Endocrine News and Research

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Imaging PR status may help identify tumor response to endocrine therapy

Research published in the July issue of The Journal of Nuclear Medicine shows imaging progesterone receptor (PR) status also may be able to identify responders and nonresponders to endocrine therapy at an early stage.

3 Jul 2012

Link between phthalates and early eczema uncovered

Research published in Environmental Health Perspectives suggests that prenatal exposure to butylbenzyl phthalate, a common component of vinyl flooring, may increase a child’s risk for developing early eczema.

29 Jun 2012

Ovarian grafts can produce hormones for more than 7 years

Transplanting previously frozen ovarian tissue back into female cancer survivors can lead to long-term hormonal function and preservation of fertility, according to a new study by Samuel Kim from the University of Kansas Medical Center in the US. His work-, which shows that hormonal function was restored in five women 12-20 weeks after transplantation, and in one case lasted for more than seven years, appears online in the Journal of Assisted Reproduction and Genetics-, published by Springer.

29 Jun 2012

Early pain relief surgery improves long-term chronic pancreatitis outcomes

Surgery for pain relief in chronic pancreatitis should be considered at an earlier stage than current practice, suggest the results of a Dutch study.

28 Jun 2012

Prenatal exposure to PCBs impacts reproductive function in offspring

Prenatal exposure to the environmental contaminants polychlorinated biphenyls, or PCBs, causes long-term changes to the developing brain that have adverse effects on reproductive function later in life, a new study finds. Results will be presented Saturday at The Endocrine Society's 94th Annual Meeting in Houston.

28 Jun 2012

UH receives federal grants to pursue projects related to prostate cancer, diabetes and obesity

Researchers at the University of Houston (UH) have been awarded more than $862,000 in federal grants to pursue projects related to prostate cancer, diabetes and obesity. The U.S. Department of Defense (DOD) and National Institutes of Health (NIH) will fund two new prostate cancer projects, while a third NIH grant will support diabetes and obesity research in the UH Center for Nuclear Receptors and Cell Signaling (CNRCS).

28 Jun 2012

Study suggests adverse role for BclI polymorphism in obesity and insulin resistance

A large study in people at risk of diabetes has found a direct association between the presence of a small genetic alteration in a hormone receptor and increased body fat and insulin resistance. The results, to be presented Tuesday at The Endocrine Society's 94th Annual Meeting in Houston, suggest an adverse role for a previously described genetic variant, the BclI polymorphism.

28 Jun 2012

Exposure to phthalates may raise childhood obesity risk

Obese children have higher exposure to phthalates than nonobese children, suggest results presented at ENDO 2012 in Houston, Texas, USA, the annual meeting of The Endocrine Society.

27 Jun 2012

Safe vitamin D treatment without raising calcium levels

Patients with a gland disorder that causes excessive calcium in their blood who also have vitamin D deficiency can safely receive vitamin D treatment without it raising their calcium levels, a new study has determined. The results with one-year follow-up will be presented Tuesday at The Endocrine Society's 94th Annual Meeting in Houston.

27 Jun 2012

High-calorie food images stimulate brain's appetite control center

A picture may be worth a thousand calories, a new study suggests. Looking at images of high-calorie foods stimulates the brain's appetite control center and results in an increased desire for food, according to the study, which will be presented Monday at The Endocrine Society's 94th Annual Meeting in Houston.

27 Jun 2012

Obese children show greater exposure to phthalates

Obese children show greater exposure than nonobese children to a phthalate, a chemical used to soften plastics in some children's toys and many household products, according to a new study, which found that the obesity risk increases according to the level of the chemical found in the bloodstream.

27 Jun 2012

The Endocrine Society issues Statement of Principles on EDCs and public health protection

In a Statement of Principles unveiled today, The Endocrine Society proposes a streamlined definition for endocrine-disrupting chemicals (EDCs) and offers recommendations that will strengthen the ability of current screening programs to identify EDCs.

27 Jun 2012

OOM women in mid-pregnancy have reduced levels of EDCs than general population

A lifestyle that features fresh foods and limited use of products likely to contain environmental chemicals has been shown to reduce exposure to endocrine-disrupting chemicals (EDCs), such as BPA and phthalates, in a small population study. EDCs are linked to a number of adverse health complications including neuro-developmental delays, behavioral issues and fertility problems.

27 Jun 2012

Women with PCOS and sleep apnea more likely to develop prediabetes

Women with polycystic ovary syndrome (PCOS) who also have obstructive sleep apnea have at least three times the risk of having prediabetes compared with women who do not have PCOS, according to a new study.

27 Jun 2012

Prenatal exposure to BPA appears to program uterine estrogen responsiveness in adulthood

Prenatal exposure to bisphenol A, or BPA, a chemical found in many common plastic household items, can cause numerous genes in the uterus to respond differently to estrogen in adulthood, according to a study using a mouse model. The results will be presented Tuesday at The Endocrine Society's 94th Annual Meeting in Houston.

27 Jun 2012

Vitamin D and calcium supplements could increase risk of kidney stones

Calcium and vitamin D supplements are associated with high calcium levels in the blood and urine, which could increase the risk of kidney stones, a new study finds. The results will be presented Tuesday at The Endocrine Society's 94th Annual Meeting in Houston.

27 Jun 2012

Marker to identify patients who have difficulties in maintaining body weight

A pre-diet measurement of two hormones related to weight regulation can help predict which dieters will be more likely to maintain their weight loss and who will not, according to a new study. The results will be presented Sunday at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012

Ghrelin increases incentive for humans to eat high-calorie foods

A new study suggests that the appetite-inducing hormone ghrelin increases the incentive for humans to eat high-calorie foods, even on a full stomach. The results will be reported Sunday at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012

Degludec reduces risk of nighttime low blood sugar in elderly diabetic adults

A new variety of long-lasting insulin, called insulin degludec, lowers the risk of nighttime low blood sugar in elderly diabetic adults compared with insulin glargine, a systematic review of diabetes studies has found.

26 Jun 2012

LOGIC-Insulin software more effectively controls blood-sugar levels among critically ill patients

A computer-software program more effectively controlled blood-sugar levels among critically ill patients than nurse-directed care did, according to the first large clinical trial of its kind. The results will be presented at The Endocrine Society's 94th Annual Meeting in Houston.

26 Jun 2012