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GSK receives FDA approval for combination of Mekinist with Tafinlar for treatment of melanoma

GlaxoSmithKline plc announced today that the U.S. Food and Drug Administration (FDA) has approved Mekinist® (trametinib) for use in combination with Tafinlar® (dabrafenib) for the treatment of patients with unresectable melanoma (melanoma that cannot be removed by surgery) or metastatic melanoma (melanoma which has spread to other parts of the body) with BRAF V600E or V600K mutations.

9 Jan 2014

Norwegian researchers map genetic variations associated with increased risk of MS and MG

The Norwegian researchers have taken part in an international cooperative effort to map 110 genetic variations that increase the risk of MS and MG. Most of these genetic variations have been mapped in recent years.

9 Jan 2014

Mild electronic stimulation therapy to upper airway during sleep effective in reducing OSA

Results published in a new study in the Jan. 9 issue of the New England Journal of Medicine report that mild electronic stimulation therapy to the upper airway during sleep is effective in reducing obstructive sleep apnea (OSA).

9 Jan 2014

Implantation of sleep apnea device can lead to improvements for patients with OSA

Implantation of a sleep apnea device called Inspire- Upper Airway Stimulation therapy can lead to significant improvements for patients with obstructive sleep apnea, according to a study published today in the New England Journal of Medicine.

9 Jan 2014

Research opens door to new direction of PAH treatment

The development of new, more effective vasodilators to treat pulmonary arterial hypertension has been hampered because of their systemic toxicity and adverse side effects. An international team of investigators seeking to surmount these problems and increase drug efficacy have determined that a vascular homing peptide can selectively target hypertensive pulmonary arteries to boost the pulmonary but not systemic effects of vasodilators. Importantly for potential clinical use, this peptide retains its activity when given sublingually. The results using a rat model of PAH are published in the American Journal of Pathology.

8 Jan 2014

EC grants approval for ABRAXANE in combination with gemcitabine for metastatic pancreatic cancer

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation, today announced that the European Commission has granted approval for ABRAXANE (paclitaxel formulated as albumin bound nanoparticles, or nab-paclitaxel) in combination with gemcitabine for first-line treatment of adult patients with metastatic adenocarcinoma of the pancreas, or metastatic pancreatic cancer.

7 Jan 2014

Food labeling, product placement intervention can promote healthy choices

The use of color-coded "traffic light" food labels and changes in the way popular items are displayed appear to have produced a long-term increase in the choice of more healthful food items among customers in a large hospital cafeteria. A Massachusetts General Hospital team reports in the American Journal of Preventive Medicine that the previously reported changes in the proportions of more and less healthy foods purchased in the months after their program began have persisted up to two years after the labeling intervention was introduced.

7 Jan 2014

Study shows link between nurse fatigue and clinical decision regret

Fatigued nurses are more likely to express concern that they made a wrong decision about a patient's care, according to a study in the January issue of American Journal of Critical Care (AJCC).

3 Jan 2014

Who do Americans want care from? Doctors or other practitioners?

Doctors who provide personalized care get organized into a new group while a new survey seems to suggest American prefer getting their care from a doctor instead of nurse practitioners or physician assistants.

24 Dec 2013

Solana's CrossCHECK Plating System receives FDA clearance

Solana Surgical, LLC, a growth extremity company, announces the FDA Clearance of the CrossCHECK™ Plating System, a new implant system for orthopedic and podiatric surgeons' use in foot and ankle procedures. Commercialization will follow in the first quarter of 2014.

20 Dec 2013

Five tips to identify individuals who may be vulnerable during holidays

While it is true that suicide rates are actually lower at the holidays compared to other times of the year, the holidays can be a very lonely time for those with nowhere to go and no one to turn to.

20 Dec 2013

Copenhagen scientists study link between congenital arrhythmia and hypoglycemia

In a new study, scientists from University of Copenhagen document a connection between congenital arrhythmia and the bodies' ability to handle sugar. The results can be of vital importance for patients with the disease and for the future treatment of diabetes. The new study has just been published in the scientific journal Diabetes.

