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Increasing marijuana-like chemicals in the brain can help correct behavioral issues related to fragile X

American and European scientists have found that increasing natural marijuana-like chemicals in the brain can help correct behavioral issues related to fragile X syndrome, the most common known genetic cause of autism.

26 Sep 2012

Newly developed technique can kill antibiotic-resistant germs

Infectious bacteria received a taste of their own medicine from University of Missouri researchers who used viruses to infect and kill colonies of Pseudomonas aeruginosa, common disease-causing bacteria. The viruses, known as bacteriophages, could be used to efficiently sanitize water treatment facilities and may aid in the fight against deadly antibiotic-resistant bacteria.

25 Sep 2012

Chronic respiratory disease treatments: an interview with Dr Sven Jan-Anders Karlsson, CEO of Verona Pharma

There are many different chronic respiratory diseases. Verona Pharma is mainly focused on two diseases: asthma and COPD. Asthma is a very common disease and unfortunately it has been increasing in prevalence in developed countries. This is the same with COPD; however, there may be different reasons for this.

25 Sep 2012

New clinical trial to evaluate DEX-M74 against hereditary inclusion body myopathy

Researchers have launched a clinical trial to evaluate the drug candidate DEX-M74 as a treatment for a rare degenerative muscle disease, hereditary inclusion body myopathy (HIBM). National Institutes of Health scientists from the National Center for Advancing Translational Sciences (NCATS) and the National Human Genome Research Institute (NHGRI) will conduct the clinical trial at the NIH Clinical Center.

25 Sep 2012

Wiley announces publication of 6-volume Encyclopedia of Drug Metabolism and Interactions

Wiley is pleased to announce publication of the state-of-the-art, 6-volume Encyclopedia of Drug Metabolism and Interactions.

25 Sep 2012

Age at onset influences juvenile dermatomyositis course

Children diagnosed with juvenile dermatomyositis at age 3 years or earlier have milder symptoms than patients with later onset, research suggests.

24 Sep 2012

Conceptually novel mechanism for biological regulation of cell suicide

Death plays a big role in keeping things alive. Consider the tightly orchestrated suicide of cells--a phenomenon essential to everything from shaping an embryo to keeping it free of cancer later in life. When cells refuse to die, and instead multiply uncontrollably, they become what we call tumors. An intricate circuitry of biochemical reactions inside cells coordinates their self-sacrifice. Tracing that circuitry is, naturally, an important part of cancer research.

24 Sep 2012

New technique allows cells to make terpenes

Scientists at The Scripps Research Institute have shown how to synthesize in the laboratory an important set of natural compounds known as terpenes. The largest class of chemicals made by living organisms, terpenes are made within cells by some of the most complex chemical reactions found in biology.

24 Sep 2012

Greenhouse-grown corn seeds could help treat lysosomal storage disease

The seeds of greenhouse-grown corn could hold the key to treating a rare, life-threatening childhood genetic disease, according to researchers from Simon Fraser University.

24 Sep 2012

Investigators identify two promising therapies to treat patients with acute megakaryocytic leukemia

Investigators at Northwestern University Feinberg School of Medicine have identified two promising therapies to treat patients with acute megakaryocytic leukemia (AMKL), a rare form of leukemia where the number of cases is expected to increase with the aging population.

21 Sep 2012

Isolating and concentrating cells from whole blood: an interview with Victor Ugaz

There are several reasons for this. One is because analysis involving different kinds of blood cells may require you to be able to separate red blood cells from white blood cells, or plasma from whole blood etc.

21 Sep 2012

Iron transport may contribute to diabetes

Scientists have been trying to explain the causes of diabetes for many years. Researchers at the University of Copenhagen and Novo Nordisk A/S have now shown that the increased activity of one particular iron-transport protein destroys insulin-producing beta cells. In addition, the new research shows that mice without this iron transporter are protected against developing diabetes.

