Encephalopathy News and Research

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First identification of the genetic basis of disease in a patient with a complex I assembly defect

Mitochondrial complex I deficiency is one of the most common defects in patients with mitochondrial disease. The deficiency results from a failure to assemble the enzyme properly, but the nature of the molecular chaperones that are necessary for this process in mammals have remained obscure.

3 Oct 2005

India could be the source of Mad Cow disease

According to British scientists, Mad Cow disease may have originated from animal feed contaminated with human remains washed ashore after being floated down river in Indian funerals.

5 Sep 2005

U.S. to toughen mad cow safeguards after case in Texas

The U.S. Agriculture Department (USDA) has now formally closed its investigation of the first native U.S. case of mad cow disease, in June this year.

31 Aug 2005

New method can detect 'mad cow' proteins in blood

Researchers at the University of Texas Medical Branch at Galveston (UTMB) have found a way to detect the malformed proteins in blood that cause "mad cow disease".

29 Aug 2005

Austrian authorities find mad cow disease in Slovenian cattle

The health ministry says a case of mad cow disease, or bovine spongiform encephalopathy (BSE), was found in a Slovenian animal that had been brought to the southern city of Graz to be slaughtered, but says there is no risk to consumers.

25 Aug 2005

Six possible cases of Creutzfeldt-Jakob disease in Idaho sets alarm bells ringing

According to Idaho officials one case of Creutzfeldt-Jakob disease has been confirmed, and they are investigating five other suspected cases in the state.

14 Aug 2005

Three cases of mad cow disease in UK from donated blood

Health officials in the UK are warning blood donors that three patients developed the human form of mad cow disease after receiving blood from a possible one hundred people, some of whom are suspected of carrying the deadly agent.

21 Jul 2005

'Big Gun' government official needed to oversee U.S. animal disease programs

A National Academy of Sciences panel has said this week that one high ranking government official may be the best way to consolidate U.S. animal disease oversights in order to protect consumers from mad cow disease, bird flu and other serious animal ailments that can jump species.

19 Jul 2005

Outer lining of the umbilical cord is a rich source of stem cells

CellResearch Corporation in Singapore and its team of scientists, headed by Chief Scientist, Dr Phan Toan Thang, have recently made a revolutionary discovery: that the outer lining of the umbilical cord is a rich source of stem cells.

12 Jul 2005

Pomegranate juice may help babies resist brain injuries from low oxygen

Expectant mothers at risk of premature birth may want to consider drinking pomegranate juice to help their babies resist brain injuries from low oxygen and reduced blood flow, a new mouse study from Washington University School of Medicine in St. Louis suggests.

28 Jun 2005

U.S. agriculture officials anxiously await mad cow results

After a series of conflicting test results in the U.S., last week a sample of brain matter from a cow suspected of having been infected with bovine spongiform encephalopathy (BSE), or mad cow disease, was delivered to a British government-run veterinary laboratory in Weybridge, Surrey.

20 Jun 2005

Mad cow disease found in animal in the U.S.

In disturbing news this week, Agriculture Secretary Mike Johanns said a U.S. animal has tested positive for mad cow disease.

12 Jun 2005

Research opens up new directions for studying prion diseases in humans

The mysterious, highly infectious prions, which cause the severe destruction of the brain that characterizes "mad cow disease" and several human brain degenerative disorders, can be rendered harmless in the laboratory by a slight alternation of the three-dimensional conformation or shape of the prion protein's structure.

9 Jun 2005

Genesis Bioventures signs agreement for control of Mad Cow diagnostic company

Further to a Letter of Intent previously reported, Genesis Bioventures today announced that it has entered into a binding agreement with Efoora Inc. and Prion Developmental Laboratories, Inc. to buy all of Efoora's majority interest shares owned or pledged in PDL thereby gaining controlling interest of PDL. A Form 8-K has been filed with the SEC in this regard. Prior to the Agreement, GBI had one-third equity interest in PDL.

1 Jun 2005

Premature use of stem cell therapy could put patients at risk

The premature use of stem cell therapy could put many patients at risk of viral or prion diseases unless appropriate safety systems are in place, warn experts in this week’s BMJ.

19 May 2005

First confirmed case of Mad Cow disease in Holland

The first known case of the human form of "mad cow disease" - known as variant Creutzfeldt-Jakob Disease (vCJD), has been diagnosed in the Netherlands.

22 Apr 2005

Researchers and drug giant team up to find cure for CJD

The Medical Research Council's Prion Unit, based at University College London, a leading British research group, is joining forces with drugs giant GlaxoSmithKline (GSK) to develop a cure for the disease Creutzfeldt-Jakob Disease (CJD).

12 Apr 2005

Fibril shape is the basis of prion strains and cross-species prion infection

New research on prions, the infectious proteins behind "mad cow" disease and Creutzfeld-Jakob disease in humans, suggests that the ability of prions in one species to infect other species depends on the shape of the toxic threadlike fibers produced by the prion. Two studies on the topic appear in the 8 April issue of the journal Cell.

7 Apr 2005

Diagnosis of prions in patients should utilize novel strategy, conformation-dependent immunoassay

A technique for detecting prions in tissue, developed in recent years by UCSF scientists, is significantly more sensitive than the diagnostic procedures currently used to detect the lethal particles in samples of brain tissue from patients, according to a study performed by a UCSF team.

22 Feb 2005

Prions, previously thought to accumulate mainly in the brain can also infect other organs

Prions, infectious proteins associated with bovine spongiform encephalopathy (BSE) or Mad Cow Disease, were previously thought to accumulate mainly in the brain, but Yale and University of Zurich researchers report in Science that other organs can also become infected.

7 Feb 2005