoclonal antibodies generated from COVID-19-recovered individuals shed light on the molecular basis of SARS-CoV-2 Omicron variant immune evasion

Study provides a guide to neutralizing Lassa virus using a trio of rare antibodies

Study shows hybrid immunity or vaccine boosters elicit plasma neutralizing activity against Omicron sublineages

Scientists map structure of the hepatitis C virus E1E2 glycoprotein complex

Penn State researchers lay the foundation for precision fabrication of tumor models

Scientists reveal the architecture of the inner ear responsible for hearing

The ability of antiviral formulation ViruSAL to inhibit SARS-CoV-2 infectivity

Transient cell-in-cell formation by tumor cells found to build resistance to immunotherapy

Antibody escape mutations of SARS-CoV-2 BA.2.75

New cell-free protein crystallization method: A major headway in the field of structural biology

UVA researchers solve a decades-old mystery about how bacteria can move

A fast and powerful method for the production of SARS-CoV-2 virus-like particles in insect cells

All SARS-CoV-2 variants blocked by a simple peptide with nanomolar neutralizing efficacy

Virology of the human monkeypox virus

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