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Thousands got Exactech knee or hip replacements. Then, patients say, the parts began to fail.

Ron Irby expected the artificial knee implanted in his right leg in September 2018 would last two decades — perhaps longer.

10 Oct 2023

Owlstone Medical recruits first patient in phase 2 clinical trial for the early detection of lung cancer through breath biopsy

Owlstone Medical, the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced recruitment of the first patient into its EVOLUTION Phase 2 clinical trial following successful achievement of key safety and proof of concept milestones in Phase 1.

From Owlstone Medical Ltd 10 Oct 2023

Halting pandemics at the source: The call for a proactive 'One Health' approach

The recent PLoS Pathogens review emphasizes proactively preventing pathogen spillover from animals to humans as a strategy against future pandemics, advocating for a holistic One Health approach that considers the interconnectedness of humans, animals, and the environment. The study underscores the importance of primary prevention, differentiating it from secondary containment, and highlights the economic and societal benefits of preemptive actions over reactive responses.

10 Oct 2023

Antigenic cartography decodes the mysteries of SARS-CoV-2 variants and vaccines

Using antigenic cartography, researchers analyzed cross-reactivity patterns of SARS-CoV-2 variants and the effect of spike-protein changes on post-infection and vaccination immune responses. The study illuminated unique neutralization profiles and underscored the evolving defense mechanisms with repeated immunizations.

8 Oct 2023

Protein recombinant vaccine NVX-CoV2373 confers protection during Omicron dominant period in Italy

The NVX-CoV2373 COVID-19 vaccine offers significant protection against symptomatic infections, but its effectiveness against SARS-CoV-2 declines within four months, according to a study in JAMA Network Open using Italian data. However, its protection against symptomatic COVID-19 seems to remain stable during this period.

8 Oct 2023

Pyrvinium can be repurposed as a preventative treatment for stomach cancer

A study published Oct. 4 in Gastroenterology further validates that pyrvinium, a drug that has been used for decades for intestinal pinworms, can be repurposed as a preventative treatment for stomach cancer.

6 Oct 2023

Differences in immune responses to SARS-CoV-2 variants could inform future vaccine design

A person's immune response to variants of SARS-CoV-2, the virus that causes COVID-19, depends on their previous exposure - and differences in the focus of immune responses will help scientists understand how to optimize vaccines in the future to provide broad protection.

6 Oct 2023

Study reveals unexpected variation in genetic code of protist

Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics.

6 Oct 2023

Second international consensus report outlines gaps and opportunities for clinical translation of precision diabetes medicine

Precision medicine is part of the logical evolution of contemporary evidence-based medicine that seeks to reduce errors and optimize outcomes when making medical decisions and health recommendations.

4 Oct 2023

New artemisinin-resistant malaria parasite detected in Eritrea

Diagnosis of Plasmodium falciparum malaria using rapid diagnostic tests and treatment with artemisinin derivatives, the main component of the malaria treatments recommended by the World Health Organization (WHO), are under threat in the Horn of Africa.

29 Sep 2023

Parkinson's disease-related neuronal death more likely to occur at night

Disturbances in sleep patterns and the internal biological clock are frequently associated with Parkinson's disease.

29 Sep 2023

Researchers unlock new insights into hard-to-treat neuroendocrine tumors

Researchers at Boston Medical Center and Dana-Farber Cancer Institute conducted one of the first-ever analyses of neuroendocrine tumors (NETs) at single cell resolution, unlocking new insights into this rare and often hard-to-treat cancer.

28 Sep 2023

Evolution of new technologies to better diagnose bone fragility

Dual energy x-ray absorptiometry (DXA) is the gold standard for assessing bone mass and evaluating fracture risk.

27 Sep 2023

HMS researcher to lead $104 million effort to study bacteria and antibiotic resistance

Harvard Medical School researcher Johan Paulsson will lead a multi-institutional $104 million effort to study bacteria and antibiotic resistance, the U.S. Department of Health and Human Services announced today.

27 Sep 2023

Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses

Researchers used an interdisciplinary approach incorporating phylogenetics, 3D protein modeling, and plasmid design to identify and computationally design an antigen representing the core of most currently known sarbecoviruses.

27 Sep 2023

Medication and mutations: molnupiravir's impact on SARS-CoV-2 genomes

Researchers discovered molnupiravir-associated mutational signatures in SARS-CoV-2 genomes.

27 Sep 2023

Zeus Launches Next-Generation Tubing for Bioresorbable Vascular Scaffolds

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From Zeus Inc. 27 Sep 2023

Unions between close relatives may increase the risk of common diseases, study finds

A new study finds that consanguinity – unions between close relatives - may increase the risk of common diseases such as type 2 diabetes and post-traumatic stress disorder (PTSD).

26 Sep 2023

Study finds link between deforestation, mosquito biodiversity, and virus prevalence

How are environmental changes, loss of biodiversity, and the spread of pathogens connected? The answer is a puzzle. Scientists from Charité – Universitätsmedizin Berlin in cooperation with the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW) have now described one piece of that puzzle in the journal "eLife", showing that the destruction of tropical rainforests harms the diversity of mosquito species.

26 Sep 2023

Research uncovers a link between antiviral drug for COVID-19 and SARS-CoV-2 mutations

Researchers at the Francis Crick Institute, the University of Cambridge, Imperial College London, the University of Liverpool, the University of Cape Town and UKHSA have uncovered a link between an antiviral drug for COVID-19 infections called molnupiravir and a pattern of mutations in the SARS-CoV-2 virus.

25 Sep 2023

Evolution News and Research

Thousands got Exactech knee or hip replacements. Then, patients say, the parts began to fail.

Owlstone Medical recruits first patient in phase 2 clinical trial for the early detection of lung cancer through breath biopsy

Halting pandemics at the source: The call for a proactive 'One Health' approach

Antigenic cartography decodes the mysteries of SARS-CoV-2 variants and vaccines

Protein recombinant vaccine NVX-CoV2373 confers protection during Omicron dominant period in Italy

Pyrvinium can be repurposed as a preventative treatment for stomach cancer

Differences in immune responses to SARS-CoV-2 variants could inform future vaccine design

Study reveals unexpected variation in genetic code of protist

Second international consensus report outlines gaps and opportunities for clinical translation of precision diabetes medicine

New artemisinin-resistant malaria parasite detected in Eritrea

Parkinson's disease-related neuronal death more likely to occur at night

Researchers unlock new insights into hard-to-treat neuroendocrine tumors

Evolution of new technologies to better diagnose bone fragility

HMS researcher to lead $104 million effort to study bacteria and antibiotic resistance

Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses

Medication and mutations: molnupiravir's impact on SARS-CoV-2 genomes

Zeus Launches Next-Generation Tubing for Bioresorbable Vascular Scaffolds

Unions between close relatives may increase the risk of common diseases, study finds

Study finds link between deforestation, mosquito biodiversity, and virus prevalence

Research uncovers a link between antiviral drug for COVID-19 and SARS-CoV-2 mutations

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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