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New role for a key protein involved in muscle contraction

Overturning a scientific stereotype, researchers at the University of Illinois at Chicago have discovered a new role for a key protein involved in muscle contraction and shown it is present not just in the cytoplasm of cells but in the nucleus as well.

1 Nov 2004

Trojan horse technique offers potential new therapeutic approach to Alzheimer's disease

A potential new therapeutic approach to Alzheimer's disease protects brain cells in culture by drastically reducing the neurotoxic amyloid protein aggregates that are critical to the development of the disease.

29 Oct 2004

Marijuana-like compounds may aid Parkinson's disease, pain and obesity

No longer a pipe dream, new animal research now indicates that marijuana-like compounds can aid a bevy of debilitating conditions, ranging from brain disorders such as amyotrophic lateral sclerosis (ALS) and Parkinson's disease, to pain and obesity.

28 Oct 2004

New direction for spinal cord research

A piece of the puzzle of how nerves find their way across the midline of the brain and spinal cord in a developing embryo has been found by Medical College of Georgia researchers.

28 Oct 2004

Ruboxistaurin may reduce vision loss from diabetes-induced eye disease

Eli Lilly and Company's investigational compound ruboxistaurin may reduce vision loss from diabetes-induced eye disease, according to new analyses of previously reported data presented at the 2004 Joint Meeting of the American Academy of Ophthalmology and the European Society of Ophthalmology in New Orleans, La.

26 Oct 2004

Genetic double-agents unmasked

Babraham Institute and Cancer Research UK scientists have discovered that certain enzymes with a key activity in the immune system may be important in stem-cell development, but may also work against us by contributing to the occurrence of cancer.

26 Oct 2004

Scientists closer to understanding the potential effects of anti-cholesterol drugs on Alzheimer's disease

Scientists at Jefferson Medical College and the Farber Institute for Neurosciences at Thomas Jefferson University in Philadelphia have taken another step in understanding the potential effects of anti-cholesterol drugs on Alzheimer's disease.

25 Oct 2004

Evidence links cellular iron deficiency to restless legs syndrome

Iron-deficient cells in the brain are mixing up central nervous system signals to the legs and arms causing the irresistible urges to move and creepy-crawly sensations that characterize restless legs syndrome (RLS), a Penn State College of Medicine study reports.

25 Oct 2004

Drinking regular cuppas could help improve your memory

Results of laboratory tests by a team from the University of Newcastle upon Tyne found that green and black tea inhibit the activity of certain enzymes in the brain which are associated with memory.

25 Oct 2004

Fatbuster drug targets obesity

A new drug to combat obesity at a cellular level is in the sights of a University of Queensland scientist.

25 Oct 2004

Allopurinol, a common gout drug may also offer some protection against colorectal cancer

A commonly prescribed drug used to treat gout may also offer some protection against colorectal cancer, according to a new study from researchers at the University of Michigan and in Israel.

25 Oct 2004

Tabletop DNA test laboratory cuts disease diagnosis down to 30 minutes

British scientists have developed a tabletop DNA test laboratory that can cut the diagnosis of disease and infection from hours to 30 minutes. This new test laboratory will soon begin trials in UK hospitals.

24 Oct 2004

New evidence supports value of fruits and vegetables in reducing breast cancer risk

Fruits and vegetables are known to reduce the risk of some cancers. Their antioxidant properties have been found to inhibit the generation of reactive oxidant species (ROS) that can damage and change DNA and lead to cancer.

22 Oct 2004

Molecule that helps DNA replicate may make good target for cancer therapy

In order to divide, cells must first replicate their chromosomes. Cells use an array of proteins to accomplish the job, including a large enzyme complex that synthesizes new strands of DNA.

21 Oct 2004

Research findings will likely aid efforts to develop a vaccine for Leishmania major

Researchers at Washington University School of Medicine in St. Louis and the University of Pennsylvania have found an immune system cell can "remember" a parasite's attack and help the body mount a more effective defense against subsequent invasions by the same parasite.

21 Oct 2004

Possible link between elevated calcium levels in older neurons and aging-related disorders of the brain

Brain cells become increasingly unable to regulate calcium loads as they age, becoming more vulnerable to injury and premature death, according to new findings that Virginia Commonwealth University researchers will present at an international conference this month.

20 Oct 2004

Researchers are one step closer to understanding how high carbohydrate diets lead to obesity and diabetes

Researchers at UT Southwestern Medical Center at Dallas are one step closer to understanding how high carbohydrate diets lead to obesity and diabetes.

19 Oct 2004

Discovery might improve design, effectiveness of anti-cancer drugs

Working with an enzyme that degrades anti-cancer drugs in humans, University of North Carolina at Chapel Hill biochemists and colleagues have made a discovery that they believe eventually could help improve such drugs’ design and effectiveness.

18 Oct 2004

More efficient method to sequence the human genome

Researchers at Baylor College of Medicine have been tabbed to find a more efficient method to sequence the human genome.

18 Oct 2004

One in four deaths among women with heart failure can be attributed to kidney problems

About one in four deaths among women with heart failure can be attributed to kidney problems, and more deaths are linked to renal insufficiency than to any other single risk factor, according to a new study in the Oct. 19, 2004 issue of the Journal of the American College of Cardiology.

18 Oct 2004

Enzyme News and Research

New role for a key protein involved in muscle contraction

Trojan horse technique offers potential new therapeutic approach to Alzheimer's disease

Marijuana-like compounds may aid Parkinson's disease, pain and obesity

New direction for spinal cord research

Ruboxistaurin may reduce vision loss from diabetes-induced eye disease

Genetic double-agents unmasked

Scientists closer to understanding the potential effects of anti-cholesterol drugs on Alzheimer's disease

Evidence links cellular iron deficiency to restless legs syndrome

Drinking regular cuppas could help improve your memory

Fatbuster drug targets obesity

Allopurinol, a common gout drug may also offer some protection against colorectal cancer

Tabletop DNA test laboratory cuts disease diagnosis down to 30 minutes

New evidence supports value of fruits and vegetables in reducing breast cancer risk

Molecule that helps DNA replicate may make good target for cancer therapy

Research findings will likely aid efforts to develop a vaccine for Leishmania major

Possible link between elevated calcium levels in older neurons and aging-related disorders of the brain

Researchers are one step closer to understanding how high carbohydrate diets lead to obesity and diabetes

Discovery might improve design, effectiveness of anti-cancer drugs

More efficient method to sequence the human genome

One in four deaths among women with heart failure can be attributed to kidney problems

Biochemistry eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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