Fentanyl News and Research

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Fentanyl is a powerful synthetic opiate analgesic similar to but more potent than morphine. It is typically used to treat patients with severe pain, or to manage pain after surgery. It is also sometimes used to treat people with chronic pain who are physically tolerant to opiates. It is a schedule II prescription drug.

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

As the COVID-19 pandemic nears the two-year mark, Northwestern Medicine scientists continue to tackle every facet of the disease, from investigating coronavirus vaccines' potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago.

30 Nov 2021

CDC launches complementary education campaigns to save more lives from drug overdose

To save more lives from drug overdose, the Centers of Disease Control and Prevention (CDC) recently launched four complementary education campaigns intended to reach young adults ages 18-;34 years.

30 Oct 2021

Study highlights major role of polysubstance use in drug overdose risk

Even as the opioid epidemic dominated national attention over the past decade, the rate of overdose deaths involving cocaine, methamphetamine and other stimulants tripled, a new study in veterans suggests.

21 Oct 2021

Women may be more vulnerable to drug addiction and addiction-like behaviors than men

The results of several new studies focusing on sex differences in pain and addiction indicate females could be more susceptible to drug addiction and addiction-like behaviors than males. Researchers also explored the role of lack of sleep on the likeliness to relapse. This is due in part to hormone differences in females and males. Data from the studies will be presented virtually October 19–22 at the American Physiological Society's seventh conference on New Trends in Sex and Gender Medicine.

20 Oct 2021

Researchers explore how opioids may have become so widely abused

Researchers may have uncovered new answers on how to create safer opioids. Design a new opioid to bypass the part of brain that feels pleasure, but retain the analgesic properties, which make opioids one of the most effective pain relievers.

15 Oct 2021

Study identifies hotspots for opioid overdose and other drug-related disorders

Combining emergency medical services and vital statistics data, a new study led by researchers from Tufts University School of Medicine provides a unique view of the opioid overdose epidemic in an urban area.

12 Oct 2021

Needle exchanges are targeted by eco-rooted lawsuits. A new California law will stop that.

For more than 30 years, public health officials and nonprofits in California have provided clean hypodermic needles to people who use them to inject drugs.

6 Oct 2021

Study finds rise in methamphetamine-involved overdose deaths from 2015 to 2019

Overdose deaths involving methamphetamine nearly tripled from 2015 to 2019 among people ages 18-64 in the United States, according to a study by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health.

22 Sep 2021

Study finds increasing disparities in opioid overdose deaths for Black people

Non-Hispanic Black individuals in four U.S. states experienced a 38% increase in the rate of opioid overdose deaths from 2018 to 2019, while the rates for other race and ethnicity groups held steady or decreased, according to a new study by the National Institutes of Health published in the American Journal of Public Health.

9 Sep 2021

Mobile telemedicine unit found to be effective in treating opioid use disorder in rural areas

Rural regions in the U.S. have been disproportionately affected by the opioid epidemic, while also having the fewest number of programs to treat opioid use disorder.

28 Aug 2021

Researchers use residues in wastewater to study illicit drug consumption

At the start of the COVID-19 pandemic, stay-at-home orders and other restrictions drastically affected how people lived and worked, resulting in social isolation and economic instability. Now, researchers show that some people turned to a variety of drugs for relief. Using wastewater analysis, the team identified a spike in consumption of easily abused prescription opioids and anti-anxiety sedatives, while some illicit drug use plummeted, between March and June 2020.

23 Aug 2021

Contingency management at end-of-treatment helps to overcome opioid use disorder

The opioid epidemic remains a U.S. public health crisis and has only worsened since the COVID-19 pandemic began in 2020, with opioid deaths accounting for 69,000 of 93,000 overdose-related deaths in 2020, according to provisional drug overdose data released by the U.S. Centers for Disease Control and Prevention in July 2021.

5 Aug 2021

As holdout Missouri joins nation in monitoring opioid prescriptions, experts worry

Kathi Arbini said she felt elated when Missouri finally caught up to the other 49 states and approved a statewide prescription drug monitoring program this June in an attempt to curb opioid addiction.

26 Jul 2021

New open-source tool designed to predict drug overdose mortality in the U.S.

For two decades, the number of Americans who die each year from drug overdoses has steadily risen, from less than 20,000 in 1999 to more than 80,000 in 2020.

10 Jun 2021

Clinical trial investigates effectiveness of delivering HIV, substance use care through mobile clinics

A clinical trial is underway in five U.S. cities to determine whether delivering integrated health services through mobile clinics can improve HIV and substance use outcomes among people with opioid use disorder who inject drugs.

9 Jun 2021

Research opens alternative therapeutic avenues for treatment of chronic pain

Building on previous findings, scientists have demonstrated that conolidine interacts with the newly identified opioid receptor ACKR3/CXCR7.

3 Jun 2021

Opioids like ‘lean’ permeate hip-hop culture, but dangers are downplayed

Nykerrius Williams knows about the close relationship between hip-hop and opioid use. Williams, 27, an independent rapper from Gibsland, Louisiana, who goes by the name Young Nyke, took oxycodone pills for the first time when he was 16 and has continued patterns of misuse of those pills, as well as Lortabs, Xanax and codeine cough syrups, until recently. To him, it's part of the business.

28 May 2021

Blood sample analysis can help determine the origin of drugs

The opioid fentanyl is not only used in medical practice as a painkiller, but is also a popular recreational drug. In the United States in particular, fentanyl plays an important role in the opioid crisis that claims many victims every day.

27 May 2021

Pain monitoring technology can reduce intraoperative opioid consumption

A new study has shown that effective opioid-sparing anaesthesia with dexmedetomidine can be guided with NOL pain monitoring technology (Medasense, Israel). The study showed that the NOL monitor is able to detect the effect of dexmedetomidine on the patient's pain response and enable administration of less intraoperative opioids.

26 May 2021

Opioid prescribing behavior can also be decreased by supply shortage, shows study

When evaluating the opioid crisis, research reveals that external factors - such as the volume of pre-filled syringes, or a default number of opioid tablets that could easily be ordered at discharge for the patient - can shift prescribing and compel emergency department (ED) physicians to administer or prescribe greater quantities of opioids.

6 May 2021