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Biogen, Elan announce clinical utility data of two-step ELISA to detect anti-JCV antibodies

Biogen Idec and Elan Corporation, plc today announced data further supporting the potential clinical utility of an investigational assay that detects anti-JC virus (JCV) antibodies in human plasma or serum.

18 Oct 2010

EpiMark Analysis Kit simplifies DNA methylation analysis for epigenetics researchers

New England Biolabs (NEB) has launched a suite of new and validated products designed to simplify DNA methylation analysis for epigenetics researchers. These enzyme-based solutions address some of the challenges of the current methods, including the lack of a reproducible method for the analysis and quantitation of 5-hydroxymethlcytosine (5-hmC) in the epigenome.

15 Oct 2010

Sunshine Biopharma to enter Adva-27a Phase I clinical trial for Multi-Drug Resistant breast cancer

Sunshine Biopharma, Inc. a development stage pharmaceutical company focused on the research, development and commercialization of drugs for the treatment of various forms of cancer, today announced that it issued a letter to its shareholders advising that it had filed for patent protection worldwide and expects to enter Phase I clinical trials for its principal drug, Adva-27a, beginning with GMP manufacturing and animal tox studies.

14 Oct 2010

Dyadic International receives sixth USPTO patent

Dyadic International, Inc. a global biotechnology company focused on the discovery, development, manufacture and sale of enzyme and protein products and solutions for the bioenergy, industrial enzyme and biopharmaceutical industries, announced today that it has been issued U.S. Patent No. 7,794,962 by the United States Patent and Trademark Office.

14 Oct 2010

Stimulating brain's nicotine receptors may eliminate side effects of Alzheimer's drug: Research

A team of neuroscientists has discovered important new information in the search for an effective treatment for Alzheimer's disease, the debilitating neurological disorder that afflicts more than 5.3 million Americans and is the sixth-leading cause of death in the United States. Hey-Kyoung Lee, associate professor in the University of Maryland Department of Biology, and her research team have shown that they may be able to eliminate debilitating side effects caused by a promising Alzheimer's drug by stimulating the brain's nicotine receptors.

14 Oct 2010

ERYtech Pharma, Genzyme enter collaboration to develop novel therapeutic enzyme formulation

ERYtech Pharma is pleased to announce it has signed a collaborative research agreement with Genzyme Corporation to explore the feasibility of developing a novel therapeutic enzyme formulation using ERYtech's proprietary technology.

13 Oct 2010

MTN-007 phase trial evaluates vaginal microbicide to prevent rectal transmission of HIV

Tenofovir gel, a vaginal microbicide that has shown promise for preventing HIV through vaginal sex, is being tested in a new trial looking at its safety and acceptability when used rectally. The results of the study, being led by the U.S. National Institutes of Health (NIH)-funded Microbicide Trials Network (MTN), will help determine if the gel should be evaluated further for its potential to prevent HIV among both men and women who engage in receptive anal intercourse.

13 Oct 2010

Vegetable consumption decreases risk of estrogen receptor-negative breast cancer in African-American women

Investigators from the Slone Epidemiology Center at Boston University School of Medicine (BUSM) have reported that African American women who consume more vegetables are less likely to develop estrogen receptor-negative breast cancer than women with low vegetable intake. The study results, published in the American Journal of Epidemiology, were based on data from the Black Women's Health Study (BWHS), a large follow-up study of 59,000 African American women from across the U.S. conducted by investigators at the Slone Epidemiology Center since 1995.

13 Oct 2010

Researchers find gene association between Type 2 diabetes and Alzheimer's disease progression

Mount Sinai School of Medicine researchers have found that a gene associated with the onset of Type 2 diabetes also is found at lower-than-normal levels in people with Alzheimer's disease. The research, led by Giulio Maria Pasinetti, MD, PhD, The Saunder Family Professor in Neurology, and Professor of Psychiatry and Geriatrics and Adult Development at Mount Sinai School of Medicine, was published this month in Aging Cell.

13 Oct 2010

Alkermes' VIVITROL medication for treatment of opioid dependence

Alkermes, Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved VIVITROL(naltrexone for extended-release injectable suspension) for the prevention of relapse to opioid dependence, following opioid detoxification.

13 Oct 2010

DSM, BRAIN announce strategic cooperation to develop water-soluble vitamins

DSM Nutritional Products GmbH, a subsidiary of the Dutch company Royal DSM N.V., the world's primary supplier of vitamins, carotenoids and fine chemicals and BRAIN AG, one of the leading European white biotechnology companies, announced a strategic cooperation in the biotechnological production of water-soluble vitamins.

