Encephalopathy News and Research

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Study shows Sofosbuvir alleviates COVID-19-related neurological symptoms

A group of researchers has studied the effects of an antiviral drug Sofosbuvir on human brain organoids infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

2 Jun 2020

How COVID-19 affects the nervous system

A new paper published in the journal JAMA Neurology in May 2020 discusses the presentation and complications of COVID-19 with respect to the nervous system.

31 May 2020

Anosmia and changes in brain MRI in COVID-19

Even as the COVID-19 pandemic was sweeping across the world, new symptoms and clinical presentations appeared, often confusing the picture. A case report from Italy, published in the journal JAMA Neurology in May 2020, shows that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be a neurotropic virus, and may cause infection to present primarily with anosmia.

31 May 2020

Neurological complications of COVID-19: What is known so far?

Researchers at the São Leopoldo Mandic School of Medicine in Brazil have presented a review of the current data available on the neurological effects of coronavirus disease 2019 (COVID-9).

27 May 2020

Excessive blood clotting and stroke in COVID-19 patients

The coronavirus disease COVID-19 is causing excessive blood clotting and stroke in young and healthy people, a new study has found.

21 May 2020

COVID-19 may contribute to exponential growth of Parkinson's disease in future

Parkinson's disease (PD) is expected to reach over 14 million cases worldwide by 2040. As longevity increases, so does the number of persons living with PD.

12 May 2020

Repetitive head impacts for NFL players lead to increased risk of premature death

A new study published Monday in the Journal of the American Medical Association (JAMA) by researchers from the David B. Falk College of Sport and Human Dynamics at Syracuse University shows that an increase in repetitive head impacts for NFL players leads to an increased risk of premature death.

12 May 2020

Study raises questions about diagnoses of chronic traumatic encephalopathy

A postmortem exam of the brain remains the gold standard for diagnosing chronic traumatic encephalopathy, or CTE, the neurodegenerative brain disease believed to arise from repeated hits to the head.

23 Apr 2020

Landmark 30-year study describes clinical course of patients with Crigler-Najjar syndrome

A new study summarizes more than 30 years of clinical experience and describes the clinical course of 28 individuals homozygous for damaging mutations in the UGT1A1 gene who were born between 1984 and 2015 with Crigler-Najjar syndrome.

17 Apr 2020

Tracking tau protein yields insight into possible treatments for neurodegenerative diseases

In the fight against neurodegenerative diseases such as frontotemporal dementia, Alzheimer's and Chronic Traumatic Encephalopathy, the tau protein is a major culprit.

1 Apr 2020

Padded helmets, safe tackling techniques reduce head injuries in middle school football players

Middle school football players greatly reduce the chance of head injuries if they wear padded helmets and use safe tackling and blocking techniques, according to Rutgers researchers.

4 Mar 2020

New breakthrough offers hope for potential treatment of rare childhood epilepsy

Seizure disorders in babies are frightening and heartbreaking. A new basic science breakthrough offers hope for a potential treatment for rare developmental and epileptic encephalopathies resulting from a single genetic mutation.

20 Feb 2020

Live-cell imaging provides new insights into dynamic structure of mitochondria

As power plants and energy stores, mitochondria are essential components of almost all cells in plants, fungi and animals. Until now, it has been assumed that these functions underlie a static structure of mitochondrial membranes.

18 Feb 2020

Minimally invasive technique to directly measure cardiac output in newborns

The amount of blood that the heart pumps in one minute (cardiac output) can be directly measured safely in newborns by monitoring changes in blood velocity after injecting saline, indicates a paper published online Dec. 17, 2019 in the Journal of Pediatrics and Neonatal Medicine.

8 Jan 2020

Study shows the feasibility of using gene therapy to treat chronic traumatic encephalopathy

A new study shows the feasibility of using gene therapy to treat the progressive neurodegenerative disorder chronic traumatic encephalopathy.

3 Jan 2020

Study measures brain injury from boxing, MMA in younger and older fighters

For boxers and mixed martial arts (MMA) fighters, is there a safe level of exposure to head trauma? A new study shows different effects in the brain for younger, current fighters compared to older, retired fighters.

23 Dec 2019

Declining dementia rates may be due to generational differences in lifetime lead exposure

To the medical community's surprise, several studies from the US, Canada, and Europe suggest a promising downward trend in the incidence and prevalence of dementia. Important risk factors for dementia, such as mid-life obesity and mid-life diabetes, have been increasing rapidly, so the decline in dementia incidence is particularly perplexing.

19 Dec 2019

Developing brain vulnerable to HIV despite early treatment

A new study on how the HIV infection affects the development of intellect and other areas of brain development in children shows that early treatment doesn’t completely avert these negative outcomes. The paper, published in the journal Clinical Infectious Diseases shows that HIV in children can lead to impaired learning, reasoning and brain functioning.

18 Dec 2019

Researchers identify rare genetic disorder

A team of South Australian researchers has cracked a rare gene variant for a disorder that sees a normal healthy child start to lose muscle tone and motor skills, ultimately losing the capacity to walk and use language.

16 Dec 2019

DNA-modulated liquid droplets may explain how prion proteins clump

Researchers at the Federal University of Rio de Janeiro, in Brazil, have identified that the interaction between prion proteins and DNA may be behind the formation of protein amyloid aggregates and of the emergence of neurodegenerative diseases such as Creutzfeldt-Jakob disease and other spongiform encephalopathies.

22 Nov 2019