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NIAID launches clinical trials of dengue vaccine

After more than a decade of development, the National Institute of Allergy and Infectious Diseases (NIAID) has started clinical trials to test a vaccine to protect against the dengue virus, a product researchers hope may one day "help prevent a disease to which 2.5 billion people are exposed," CIDRAP News reports (Roos, 8/9).

11 Aug 2010

Surveillance systems find no major disease outbreaks since Haiti quake; Media examine aid disbursements

Haitian and U.S. public health experts recently reported that two new surveillance systems set up in Haiti after the January earthquake showed that no major disease outbreaks had developed and that the new systems could be part of the foundation of the country's health system in the long term, Reuters reports. The findings were published Friday in the CDC's Morbidity and Mortality Weekly Report.

10 Aug 2010

NIH begins human clinical testing for dengue virus vaccine

After more than a decade of development at the National Institutes of Health, a vaccine to prevent infection by the mosquito-borne dengue virus has begun human clinical testing. The vaccine was developed by scientists at the National Institute of Allergy and Infectious Diseases (NIAID) and is undergoing clinical study at the Johns Hopkins Bloomberg School of Public Health in Baltimore.

10 Aug 2010

First Salmonella lawsuit filed against Yum Brands

The first Salmonella lawsuit has been filed in the pair of Salmonella outbreaks that has sickened 155 people in 21 states. The lawsuit was filed against Yum! Brands (the parent company of Taco Bell) in the Commonwealth of Kentucky, Franklin County Circuit Court. The lawsuit was filed on behalf of a Scott county resident by food safety law firm Marler Clark.

7 Aug 2010

Department of Agriculture advises consumers to discard Jersey Hollow Farm's raw milk

The Department of Agriculture today advised consumers who purchased raw milk from Norman Z. and Edith B. Sauder, of Jersey Hollow Farm in Kutztown, Berks County, to discard the product immediately because of potential bacterial contamination.

7 Aug 2010

ViroPharma announces data on safety, efficacy of Cinryze to treat acute angioedema attacks

ViroPharma Incorporated today announced that data from Phase 3 studies of Cinryze (C1 esterase inhibitor [human]) have been published in the August 5, 2010 issue of the New England Journal of Medicine. The paper entitled Nanofiltered C1 Inhibitor Concentrate for Treatment of Hereditary Angioedema by Dr. Bruce L. Zuraw et al. describes the safety and efficacy of Cinryze in treating and preventing attacks of hereditary angioedema. Cinryze is the first and only FDA-approved C1 esterase inhibitor therapy indicated for routine prophylaxis against angioedema attacks in adolescent and adult patients with hereditary angioedema (HAE), a rare, debilitating and potentially fatal disease; it is not approved by the FDA to treat acute angioedema attacks.

6 Aug 2010

New research on use of medicine, diet to prevent UV-induced skin cancer

In most cases, non-melanoma skin cancers are caused by overexposure to ultraviolet radiation - the invisible rays from the sun that can burn the skin. To reduce the risk of skin cancer, dermatologists encourage the public to Be Sun Smart, including limiting sun exposure and using broad-spectrum sunscreens.

6 Aug 2010

Merck's two pivotal boceprevir Phase III registration studies for chronic HCV meet primary endpoint

Merck reported that two pivotal Phase III registration studies for boceprevir, its investigational oral hepatitis C protease inhibitor, have been completed and met the primary endpoints: in both studies in patients with chronic hepatitis C virus (HCV) genotype 1 infection, the addition of boceprevir to treatment with PEGINTRON® and REBETOL® significantly increased the number of patients who achieved sustained virologic response, compared to control groups that received Peg/riba plus placebo.

5 Aug 2010

Study explores role of genetic influence on ulcerative colitis

Adults diagnosed with ulcerative colitis after age 50 are more likely to achieve remission from their symptoms than patients diagnosed at younger ages, even when those patients receive similar treatments, according to research at Washington University School of Medicine in St. Louis.

3 Aug 2010

Pakistani officials fear cholera outbreak after massive flooding

After floods in northwest Pakistan have "already killed up to 1,200 people" and forced 2 million from their homes, authorities are now concerned about disease spread, the Associated Press reports.

2 Aug 2010

Phase I/II clinical study data of OncoVEXGM-CSF for head and neck cancer published in Clinical Cancer Research

BioVex Inc, a company developing new generation biologics for the treatment of cancer and prevention of infectious disease, announces that the data from its completed Phase I/II clinical study of OncoVEXGM-CSF for the first line treatment of head and neck cancer is being published today in Clinical Cancer Research, an ASCO publication.

2 Aug 2010

Researchers identify new genetic route to treat epilepsy

New research points to a genetic route to understanding and treating epilepsy. Timothy Jegla, an assistant professor of biology at Penn State University, has identified an ancient gene family that plays a role in regulating the excitability of nerves within the brain.

