Embryo News and Research

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Animal studies demonstrate safety profile of ACT's RPE cell therapy for SMD

Advanced Cell Technology, Inc. announced today that it has completed key animal studies in connection with its Phase I multicenter study using embryonic stem cell derived Retinal Pigment Epithelium (RPE) cells to treat patients with Stargardt's Macular Dystrophy (SMD), for which it filed an Investigational New Drug Application (IND) with the US Food and Drug Administration (FDA) in November. The studies demonstrated an excellent safety profile with no safety signals such as tumors or ectopic tissues.

24 Apr 2010

New on-off switches: SUMO protein silences developmental genes, SNP2 snips SUMO to allow gene expression

Deleting a gene in mouse embryos caused cardiac defects and early death, leading researchers to identify a mechanism that turns developmental genes off and on as an embryo matures, a team led by a scientist at The University of Texas M. D. Anderson Cancer Center reported today in Molecular Cell.

23 Apr 2010

New insight into mechanism regulating early mammalian development

Scientists at the Genome Institute of Singapore (GIS) have recently generated significant single cell expression data crucial for a detailed molecular understanding of mammalian development from fertilization to embryo implantation, a process known as the preimplantation period. The knowledge gained has a direct impact on clinical applications in the areas of regenerative medicine and assisted reproduction.

22 Apr 2010

eSET program produces high pregnancy rates, minimizes multiple pregnancy risks

Every year thousand of families are created with the assistance of in-vitro fertilization. Many of those newborns are twins. While some may see this as a double blessing, it is important to understand that there are many potential risks associated with multiple gestation.

16 Apr 2010

Elective single embryo transfer for Canadian women under 35 most efficacious and cost-effective option

Many Canadian couples battling infertility turn to in vitro fertilization (IVF) to have a child. In Canada, IVF is not publicly funded, making the decision on the number of embryos to be transferred more complicated than in many European countries which link funding to elective single embryo transfer (eSET).

16 Apr 2010

New research highlights adverse effects of air pollution on human reproduction

Exposure to an increased level of air pollutants, especially nitrogen dioxide, has been associated with lower likelihoods of successful pregnancy among women undergoing in vitro fertilization, according to a team of fertility researchers.

13 Apr 2010

Transgenic mouse model study confirms passage of maternal thyroid hormones to fetus

Until now there were only indirect evidence of the transfer of thyroid hormones from mother to fetus through the placenta during pregnancy. That event is very important because the maternal thyroid hormones appear to play a key role in the development of the nervous system and other organs of the fetus; so it's true that in case of maternal thyroid disease, such hypothyroidism, have a direct bearing on the unborn child with reduction, also significant, to its Q.I..

12 Apr 2010

New Guardia AccessET Curved Embryo Transfer Catheter for embryo placement

Cook Medical's Women's Health division has released the Guardia AccessET Curved Embryo Transfer Catheter, featuring Cook's patented EchoTip technology. The catheter's echogenic band allows the catheter tip to be seen more clearly under ultrasound, which can allow for more accurate embryo placement.

9 Apr 2010

ASPIRE 2010 focuses on A.R.T. issues

Infertility, defined as the failure to conceive after 12 months or more of regular, unprotected intercourse, may affect as many as 15 percent of couples around the world including Asia. Like other countries, China's infertility rate is on the rise increasing from 3 percent to 15 percent in the past 20 years. It is estimated that at least 40 million Chinese couples have difficulty in having children or are actually infertile.

7 Apr 2010

Irvine Scientific's Vit Kit- Freeze, Vit Kit- Thaw and Oil for Embryo Culture receive CE mark approval

Irvine Scientific, a leader in Assisted Reproductive Technology (ART), announced today it received CE mark approval for its Vit Kit®- Freeze, Vit Kit®- Thaw and Oil for Embryo Culture. This news accompanies the recent announcement of CE mark approval for a number of other media for ART from Irvine Scientific.

30 Mar 2010

Cook Medical's new IVF culture-oil purification process reduces contaminant trace to below detectable limits

A new purification process developed by Cook Medical for culture oil used in assisted reproduction eliminates traces of contaminants below detectable limits of 0.1 parts per million. The oil is purified by a proprietary refining technique that removes hydrocarbon impurities, which can have adverse effects on fertilization and threaten the viability of the developing embryos. The culture oil viscosity, MEA and LAL parameters remain unchanged.