21 Sep 2012

Cytochroma commences CTAP101 phase 3 study in secondary hyperparathyroidism

Cytochroma today announced the initiation of a phase 3 study of CTAP101 capsules in patients with secondary hyperparathyroidism (SHPT), stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency.

21 Sep 2012

GSK3 inhibition protects against gum disease

Treatment with the cell-permeable glycogen synthase kinase -3β-specific enzyme inhibitor SB216763 successfully suppresses alveolar bone loss in mice infected with the main periodontal pathogen, Porphyromonas gingivalis, report researchers.

20 Sep 2012

Study finds high levels of ESBL bacteria in Danish chicken meat

Nearly half of the samples from chicken meat imported into Denmark contain ESBL bacteria and for the first time the level is almost as high in Danish chicken meat. By contrast, the occurrence in Danish pigs has decreased significantly since farmers stopped using cephalosporins for pigs.

20 Sep 2012

Thermo Fisher Scientific announces opening of Molecular Biology Center of Excellence in Lithuania

Thermo Fisher Scientific Inc., the world leader in serving science, today announced the official opening of its Molecular Biology Center of Excellence in Vilnius, Lithuania.

From Thermo Fisher Scientific Inc. 20 Sep 2012

TECHLAB to utilize Dynex's Gold SmartKit packaging for ELISA product line

Dynex Technologies, Inc. announced today it has finalized a supply agreement with TECHLAB, Inc. (Blacksburg, VA), allowing TECHLAB to utilize Dynex's Gold SmartKit packaging for their ELISA product line.

20 Sep 2012

Abiraterone acetate confirmed to offer significant survival benefit to advanced prostate cancer patients

Results of a phase 3 trial published in The Lancet Oncology have confirmed that the drug abiraterone acetate (marketed as Zytiga®) offers a significant survival benefit to patients with castration-resistant prostate cancer, which is spreading to other parts of their body (known as metastatic prostate cancer).

18 Sep 2012

BACE2 enzyme could represent powerful new tool against Alzheimer's

An enzyme that could represent a powerful new tool for combating Alzheimer's disease has been discovered by researchers at Mayo Clinic in Florida. The enzyme - known as BACE2 - destroys beta-amyloid, a toxic protein fragment that litters the brains of patients who have the disease.

18 Sep 2012

Refinements in gene therapy prove beneficial for ‘bubble babies’

Results from a long-term study published in Blood show that adding a low dose of chemotherapy prior to gene therapy can help improve outcomes in children with adenosine deaminase-deficient severe combined immunodeficiency.

17 Sep 2012

Enzyme News and Research

Increasing marijuana-like chemicals in the brain can help correct behavioral issues related to fragile X

Newly developed technique can kill antibiotic-resistant germs

Chronic respiratory disease treatments: an interview with Dr Sven Jan-Anders Karlsson, CEO of Verona Pharma

New clinical trial to evaluate DEX-M74 against hereditary inclusion body myopathy

Wiley announces publication of 6-volume Encyclopedia of Drug Metabolism and Interactions

Age at onset influences juvenile dermatomyositis course

Conceptually novel mechanism for biological regulation of cell suicide

New technique allows cells to make terpenes

Greenhouse-grown corn seeds could help treat lysosomal storage disease

Investigators identify two promising therapies to treat patients with acute megakaryocytic leukemia

Isolating and concentrating cells from whole blood: an interview with Victor Ugaz

Iron transport may contribute to diabetes

Cytochroma commences CTAP101 phase 3 study in secondary hyperparathyroidism

GSK3 inhibition protects against gum disease

Study finds high levels of ESBL bacteria in Danish chicken meat

Thermo Fisher Scientific announces opening of Molecular Biology Center of Excellence in Lithuania

TECHLAB to utilize Dynex's Gold SmartKit packaging for ELISA product line

Abiraterone acetate confirmed to offer significant survival benefit to advanced prostate cancer patients

BACE2 enzyme could represent powerful new tool against Alzheimer's

Refinements in gene therapy prove beneficial for ‘bubble babies’

Biochemistry eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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