Enzyme News and Research

RSS

Nogo protein may control the progression of Alzheimer’s disease

Researchers in the Department of Neurosciences at The Cleveland Clinic Lerner Research Institute have found that Nogo, a protein known for its ability to regulate nerve regeneration, may control the progression of Alzheimer’s disease.

3 Aug 2004

Water from the Dead Sea, the climate of Jordan and a special cream can significantly help sufferers of vitiligo

Vitiligo causes the skin to lose its colour in patches and is associated with a build-up of an oxygen-related molecule (hydrogen peroxide) in the skin. Sufferers can't fight the development of this molecule due to a shortage of an enzyme in the skin.

3 Aug 2004

Third of heart failure patients face increased risk of death because they do not receive an angiotensin-converting enzyme (ACE) inhibitor

Overwhelming evidence accumulated during almost 20 years of clinical experience has established the benefits of this drug, which blocks the harmful effects of angiotensin, a substance that causes blood vessels to narrow, said the study authors.

3 Aug 2004

Metabasis Therapeutics announces multi-center Phase 2 study to evaluate the orally administered antiviral compound remofovir mesylate

Metabasis Therapeutics has announced the initiation of a multi-center, multi- national Phase 2 study to evaluate the orally administered antiviral compound remofovir mesylate in chronic hepatitis B (HBV) infected patients.

3 Aug 2004

Switches in the brain that tell the body to stop eating and start burning calories

A Brown-led research team has discovered a pair of universal switches in the brain that tell the body to stop eating and start burning calories.

3 Aug 2004

First-of-its-kind noninvasive imaging technique shows two proteins interacting

Radiologists at Washington University School of Medicine in St. Louis have developed a first-of-its-kind noninvasive imaging technique that allows them to watch two proteins interacting in live animals.

2 Aug 2004

Scientists create mice that don't gain weight, even when fed fat-laden, high calorie diets

By altering the expression of a single -- albeit different – gene, Drs. Roger Davis (UMASS Medical School, USA) and Ying-Hue Lee (Academia Sinica, Taiwan) have succeeded in creating two different strains of transgenic mice that don't gain weight, even when fed fat-laden, high calorie diets.

2 Aug 2004

Identification of PIK3CA as an oncogene associated with brain cancers opens the door to new screening processes

Hotspots in two areas of a gene that encodes a specific signaling enzyme, or kinase, are vulnerable to a variety of mutations found in five types of brain cancers, according to a report published in the August 1 issue of the journal Cancer Research.

2 Aug 2004

Anti-hypertensive drug clonidine before non-cardiac surgery reduces risk of complications due to inadequate blood flow to the heart

Patients with or at risk for heart disease who take the anti-hypertensive drug clonidine before non-cardiac surgery can significantly reduce the risk of complications and death due to inadequate blood flow to the heart, according to a study by UCSF researchers at the San Francisco Veterans Affairs Medical Center.

29 Jul 2004

Adenosine triphosphate is a culprit in causing the devastating damage of spinal cord injury

ATP - adenosine triphosphate, the vital energy source that keeps our body’s cells alive, runs amok at the site of a spinal cord injury, pouring into the area around the wound and killing the cells that normally allow us to move, scientists report in the cover story of the August issue of Nature Medicine.

29 Jul 2004

Molecular pathway in the brain may explain why some patients suffering from inflammatory diseases develop depression

Feeling sick can be "all in the head" for people with inflammatory disorders or for those receiving immunotherapy, say Robert Dantzer and Keith Kelley, professors in the department of animal sciences at the University of Illinois at Urbana-Champaign.

29 Jul 2004

Proof of principle that it is possible to deliver new genes body-wide to all the muscles of an adult animal

MDA-supported researchers at the University of Washington-Seattle have delivered the gene for the dystrophin protein to all voluntary muscles with a single intravenous injection in mice with Duchenne muscular dystrophy (DMD).

29 Jul 2004

New process that simplifies the production of proteins

F. William Studier, a biophysicist at the U.S. Department of Energy's Brookhaven National Laboratory, has won a 2004 R&D 100 award for developing a new process that simplifies the production of proteins in the widely used T7 gene expression system.

29 Jul 2004

Researchers discover a carbohydrate with an unusual structure in the cell walls of the bacterium that causes tuberculosis

Even though we have lost much of our fear of tuberculosis in the industrialized countries, according to the WHO about 2 million people worldwide die each year of this infectious disease.

28 Jul 2004

Light-sensitive probe to help doctors spot breast cancer

A light-sensitive probe is being developed to help doctors spot breast cancer in some of the 70,000 American women each year whose malignancies fail to show up in needle biopsies.

26 Jul 2004

Gene responsible for infertility

A paper describing discoveries about the role of a gene that is important in all animals, plants, and fungi is published in the 20 July 2004 issue of the journal Proceedings of the National Academy of Sciences.

23 Jul 2004

Cancers of the gut amongst the most preventable through changes in diet

Cancers of the gut are one of the major causes of death from cancer, but a review published this week shows that they are also amongst the most preventable through changes in diet.

23 Jul 2004

Epilepsy, new therapeutic possibilities

To date epilepsy research has mainly concentrated on the transmission of the nerve cell signals to what are known as the synapses.

23 Jul 2004

ARICEPT® delays the onset of Alzheimer's among people with mild cognitive impairment

ARICEPT® a popular Alzheimer's drug has been shown to delay the onset of the disease among people with mild cognitive impairment.

19 Jul 2004

New compound that is designed to overcome Gleevec resistance

One of the truly spectacular success stories in modern oncology is the development and implementation of Gleevec, a drug that virtually halts the progress of chronic myeloid leukemia. Yet for some patients who harbor particularly stubborn genetic mutations, Gleevec fails miserably.

17 Jul 2004

Enzyme News and Research

Nogo protein may control the progression of Alzheimer’s disease

Water from the Dead Sea, the climate of Jordan and a special cream can significantly help sufferers of vitiligo

Third of heart failure patients face increased risk of death because they do not receive an angiotensin-converting enzyme (ACE) inhibitor

Metabasis Therapeutics announces multi-center Phase 2 study to evaluate the orally administered antiviral compound remofovir mesylate

Switches in the brain that tell the body to stop eating and start burning calories

First-of-its-kind noninvasive imaging technique shows two proteins interacting

Scientists create mice that don't gain weight, even when fed fat-laden, high calorie diets

Identification of PIK3CA as an oncogene associated with brain cancers opens the door to new screening processes

Anti-hypertensive drug clonidine before non-cardiac surgery reduces risk of complications due to inadequate blood flow to the heart

Adenosine triphosphate is a culprit in causing the devastating damage of spinal cord injury

Molecular pathway in the brain may explain why some patients suffering from inflammatory diseases develop depression

Proof of principle that it is possible to deliver new genes body-wide to all the muscles of an adult animal

New process that simplifies the production of proteins

Researchers discover a carbohydrate with an unusual structure in the cell walls of the bacterium that causes tuberculosis

Light-sensitive probe to help doctors spot breast cancer

Gene responsible for infertility

Cancers of the gut amongst the most preventable through changes in diet

Epilepsy, new therapeutic possibilities

ARICEPT® delays the onset of Alzheimer's among people with mild cognitive impairment

New compound that is designed to overcome Gleevec resistance

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

Latest Life Science News