2 Aug 2010

Australian scientists uncover the secrets behind one of nature’s most extraordinary biological machines

Scientists from the Victor Chang Cardiac Research Institute (VCCRI), Sydney, have discovered the secrets behind the tiny motors in bacteria that allow them to swim rapidly towards nutrients and away from toxins, which is crucial to the spread of bacterial infection. These motors can rotate at up to 100,000 revolutions per minute, yet can switch directions in milliseconds.

1 Aug 2010

Painkiller combinations cost more but are less effective: Report

In a new article in the journal Australian Prescriber, there is a warning that combination painkillers cause more side effects and may not provide the relief promised. This comes from the National Prescribing Service (NPS), Australia's medicine review body.

1 Aug 2010

Stop & Shop Supermarket announces voluntary recall of Nature's Promise Alfalfa, Zesty Sprouts

The Stop & Shop Supermarket Company has announced a voluntary recall of Nature's Promise Alfalfa and Zesty Sprouts because they have the potential to be contaminated with listeria monocytogenes.

31 Jul 2010

FDA announces approval of vaccines for 2010-2011 US influenza season

The U.S. Food and Drug Administration announced today that it has approved vaccines for the 2010-2011 influenza season in the United States.

31 Jul 2010

VBDS secondary to nevirapine use in HIV-positive, pregnant female: Report

Vanishing bile duct syndrome refers to a group of disorders characterized by destruction and disappearance of intrahepatic (inside the liver) bile ducts. Multiple causes have been identified including infections, malignancies, autoimmune conditions and adverse effects of medications. The usual course of this condition is variable and many patients with VBDS respond to treatment of the underlying condition and/ or removal of the offending agent. However, others progress to cirrhosis and end stage liver disease requiring liver transplantation.

31 Jul 2010

Need for shelter in Haiti; Avoiding disease outbreaks; Presidential election

USAID Director Rajiv Shah "says shelter and rubble removal are immediate priorities in the reconstruction efforts in earthquake-devastated Haiti," VOA News reports. Shah briefed the House Foreign Relations Subcommittee on the Western Hemisphere Thursday, and also "said between 300,000 and 400,000 units of shelter are needed. He said aid workers are trying to provide about 135,000 transitional structures right now."

31 Jul 2010

Respiratory symptoms are accurate indicators of influenza infection

New research shows that individuals with mild H1N1 infection may go undetected using standard diagnostic criteria, according to a study in the August issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology, (APIC). The study concludes that coughing or other respiratory symptoms are more accurate in determining influenza infection than presence of a fever.

30 Jul 2010

Oxford Finance leads $30 million credit facility provided to Cadence for launch of OFIRMEV

Oxford Finance Corporation, a subsidiary of Sumitomo Corporation, today announced that it was the lead lender for a $30 million credit facility provided to Cadence Pharmaceuticals. Silicon Valley Bank and GE Financial Services, Inc. also participated in the loan agreement. This infusion of capital will support the company's potential launch of their investigational product candidate, OFIRMEV™, an intravenous formulation of acetaminophen that is currently marketed in Europe for the treatment of acute pain and fever.

29 Jul 2010

Fever News and Research

NIAID launches clinical trials of dengue vaccine

Surveillance systems find no major disease outbreaks since Haiti quake; Media examine aid disbursements

NIH begins human clinical testing for dengue virus vaccine

First Salmonella lawsuit filed against Yum Brands

Department of Agriculture advises consumers to discard Jersey Hollow Farm's raw milk

ViroPharma announces data on safety, efficacy of Cinryze to treat acute angioedema attacks

New research on use of medicine, diet to prevent UV-induced skin cancer

Merck's two pivotal boceprevir Phase III registration studies for chronic HCV meet primary endpoint

Study explores role of genetic influence on ulcerative colitis

Pakistani officials fear cholera outbreak after massive flooding

Phase I/II clinical study data of OncoVEXGM-CSF for head and neck cancer published in Clinical Cancer Research

Researchers identify new genetic route to treat epilepsy

Australian scientists uncover the secrets behind one of nature’s most extraordinary biological machines

Painkiller combinations cost more but are less effective: Report

Stop & Shop Supermarket announces voluntary recall of Nature's Promise Alfalfa, Zesty Sprouts

FDA announces approval of vaccines for 2010-2011 US influenza season

VBDS secondary to nevirapine use in HIV-positive, pregnant female: Report

Need for shelter in Haiti; Avoiding disease outbreaks; Presidential election

Respiratory symptoms are accurate indicators of influenza infection

Oxford Finance leads $30 million credit facility provided to Cadence for launch of OFIRMEV

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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