Electron Microscopy News and Research

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UI study leads to better understanding of signaling capacity between neurons

The fundamental process of information transfer from neuron to neuron occurs through a relay of electrical and chemical signaling at the synapse, the junction between neurons. Electrical signals, called action potentials, cause voltage-gated calcium channels on the presynaptic neuron to open.

18 Dec 2018

Inflating cells to analyze organelle structure and function

Researchers have developed a technique that enables visualization of cellular organelles at a resolution that has not previously been achievable in optical microscopy.

17 Dec 2018

Deadly combination: Drug cocktail induces cancer cell death by switching off energy supply

A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth - this was discovered by researchers from the University of Basel's Biozentrum two years ago. In a follow-up study, recently published in Cell Reports, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.

11 Dec 2018

Scientists develop new technique for identifying small molecules

A UCLA-led team of scientists has developed a new technique that will enable researchers to easily and quickly determine the structures of organic molecules using very small samples.

28 Nov 2018

Study provides new way to treat multiple sclerosis

Nerve cells stripped of their insulation can no longer carry vital information, leading to the numbness, weakness and vision problems often associated with multiple sclerosis. A new study shows an overlooked source may be able to replace that lost insulation and provide a new way to treat diseases like MS.

27 Nov 2018

Scientists transform protein interaction studies

A team of leading academics has significantly advanced a method for studying the interactions of proteins, which will transform research in this area.

23 Nov 2018

Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNA

Pushing the limits of cryo-electron microscopy, University of California, Berkeley, scientists have captured freeze-frames of the changing shape of a huge molecule, one of the body's key molecular machines, as it locks onto DNA and loads the machinery for reading the genetic code.

20 Nov 2018

Artificial bone-like substance mimics the way real bone grows at atomic level

Researchers from Chalmers University of Technology, Sweden, have discovered how our bones grow at an atomic level, showing how an unstructured mass orders itself into a perfectly arranged bone structure.

19 Nov 2018

Researchers produce 3D chemical maps of small biological samples

Scientists at the National Synchrotron Light Source II --a U.S. Department of Energy (DOE) Office of Science User Facility at DOE's Brookhaven National Laboratory--have used ultrabright x-rays to image single bacteria with higher spatial resolution than ever before.

16 Nov 2018

Researchers succeed in building protein nanotubes from tiny scaffolds

Researchers at Tokyo Institute of Technology have succeeded in constructing protein nanotubes from tiny scaffolds made by cross-linking of engineered protein crystals.

14 Nov 2018

Scientists examine FCMs containing silver nanoparticles

Because of their antimicrobial and antifungal properties, silver nanoparticles measuring between one and 100 nanometers in size, are being incorporated outside the United States into a variety of kitchen products known as food contact materials.

9 Nov 2018

New thrombolytic based on magnetite nanoparticles successfully tested on animals

New anti-thrombosis drug based on magnetite nanoparticles developed at ITMO University was successfully tested on animals. Preclinical studies conducted in terms of the project "PHARMA 2020" showed drug's high efficacy and no side effects.

9 Nov 2018

Researchers for first time view serotonin activating its receptor using high-powered microscopes

Serotonin receptors are common drug targets in the treatment of pain, gastrointestinal dysfunctions, and mood disorders yet little is known about their three-dimensional structure.

2 Nov 2018

Game-changing microscope enables UK scientists to understand amyloid structure

Scientists have used cryo-electron microscopes to generate 3D images of amyloid, showing that aggregates form long, twisted fibers.

30 Oct 2018

Cryo-electron microscopy helps study proteins responsible for amyloid-based diseases

The century old mission to understand how the proteins responsible for amyloid-based diseases such as Alzheimer's, Huntingdon's and Parkinson's work has taken major steps forward in the last 12 months, thanks to a revolution in a powerful microscopy technique used by scientists.

30 Oct 2018