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Gene therapy approach used in creating new arteries for older patients does not appear to cause cancer

"This result is an encouraging step along the road to new tissues for patients to replace those that have failed or have been destroyed due to trauma or disease," she said.

7 Mar 2006

Johns Hopkins scientists identify protein fragment which may lead to a simple test for multiple sclerosis

Johns Hopkins scientists report the discovery of a protein found only in cerebrospinal fluid that they say might be useful in identifying a subgroup of patients with multiple sclerosis (MS) or identifying those at risk for the debilitating autoimmune disorder.

7 Mar 2006

Simple saliva test may offer a new way to probe the consequences of caffeine coupled with stress

Using doses of caffeine equivalent to drinking one to four cups of coffee and an intense arithmetic test as stressors, Klein and her colleagues found a rise in the amount of alpha amylase, an enzyme secreted by the salivary glands, in the healthy young men who participated in the study.

7 Mar 2006

Genome signature tagging used to quickly identify and distinguish between pathogens and harmless microbes

Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have developed a new, high-throughput technique for identifying the many species of microorganisms living in an unknown "microbial community."

6 Mar 2006

The incidence, distribution, and control of tuberculosis

A reduction in tuberculosis (TB) incidence, prevalence and death rate can be achieved by 2015 in most parts of the world, with the greatest challenges occurring in Africa and Eastern Europe, according to a projection by the Stop TB Department of the World Health Organization.

1 Mar 2006

Compound found in marijuana may defend against diabetic retinopathy

A compound found in marijuana won't make you high but it may help keep your eyes healthy if you're a diabetic, researchers say.

1 Mar 2006

Why people of African descent are more vulnerable to tuberculosis infection

A team of scientists has identified a cellular mechanism that may help explain the puzzle of why people of African descent are more susceptible to tuberculosis infection and why, once infected, they develop more severe states of the disease than whites.

27 Feb 2006

Research points to a novel approach to treating serious Strep infections

Researchers at the University of California, San Diego (UCSD) School of Medicine have discovered that so-called flesh-eating "Strep" bacteria use a specific enzyme to break free of the body's immune system, a finding which could potentially lead to new treatments for serious infections in human patients.

24 Feb 2006

Scientists discover genetic profile eosinophilic esophagitis

Though many parents may never have heard of it, a severe and chronic condition called eosinophilic esophagitis (EE) is recognized by doctors as an emerging health problem for children.

24 Feb 2006

Alcoholism, smoking and genetics among Plains American Indians

Alcoholism and smoking have a high rate of co-occurrence in the general population. Yet little is known about the co-morbidity of alcoholism and smoking among American Indians.

23 Feb 2006

Removing a gene involved in repairing damaged DNA causes metabolic syndrome

Removing a gene involved in repairing damaged DNA causes mice to develop the metabolic syndrome, researchers at Oregon Health & Science University have discovered.

21 Feb 2006

Mangafodipir appears to increase the cancer-killing ability of some chemotherapy drugs

A contrast agent currently used in magnetic resonance imaging (MRI), called mangafodipir, may increase the cancer-killing ability of some chemotherapy drugs while protecting normal cells, according to a study in the Journal of the National Cancer Institute.

21 Feb 2006

New mechanism that regulates K-Ras - protein that plays an important role in cancer

Researchers have discovered a protein widely known to cause the out-of-control growth of cells can actually be manipulated to induce those cells to commit suicide, providing a novel target for the development of anti-cancer drugs, according to the results of a new study led by New York University School of Medicine researchers.

21 Feb 2006

Children given lower doses of adult drugs at risk of harmful side effects

A new study has provided the strongest and most comprehensive evidence yet of the difference between how adults and infants and children process drugs.

19 Feb 2006

GeneDesign speeds design of artificial pieces of DNA

Johns Hopkins researchers have announced the development of a Web-based, automated computer program that they say greatly simplifies the time-consuming and error-prone process of manually designing artificial pieces of DNA.

17 Feb 2006

New compound CDDO-Im protects against the development of liver cancer

Researchers have identified a new compound called CDDO-Im that protects against the development of liver cancer in laboratory animals.

17 Feb 2006

Dramatic metabolic differences in how people process drugs

A Medical College of Wisconsin study provides the strongest and most complete evidence to date of major changes occurring during human development in the types and levels of enzymes responsible for the disposition of drugs and environmental chemicals.

17 Feb 2006

Major Alzheimer's discovery

A team from the Faculty of Medicine at Universiti Laval and the research centre at CHUQ (Centre hospitalier universitaire de Quibec) has discovered a natural defence mechanism that the body deploys to combat nerve cell degeneration observed in persons with Alzheimer's disease (AD).

17 Feb 2006

Elastin fragments drive emphysema

Pulmonary emphysema is caused primarily by cigarette smoking, and the underlying cellular mechanisms are thought to involve smoke-induced activation of tissue degrading enzymes known as proteases.

16 Feb 2006

Researchers capture the electrical activity of a single sperm cell

Researchers at Children's Hospital Boston and the Howard Hughes Medical Institute have, for the first time, captured the electrical activity of a single sperm cell. The technically difficult maneuver, reported in Nature, allows the first measurement of the currents that flow across the sperm's outer membrane.

14 Feb 2006