19 Dec 2013

New study aims to identify breast cancer patients most susceptible to post-treatment fatigue

Although the prevalence and impact of cancer-related fatigue has been well established, very little is known about its predictors, mechanisms for development, and persistence post-treatment. A new research study at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, in partnership with UCLA, is aimed at identifying breast cancer patients most susceptible to post-treatment fatigue by measuring biological, behavioral and social risk factors.

19 Dec 2013

Study identifies atrial fibrillation as a growing and serious global health problem

Atrial fibrillation, long considered the most common condition leading to an irregular heartbeat, is a growing and serious global health problem, according to the first study ever to estimate the condition's worldwide prevalence, death rates and societal costs.

18 Dec 2013

Toddlers’ bedtime resistance may contribute to sleep problems

The bedtime you select for your toddler may be out of sync with his or her internal body clock, which can contribute to difficulties for youngsters attempting to settle in for the night, according to a new University of Colorado Boulder study.

17 Dec 2013

Taking simple steps to stay healthy while traveling can make holidays more enjoyable, says expert

Traveling long distances during the holidays -- whether by car, plane or train -- is a common custom for many Americans, but taking health precautions for the journey isn't often at the top of to-do lists. Taking some simple steps to stay healthy while traveling can make the holidays more enjoyable and safe, according to a Mayo Clinic expert.

17 Dec 2013

Erlotinib ‘dose-to-rash’ strategy effective in advanced NSCLC

Erlotinib as first-line therapy in patients with advanced non-small-cell lung cancer is equivalent to chemotherapy with regard to overall survival, an “all-comers” phase II trial has shown.

16 Dec 2013

Cetuximab fails in second-line combination for recurrent NSCLC

Results from a phase III trial indicate that cetuximab should not be given alongside chemotherapy in patients with recurrent non-small-cell lung cancer after platinum-based therapy.

13 Dec 2013

Methodology needed to diagnose quality of life of individual cancer patients or survivors

Due to improved treatments and technologies, more children than ever are surviving cancer. Unfortunately, about 70 percent of these children experience late effects from their disease and treatment 30 years after their cancer diagnosis, which University of Florida Health researchers say significantly impact their quality of life.

13 Dec 2013

Researchers develop first test to identify acute mountain sickness

The first test to identify acute mountain sickness has been developed by a team of researchers in Italy and France and is presented today at EuroEcho-Imaging 2013. The test could revolutionise trekking and climbing by predicting who will develop the potentially deadly condition so they can avoid high altitudes, ascend more gradually or take preventative medication.

12 Dec 2013

Fatigue News and Research

GSK receives FDA approval for combination of Mekinist with Tafinlar for treatment of melanoma

Norwegian researchers map genetic variations associated with increased risk of MS and MG

Mild electronic stimulation therapy to upper airway during sleep effective in reducing OSA

Implantation of sleep apnea device can lead to improvements for patients with OSA

Research opens door to new direction of PAH treatment

EC grants approval for ABRAXANE in combination with gemcitabine for metastatic pancreatic cancer

Food labeling, product placement intervention can promote healthy choices

Study shows link between nurse fatigue and clinical decision regret

Who do Americans want care from? Doctors or other practitioners?

Solana's CrossCHECK Plating System receives FDA clearance

Five tips to identify individuals who may be vulnerable during holidays

Copenhagen scientists study link between congenital arrhythmia and hypoglycemia

New study aims to identify breast cancer patients most susceptible to post-treatment fatigue

Study identifies atrial fibrillation as a growing and serious global health problem

Toddlers’ bedtime resistance may contribute to sleep problems

Taking simple steps to stay healthy while traveling can make holidays more enjoyable, says expert

Erlotinib ‘dose-to-rash’ strategy effective in advanced NSCLC

Cetuximab fails in second-line combination for recurrent NSCLC

Methodology needed to diagnose quality of life of individual cancer patients or survivors

Researchers develop first test to identify acute mountain sickness

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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