Epidemiology News and Research

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Decreased air pollution continues to increase life expectancy in USA

Significant reductions in air pollution over the past decade have improved life expectancy across various US counties, report researchers, although they stress that optimum air quality levels have not yet been reached.

12 Dec 2012

Report analyzes risk factors and infection control strategies taken to prevent spread of NDM1-Kp

As the prevalence of antibiotic-resistant infections continue to rise around the world, a hospital in Canada detected the presence of New Delhi Metallo---lactamase-1-Producing Klebsiella pneumoniae (NDM1-Kp), a multidrug resistant bacteria that is resistant to carbapenems, one of the last lines of antibiotics.

12 Dec 2012

AstraZeneca, Case Western Reserve initiate AZD5847 Phase 2a trial in TB

Case Western Reserve University School of Medicine and AstraZeneca, a global biopharmaceutical company, today announced the first patient enrolled in a Phase 2a trial to assess the effectiveness of AZD5847, a new test drug for patients with tuberculosis (TB), including patients with HIV co-infection.

12 Dec 2012

Contact precautions reduce number of visits by healthcare workers and outside visitors

The prevention and control of healthcare-associated infections (HAIs) can help reduce patient morbidity and mortality, but a common prevention effort for patients with hard to treat infections known as contact precautions, can have positive and negative impacts on patient care.

12 Dec 2012

Study finds important links between Pf malaria and endemic Burkitt Lymphoma

New research, presented this morning at the 54th Annual Meeting of the American Society of Hematology (ASH), has identified important associations between Plasmodium falciparum (Pf) malaria and endemic Burkitt Lymphoma (eBL) that may help researchers identify young children who are more susceptible to eBL.

12 Dec 2012

Traumatic brain injury incidence: an interview with Professor Valery Feigin

Traumatic brain injury can be defined as an injury to the brain due to mechanical forces. Mechanical forces usually include falls, car accidents, accidental forces from another person or animal. It also includes sports-related brain injuries.

11 Dec 2012

Combination of ibrutinib and rituximab shows promise against chronic lymphocytic leukemia

A two-prong approach combining ibrutinib and rituximab (Rituxin) to treat aggressive chronic lymphocytic leukemia (CLL) produced profound responses with minor side effects in a Phase 2 clinical trial at the University of Texas MD Anderson Cancer Center.

11 Dec 2012

Preliminary results from Boehringer Ingelheim’s volasertib Phase II study on AML

Boehringer Ingelheim Pharmaceuticals, Inc. today reported preliminary results from the randomized Phase II part of a Phase I/II study involving the company's investigational compound volasertib in newly diagnosed patients with acute myeloid leukemia (AML) considered ineligible for intensive remission induction therapy.

11 Dec 2012

Boehringer Ingelheim to commence volasertib plus LDAC Phase III study for AML

New positive Phase II results from an interim analysis of the randomised Phase I/II study involving the company's investigational haematology/oncology compound volasertib in newly diagnosed patients with acute myeloid leukemia (AML) considered ineligible for intensive remission induction therapy were presented at the 54th American Society of Hematology (ASH) annual meeting in Atlanta, USA.

10 Dec 2012

Strong inverse association between caffeinated coffee intake and oral/pharyngeal cancer mortality

A new American Cancer Society study finds a strong inverse association between caffeinated coffee intake and oral/pharyngeal cancer mortality. The authors say people who drank more than four cups of caffeinated coffee per day were at about half the risk of death of these often fatal cancers compared to those who only occasionally or who never drank coffee.

10 Dec 2012

Study examines association between ischemic-hypoxic conditions and ADHD

Children who had in-utero exposure to ischemic-hypoxic conditions, situations during which the brain is deprived of oxygen, were significantly more likely to develop attention deficit hyperactivity disorder later in life as compared to unexposed children, according to a Kaiser Permanente study published in the journal Pediatrics.