27 Mar 2010

Researchers find retinoic acid regulates SHF tissue formation

Researchers at the Keck School of Medicine of the University of Southern California have identified a key cellular mechanism that guides embryonic heart tissue formation-a process which, if disrupted, can lead to a number of common congenital heart defects.

18 Mar 2010

Study provides new perspective on cell movements

When cells move about in the body, they follow a complex pattern similar to that which amoebae and bacteria use when searching for food, a team of Vanderbilt researchers have found.

17 Mar 2010

FDA approves Irvine Scientific's Vit Kit-Freeze and Vit Kit-Thaw for cryopreservation of all stages of embryos

Irvine Scientific, a pioneer in developing products specifically for the Assisted Reproductive Technology (ART) community, announced today that the U.S. Food and Drug Administration (FDA) has approved their products intended for vitrification of pronuclear (PN) zygotes through day 3 cleavage and blastocyst stage embryos within the fertility area.

16 Mar 2010

Researchers gain new understanding of cilial protein Arl13b in Joubert syndrome

Researchers in Ireland have gained new understanding of the role played by the cilial protein Arl13b in Joubert syndrome (JS), a rare disorder characterized by developmental delay, mental retardation, and low muscle tone, among other symptoms.

16 Mar 2010

Researchers identify a novel source of adult stem cells: Foreign body-induced granulation tissue

In a pioneering new study published in the journal Translational Research, Dr. Jilpa Patel and her research group at Hektoen Institute of Medicine and Cook County Hospital in Chicago have isolated and characterized adult stem cells from granulation tissue in rats. A granulation tissue is a new regenerating tissue formed in response to an inert foreign body placed in the subcutaneous tissue.

11 Mar 2010

Protein competition over MAPK provides mechanism to integrate different signals directing early embryonic development

A Princeton University-led research team has discovered that protein competition over an important enzyme provides a mechanism to integrate different signals that direct early embryonic development. The work suggests that these signals are combined long before they interact with the organism's DNA, as was previously believed, and also may inform new therapeutic strategies to fight cancer.

10 Mar 2010

Artificial periosteum heals serious bone injuries

A husband and wife research team has found a way to use the sleeve-like cover on bone to heal serious bone injuries faster and more simply than current methods. And they've developed an artificial sleeve that spurs fast healing when a car wreck, bomb blast or disease leaves too little cover.

10 Mar 2010

ZenBio to be commercial source for popular murine 3T3-L1 cell line

ZenBio announce that they will be a commercial source for the popular murine 3T3-L1 cell line, which has been fundamental in metabolic disease research for 30 years.

10 Mar 2010

Nanoparticle growing in popularity as bactericidal agent shown to be toxic to fish: Study

A nanoparticle growing in popularity as a bactericidal agent has been shown to be toxic to fish, according to a Purdue University study.

4 Mar 2010

Embryo News and Research

Animal studies demonstrate safety profile of ACT's RPE cell therapy for SMD

New on-off switches: SUMO protein silences developmental genes, SNP2 snips SUMO to allow gene expression

New insight into mechanism regulating early mammalian development

eSET program produces high pregnancy rates, minimizes multiple pregnancy risks

Elective single embryo transfer for Canadian women under 35 most efficacious and cost-effective option

New research highlights adverse effects of air pollution on human reproduction

Transgenic mouse model study confirms passage of maternal thyroid hormones to fetus

New Guardia AccessET Curved Embryo Transfer Catheter for embryo placement

ASPIRE 2010 focuses on A.R.T. issues

Irvine Scientific's Vit Kit- Freeze, Vit Kit- Thaw and Oil for Embryo Culture receive CE mark approval

Cook Medical's new IVF culture-oil purification process reduces contaminant trace to below detectable limits

Researchers find retinoic acid regulates SHF tissue formation

Study provides new perspective on cell movements

FDA approves Irvine Scientific's Vit Kit-Freeze and Vit Kit-Thaw for cryopreservation of all stages of embryos

Researchers gain new understanding of cilial protein Arl13b in Joubert syndrome

Researchers identify a novel source of adult stem cells: Foreign body-induced granulation tissue

Protein competition over MAPK provides mechanism to integrate different signals directing early embryonic development

Artificial periosteum heals serious bone injuries

ZenBio to be commercial source for popular murine 3T3-L1 cell line

Nanoparticle growing in popularity as bactericidal agent shown to be toxic to fish: Study

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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