12 Oct 2010

New combination technique improves study of protein characterization

Using a combination of high-powered computers and advanced experimental magnetic resonance data, a Florida State University biophysical chemist has developed techniques that improve the way scientists can study and predict the structure and dynamics of proteins found in the human body. His innovations could ultimately shorten the time it takes researchers to develop new, more effective drugs and better understand biomedical processes that underlie a variety of health conditions.

12 Oct 2010

New microchip technology to identify neuronal regenerators

Scientists have long sought the ability to regenerate nerve cells, or neurons, which could offer a new way to treat spinal-cord damage as well as neurological diseases such as Alzheimer's or Parkinson's. Many chemicals can regenerate neurons grown in Petri dishes in the lab, but it's difficult and time-consuming to identify those chemicals that work in live animals, which is critical for developing drugs for humans.

12 Oct 2010

Halozyme Therapeutics to advance core proprietary programs through key clinical inflection points

Halozyme Therapeutics, Inc., a biopharmaceutical company developing and commercializing products targeting the extracellular matrix, today announced a focusing of its resources on advancing its core proprietary programs through key clinical inflection points in 2011 and 2012, and supporting strategic alliances with Roche and Baxter such as validation of Halozyme's commercial scale manufacturing process to produce kilogram quantities of enzyme.

12 Oct 2010

Early cancer drug trials flawed by inconsistencies in prohibited drug lists, study finds

Researchers in Canada and France have raised concerns about substantial inconsistencies in a basic aspect of the way Phase-I and Phase-II cancer clinical trials are designed.

11 Oct 2010

'Achilles heel' for HCV infection

Scientists at the Gladstone Institute of Virology and Immunology (GIVI) have found that an enzyme associated with the storage of fat in the liver is required for the infectious activity of the hepatitis C virus (HCV). This discovery may offer a new strategy for treating the infection.

11 Oct 2010

Research reveals that fragrances can cause contact allergy

The fragrances used in many household and skincare products can cause contact allergy when exposed to oxygen in the air, reveals research from the University of Gothenburg's Faculty of Science in conjunction with the University of Gothenburg to be presented at the dermatologist conference in Gothenburg.

11 Oct 2010

Phase-II clinical trial of MLN8237 drug shows promising results for treating ovarian cancer

A drug being developed as a treatment for ovarian cancer has shown single agent activity with durable disease control in some patients in a Phase-II clinical trial, an international research group has reported.

11 Oct 2010

Discovery can lead to new approach for treating MS in early stages

A deficiency in one of the immune system's enzymes affects the severity of autoimmune diseases such as MS, and explains why the course of these diseases can vary so much. New findings give an insight into how this enzyme deficiency can be diagnosed, and could lead to new medicines, reveals a thesis from the Sahlgrenska Academy.

11 Oct 2010

Abiraterone Phase III clinical data to be presented at ESMO meeting

Attendees at next week's European Society of Medical Oncology (ESMO) meeting in Milan will be presented with top-line Phase III Clinical Trials data on Abiraterone in the treatment of castration-resistant prostate cancer.

8 Oct 2010

Enzyme News and Research

Biogen, Elan announce clinical utility data of two-step ELISA to detect anti-JCV antibodies

EpiMark Analysis Kit simplifies DNA methylation analysis for epigenetics researchers

Sunshine Biopharma to enter Adva-27a Phase I clinical trial for Multi-Drug Resistant breast cancer

Dyadic International receives sixth USPTO patent

Stimulating brain's nicotine receptors may eliminate side effects of Alzheimer's drug: Research

ERYtech Pharma, Genzyme enter collaboration to develop novel therapeutic enzyme formulation

MTN-007 phase trial evaluates vaginal microbicide to prevent rectal transmission of HIV

Vegetable consumption decreases risk of estrogen receptor-negative breast cancer in African-American women

Researchers find gene association between Type 2 diabetes and Alzheimer's disease progression

Alkermes' VIVITROL medication for treatment of opioid dependence

DSM, BRAIN announce strategic cooperation to develop water-soluble vitamins

New combination technique improves study of protein characterization

New microchip technology to identify neuronal regenerators

Halozyme Therapeutics to advance core proprietary programs through key clinical inflection points

Early cancer drug trials flawed by inconsistencies in prohibited drug lists, study finds

'Achilles heel' for HCV infection

Research reveals that fragrances can cause contact allergy

Phase-II clinical trial of MLN8237 drug shows promising results for treating ovarian cancer

Discovery can lead to new approach for treating MS in early stages

Abiraterone Phase III clinical data to be presented at ESMO meeting

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