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Scientists use DNA sequencing to identify 'driver' mutations in cancer

Scientists at Washington University School of Medicine in St. Louis are using powerful DNA sequencing technology not only to identify mutations at the root of a patient's tumor - considered key to personalizing cancer treatment - but to map the genetic evolution of disease and monitor response to treatment.

2 Apr 2012

$Pazopanib demonstrates clinically meaningful activity in patients with refractory urothelial cancer$

Pazopanib demonstrates clinically meaningful activity in patients with refractory urothelial cancer

The antiangiogenic drug pazopanib has demonstrated clinically meaningful activity in patients with refractory urothelial cancer, according to results presented at the AACR Annual Meeting 2012, held here March 31 - April 4. The results also revealed that increases in interleukin-8 levels early after treatment with pazopanib may predict a lack of tumor response to the therapy.

2 Apr 2012

Scientists produce first genetic brain atlas

The first atlas of the surface of the human brain based upon genetic information has been produced by a national team of scientists, led by researchers at the University of California, San Diego School of Medicine and the VA San Diego Healthcare System.

30 Mar 2012

ProImmune introduces Special Assay Service

ProImmune Ltd., a leader in services for understanding immune responses, has launched a new Special Assay Service, providing unique, bespoke immunological assays, based on ProImmune's broad ranging proprietary platform technologies, to meet customers' assay needs.

29 Mar 2012

Researchers use game theory to understand dynamics of cancer tumor evolution under stress

In search of a different perspective on the physics of cancer, Princeton University and University of California, San Francisco researchers teamed up to use game theory to look for simplicity within the complexity of the dynamics of cooperator and cheater cells under metabolic stress conditions and high spatial heterogeneity. In the context of cancer, cooperator cells obey the general rules of communal survival, while cheater cells do not.

28 Mar 2012

ACS symposium focuses on biomimetics

Combining the secrets that enable water striders to walk on water and give wood its lightness and great strength has yielded an amazing new material so buoyant that, in everyday terms, a boat made from 1 pound of the substance could carry five kitchen refrigerators, about 1,000 pounds.

27 Mar 2012

The 13th EMBL/EMBO Science and Society conference

Why is the living world so diverse; that is, what forces and processes led to the evolution and proliferation of so many species? The dynamics that allow interacting species to coexist in an ecosystem simultaneously influence the productivity, nutrient dynamics and stability of that ecosystem.

23 Mar 2012

FDA clears multiple enhancements to St. Jude Medical's FFR measurement guidewire

St. Jude Medical, Inc., a global medical device company, today announced it has received U.S. Food and Drug Administration (FDA) clearance for multiple enhancements to its PressureWire Fractional Flow Reserve (FFR) measurement guidewire.

23 Mar 2012

Advances in Neuroimmune Biology explores maternal-fetal interactions

Fertility problems, recurrent miscarriages, and pregnancy complications can occur when maternal immunological tolerance of the fetus is impaired. G-rard Chaouat and colleagues from Inserm et Assistance Publique et Universit- Paris Sud Orsay, Hopital Antoine B-cl-re, Clamart Cedex, France, trace the evolution of the science of reproductive immunology to show how the current understanding of maternal-fetal tolerance/dialogue has developed, and its implications for the treatment of infertility disorders

22 Mar 2012

WESTMED collaborates with UnitedHealthcare to launch ACO

WESTMED Medical Group announced it is collaborating with the UnitedHealthcare and Optum businesses of UnitedHealth Group to launch an accountable care organization (ACO) for its more than 220 physicians in Westchester County, N.Y.

21 Mar 2012

New perspective on why the immune system makes us worse while trying to make us well

A new article in The Quarterly Review of Biology helps explain why the immune system often makes us worse while trying to make us well.

21 Mar 2012

RaySearch receives PMH contract for new adaptive radiation therapy solution

RaySearch Laboratories AB has been awarded a contract for a new adaptive radiation therapy solution at Princess Margaret Hospital (PMH) in Toronto, Canada. This means that RaySearch will deliver its treatment planning system RayStation to PMH where it will be used as the primary treatment planning tool for adaptive radiation therapy.

20 Mar 2012

Tyler Prize for Environmental Achievement honors two experts on air pollution

Tyler Prize for Environmental Achievement honors two experts on air pollution with the 2012 Tyler Prize for their work to advance the scientific understanding of air pollution, and develop solutions to reduce the danger to human health and the impact on climate change.

20 Mar 2012

Tobii completes USD $21 million funding round

Tobii Technology, the global leader in eye tracking and gaze interaction, announced today that it has closed a USD $21M funding round. New investor Intel Capital joins existing investors Amadeus Capital, Investor Growth Capital and Northzone Ventures.

20 Mar 2012

Study identifies new hypervariable regions in human gut viruses

A growing body of evidence underscores the importance of human gut bacteria in modulating human health, metabolism, and disease. Yet bacteria are only part of the story. Viruses that infect those bacteria also shape who we are. Frederic D. Bushman, PhD, professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania, led a study published this month in the Proceedings of the National Academy of Sciences that sequenced the DNA of viruses -- the virome -- present in the gut of healthy people.

20 Mar 2012

Medicare plan will be central to Ryan GOP budget

House Budget Committee Chairman Paul Ryan, R-Wis., is set to unveil a new budget plan on Tuesday. Both Democrats and Republicans are poised to revive the pitched debate over controversial proposals related to the Medicare programs.

19 Mar 2012

First Edition: March 19, 2012

Today's headlines reflect the anticipation and anxiety that surrounds the Supreme Court's upcoming health law oral arguments.

19 Mar 2012

arGEN-X introduces NHance technology to create therapeutic antibodies

arGEN-X announces today the launch of NHance, its latest cutting-edge technology enabling the creation of truly differentiated human antibody therapeutics.

19 Mar 2012

Study reveals why development of HIV treatments has been difficult

A new research report appearing in the March 2012 issue of the journal Genetics shows why the development of a cure and new treatments for HIV has been so difficult. In the report, an Australian scientist explains how he used computer simulations to discover that a population starting from a single human immunodeficiency virus can evolve fast enough to escape immune defenses.

16 Mar 2012

Epigenetic designer baby may prove to be a non-starter

Epigenetics is the new hip science. Time Magazine's front cover and article, 'Why your DNA isn't your Destiny' from January 2010 explains why. Its more explicit subtitle provided the hook - 'The new science of epigenetics reveals how the choices you make can change your genes - and those of your kids'. Who wouldn't be interested in this?

16 Mar 2012