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Link between hyperglycemia (high blood glucose), overexpression of PKC-beta 2 and kidney disease

Scientists at Joslin Diabetes Center have investigated PKC-beta -- a critical enzyme implicated in the devastating complications of type 1 and type 2 diabetes -- for more than two decades.

10 Jun 2005

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

Using targeted RNA interference, or RNAi libraries, researchers at Harvard Medical School describe the first large-scale classification of kinase and phosphatase gene families on the basis of their role in apoptosis and cell survival. This study appears in the June issue of Nature Cell Biology.

10 Jun 2005

New start-up to market test that predicts heart attack risk

PrognostiX, a start-up company based on Cleveland Clinic technology, has received approval from the U.S. Food and Drug Administration to begin selling a diagnostic test capable of identifying patients who are in imminent danger of heart attack or death.

9 Jun 2005

Designed drug for combined hormone and chemotherapy treatment

The search for new drugs to fight cancer remains at the top of the to do list for pharmaceutical researchers. A recent variation is polymer chemotherapy agents, drugs that have been attached to a "backbone" of long chain molecules.

9 Jun 2005

Prototype drug shows promise in slowing replication of the virus responsible for SARS

A prototype drug created by researchers at the University of Illinois at Chicago shows promise in slowing replication of the virus responsible for severe acute respiratory syndrome, or SARS.

8 Jun 2005

6 minutes exercise a week is all you need to keep fit!

In news that will hearten the souls of all those couch potatoes out there, new research has shown that keeping fit and healthy may only require minutes of physical exercise each week.

7 Jun 2005

New series of human drug targets available to all researchers

The Structural Genomics Consortium (SGC), an Anglo-Canadian charitable consortium of public and private agencies including Oxford University, announced recently that it has delivered its first 50 human and malaria protein structures into the public domain on budget and two months ahead of schedule.

6 Jun 2005

Helmholtz Institute develops a new path to more effective antibiotics

Resistance to antibiotics has increased alarmingly in recent years. For example, in France the resistance of pneumococci has risen to 58% due to high rates of antibiotic prescription. Medical experts are sounding the alarm. Pharmacologists are seeking new antibiotically effective substances.

6 Jun 2005

Researchers successfully image delivery and gene expression of DNA nanoparticles into lungs of CF mice

Researchers at the American Society of Gene Therapy Meeting in St. Louis announced that by using imaging technologies, they are able to successfully trace the delivery of DNA nanoparticles and the extent of gene transfer in the lungs of cystic fibrosis (CF) animals.

6 Jun 2005

Genetics may play a role in the effectiveness of chemotherapy drugs

Today, the most common childhood cancer is cured in about 80 percent of patients; only forty years ago, this number was closer to five percent. In efforts to further increase the survival rate, researchers from St. Jude Children's Research Hospital, the University of Tennessee, and the University of Chicago studied how an individual's genetics might play a role in the effectiveness of chemotherapy drugs.

3 Jun 2005

Research findings suggest new treatment strategies for patients with cystic fibrosis

Cells sent to fight infections in the lungs of cystic fibrosis patients actually enhance the development of permanent bacterial infections, according to researchers at National Jewish Medical and Research Center.

3 Jun 2005

Research explains why Shigella and E. coli are rapidly becoming resistant to fluoroquinolones

Scientists at the Albert Einstein College of Medicine have discovered a novel strategy by which the bacterium that causes tuberculosis may soon be able to resist the effects of antibiotics known as fluoroquinolones.

3 Jun 2005

New research shows that threatened drug treatments slow damage to the brain caused by dementia

New research suggests that currently available anti dementia drugs not only alleviate the symptoms, but also reduce the destructive processes that kill brain cells in Alzheimer’s disease.

2 Jun 2005

Novel strategy proves highly effective in killing drug-resistant multiple myeloma cells

A novel strategy devised by Dana-Farber Cancer Institute scientists has proved highly effective in killing drug-resistant multiple myeloma cells in the laboratory and could open a new form of attack on the deadly blood cancer, they report.

2 Jun 2005

Novel topical treatment of psoriasis

Cytochroma Inc. today announced results from a Phase Ia clinical study for CTA018, a novel vitamin D analog developed for the treatment of psoriasis.

2 Jun 2005

Study links TNF to androgen deficiency in rheumatoid arthritis patients and suggest a novel pathway in inflammation

A protein involved in multiple cell functions, tumor necrosis factor (TNF) is perhaps best known for provoking destructive inflammation. Recently, drugs blocking the action of TNF have shown promise in the early treatment of rheumatoid arthritis (RA).

2 Jun 2005

Lactose intolerance linked to ancestral environment

Got milk? Many people couldn't care less because they can't digest it. A new Cornell University study finds that it is primarily people whose ancestors came from places where dairy herds could be raised safely and economically, such as in Europe, who have developed the ability to digest milk.

1 Jun 2005

Genetic variation alters response to anti-clotting drug warfarin

Millions of people take the anticoagulant drug warfarin to prevent harmful clotting after a heart attack, stroke, or major surgery. But the proper dose of warfarin can vary greatly and can be hard to predict.

1 Jun 2005

Scientists develop a way to block the signals responsible for neuropathic pain

Remember how it felt the last time you burned your finger on a hot stove? Imagine what it's like to have that burning pain in your hands or feet all the time and know there's virtually nothing you can do about it.

1 Jun 2005

Short bouts of very intense exercise improved muscle health and performance comparable to several weeks of traditional endurance training

Just six minutes of intense exercise a week could be as effective as an hour of daily moderate activity suggests new findings from researchers at McMaster University.

1 Jun 2005

Enzyme News and Research

Link between hyperglycemia (high blood glucose), overexpression of PKC-beta 2 and kidney disease

Researchers use RNAi libraries to identify regulators of apoptosis and chemoresistance

New start-up to market test that predicts heart attack risk

Designed drug for combined hormone and chemotherapy treatment

Prototype drug shows promise in slowing replication of the virus responsible for SARS

6 minutes exercise a week is all you need to keep fit!

New series of human drug targets available to all researchers

Helmholtz Institute develops a new path to more effective antibiotics

Researchers successfully image delivery and gene expression of DNA nanoparticles into lungs of CF mice

Genetics may play a role in the effectiveness of chemotherapy drugs

Research findings suggest new treatment strategies for patients with cystic fibrosis

Research explains why Shigella and E. coli are rapidly becoming resistant to fluoroquinolones

New research shows that threatened drug treatments slow damage to the brain caused by dementia

Novel strategy proves highly effective in killing drug-resistant multiple myeloma cells

Novel topical treatment of psoriasis

Study links TNF to androgen deficiency in rheumatoid arthritis patients and suggest a novel pathway in inflammation

Lactose intolerance linked to ancestral environment

Genetic variation alters response to anti-clotting drug warfarin

Scientists develop a way to block the signals responsible for neuropathic pain

Short bouts of very intense exercise improved muscle health and performance comparable to several weeks of traditional endurance training

Biochemistry eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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