10 Dec 2012

Exposure to passive smoking may increase risk of invasive meningococcal disease in children

The dangers of second-hand smoke (passive smoking) on children continue to become ever more apparent. A new study published in BioMed Central's open access journal BMC Public Health shows that second hand smoke and foetal exposure due to maternal smoking while pregnant significantly increase the risk of invasive meningococcal disease.

10 Dec 2012

Study identifies epigenetic events critical to cancer cell survival

USC Norris Comprehensive Cancer Center research that identifies specific genes that have to be turned off in order for cancer cells to survive was named one of the top major advances in cancer research this year by the American Society of Clinical Oncology (ASCO).

7 Dec 2012

Kidney cancer survival rates: an interview with Dr Wong-Ho Chow

There are two major forms of kidney cancer. One is called renal cell cancer, which is an adenocarcinoma that occurs in the renal parenchyma. The other major type is called renal pelvis cancer, which is mostly of transitional cell type and they form in the centre of the kidney where the urine collects.

7 Dec 2012

University of Michigan to create National Kidney Disease Registry

The University of Michigan Kidney Epidemiology and Cost Center will create a National Kidney Disease Registry to monitor kidney disease among America's veterans.

7 Dec 2012

Microarray technology provides comprehensive result during prenatal care of women

A new method for detecting abnormalities in unborn children is providing physicians with more information to analyze the results than conventional, microscopic testing, according to two George Washington University researchers.

7 Dec 2012

Johns Hopkins focuses on MRSA, motherhood in November-December 2012 research news brief

Johns Hopkins Nursing researchers focus on MRSA, motherhood, hospital stress, intimate partner violence, and more in the November-December 2012 research news brief.

6 Dec 2012

African American women less likely to receive axillary SLN biopsy for breast cancer

African American women with early stage, invasive breast cancer were 12 percent less likely than Caucasian women with the same diagnosis to receive a minimally invasive technique, axillary sentinel lymph node (SLN) biopsy, years after the procedure had become the standard of surgical practice, according to research from The University of Texas MD Anderson Cancer Center.

6 Dec 2012

Case Western Reserve to receive funding through Healthy Growth grant program

Case Western Reserve University School of Medicine announced that it will receive funding through the Achieving Healthy Growth program within the Grand Challenges in Global Health initiative.

6 Dec 2012

Prescribing opioids lead to admissions for substance abuse treatment and deaths

A Viewpoint article published recently in the Journal of the American Medical Association suggests that the clinical practice of prescribing amphetamines, opioids, and benzodiazepines to treat chronic pain may be contributing to the increase in fatal drug overdoses and the likelihood that those drugs will be diverted to the illegal market.

6 Dec 2012

Epidemiology News and Research

Decreased air pollution continues to increase life expectancy in USA

Report analyzes risk factors and infection control strategies taken to prevent spread of NDM1-Kp

AstraZeneca, Case Western Reserve initiate AZD5847 Phase 2a trial in TB

Contact precautions reduce number of visits by healthcare workers and outside visitors

Study finds important links between Pf malaria and endemic Burkitt Lymphoma

Traumatic brain injury incidence: an interview with Professor Valery Feigin

Combination of ibrutinib and rituximab shows promise against chronic lymphocytic leukemia

Preliminary results from Boehringer Ingelheim’s volasertib Phase II study on AML

Boehringer Ingelheim to commence volasertib plus LDAC Phase III study for AML

Strong inverse association between caffeinated coffee intake and oral/pharyngeal cancer mortality

Study examines association between ischemic-hypoxic conditions and ADHD

Exposure to passive smoking may increase risk of invasive meningococcal disease in children

Study identifies epigenetic events critical to cancer cell survival

Kidney cancer survival rates: an interview with Dr Wong-Ho Chow

University of Michigan to create National Kidney Disease Registry

Microarray technology provides comprehensive result during prenatal care of women

Johns Hopkins focuses on MRSA, motherhood in November-December 2012 research news brief

African American women less likely to receive axillary SLN biopsy for breast cancer

Case Western Reserve to receive funding through Healthy Growth grant program

Prescribing opioids lead to admissions for substance abuse treatment and deaths

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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