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HIV status does not affect Tecovirimat treatment outcomes for Mpox virus infection

A retrospective cohort study comparing the clinical presentation and treatment outcomes of people with HIV and those without HIV who were treated with tecovirimat for confirmed mpox virus infection. The study found that HIV status did not seem to affect treatment outcomes.

4 May 2023

Genomic study helps develop mRNA vaccine candidate against dengue virus

Researchers in India say that data from a detailed genomic study of the dengue virus has helped them develop an mRNA (messenger RNA) vaccine candidate capable of neutralizing all four strains of the pathogen.

3 May 2023

Urgent call for improved diagnostics, treatments, and vaccines against deadly Hantavirus

Scientists discuss hantavirus infections, which are a type of viral hemorrhagic fever that can be transmitted to humans through exposure to infected rodents in endemic areas.

30 Apr 2023

Tracking SARS-CoV-2 Omicron variant XBB1.16

The World Health Organization recently named the SARS-CoV-2 Omicron variant XBB1.16 a variant of interest to encourage tracking of this genetic variant of the pandemic coronavirus.

28 Apr 2023

Advanced DNA sequencing technique reveals the reason for COVID-19 related sudden child mortality

Sudden, unexplained child mortality is a tragedy; determining the cause of death is important for improving healthcare and providing loved ones with closure.

27 Apr 2023

Colchicine therapy benefits pediatric long COVID patients suffering from recurring fever

Researchers at National Jewish Health found that a subset of children suffering recurring fevers as a result of long COVID-19, benefited from a daily medication treatment commonly used for gout and periodic fever syndrome.

25 Apr 2023

Did a military lab spill anthrax into public waterways? New book reveals details of a US leak

Unsterilized laboratory wastewater from the U.S. Army Medical Research Institute of Infectious Diseases at Fort Detrick, Maryland, spewed out the top of a rusty 50,000-gallon outdoor holding tank, the pressure catapulting it over the short concrete wall that was supposed to contain hazardous spills.

25 Apr 2023

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

CMPK2 identified as a potential pan-flavivirus inhibitor, restricting virus replication and providing a basis for developing new antiviral treatments.

23 Apr 2023

UT Southwestern expert says common skin problems could signal a more serious rheumatic disease

While rheumatic diseases typically affect the joints, muscles, or ligaments, the first signs of a problem may appear on the skin.

21 Apr 2023

Most kids recover from Lyme disease within six months of completing antibiotic treatment

A majority of parents of children diagnosed with Lyme disease reported that their kids recovered within six months of completing antibiotic treatment, according to a new joint study from Children's National Research Institute and the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, published in Pediatric Research.

21 Apr 2023

Research reveals how a bacterial pathogen creates syringe-like structures to infect the intestines

Researchers at UT Southwestern Medical Center have discovered how a bacterium that infects people after they eat raw or undercooked shellfish creates syringe-like structures to inject its toxins into intestinal cells.

20 Apr 2023

Central African Republic experiences severe health and humanitarian emergency, study reveals

A new study by public health researchers presents stark evidence that the Central African Republic (CAR) is experiencing a severe health and humanitarian emergency, with what is likely the highest measured nationwide mortality rate in the world, a rate four times higher than a 2010 United Nations estimate.

19 Apr 2023

Small vesicles released by intestinal bacteria induce immune activation and progression of liver cirrhosis

Researchers from Niigata University and Kyoto Prefectural University have revealed that small vesicles, around 100 nm in size, released by intestinal bacteria induce immune activation and progression of liver cirrhosis, as well as reduction of serum albumin level, subsequently leading to edema and ascites.

19 Apr 2023

Evolution of H3 avian influenza virus in China: Implications for pandemic preparedness

This paper analyzes the evolution of the H3 subtype of avian influenza virus in China from 2009 to 2022, including its spatial and temporal distribution and genetic changes. The findings have implications for pandemic preparedness.

18 Apr 2023

Tissue-resident memory cells are key to immunity to Salmonella in mice

Salmonella infections cause about a million deaths a year worldwide, and there is an urgent need for better vaccines for both typhoid fever and non-typhoidal Salmonella disease.

18 Apr 2023

Relaxation of pandemic measures resulted in the surge of Strep A infections to above pre-COVID levels

New research from France shows that infections cause by Group A Streptococcus (GAS) fell by 80% as the first COVID lockdown took effect in March 2020 and stayed at low levels until March 2022, from which point they increased by 18% a month to rise well above pre-COVID levels.

17 Apr 2023

Cellulose nanocrystals as a barrier against mosquito bites

Researchers examined the barrier effect of cellulose nanocrystals (CNCs) on mosquitoes.

13 Apr 2023

Genomic study reveals Babesia duncani's pathogenicity and virulence

'Tis the season for hiking now that spring has arrived and temperatures are on the upswing. But with hikes come insect bites and on the increase in North America is babesiosis, a malaria-like disease spread especially between May and October by a tick.