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MYCN amplification can serve as a favorable prognostic indicator for neuroblastoma

Neuroblastoma, a malignant tumor that primarily affects infants and young children, is a leading cause of death for children with cancer. When amplification of the MYCN oncogene is found in the tumor, it usually indicates an aggressive tumor with rapid progression of the disease and a poor outcome. Thus MYCN amplification has come to be used as a prognostic indicator.

12 Aug 2011

NPL scientists mimick the ways viruses infect human cells and deliver genetic material

Scientists at the National Physical Laboratory (NPL) have mimicked the ways viruses infect human cells and deliver their genetic material. The research hopes to apply the approach to gene therapy - a therapeutic strategy to correct defective genes such as those that cause cancer.

12 Aug 2011

New treatment uses lasers to stimulate stem cells and reduce heart scarring

After a heart attack or stroke, heart scarring can lead to dangerously paper-thin heart walls and a decreased ability to pump blood through the body. Although the heart is unable to completely heal itself, a new treatment developed at Tel Aviv University uses laser-treated bone marrow stem cells to help restore heart function and health.

11 Aug 2011

Novel link between two receptors mediates fungal recognition in macrophages

Whitehead Institute researchers have uncovered a novel association between two fungal recognition receptors on the surface of certain immune cells, called macrophages.

9 Aug 2011

Scientists identify small molecule inhibitors of cellular uptake

Scientists from Freie Universität Berlin and the NeuroCure Cluster of Excellence led by biochemist Volker Haucke in collaboration with colleagues from Australia and the Leibniz Institute for Molecular Pharmacology in Berlin have developed small molecules that inhibit the internalization of important signaling molecules but also of pathogenic organisms such as the immunodeficiency virus and bacteria into cells.

5 Aug 2011

Chromogenic in situ hybridization can identify ALK rearrangement in lung cancer patients

A relatively simple and inexpensive method may be used to determine whether a lung cancer patient is a candidate for crizotinib therapy, according to research published in the August issue of the Journal of Thoracic Oncology, the official monthly journal of the International Association for the Study of Lung Cancer.

3 Aug 2011

Pregnancy and electromagnetic fields linked to asthma in kids

According to American researchers, children whose mothers had high exposure to electromagnetic fields while pregnant may have an increased risk of developing asthma. Many prior studies have failed to consistently show that chronic exposure to electromagnetic fields - from power lines and appliances such as microwaves ovens, hair dryers and vacuum cleaners - are harmful to human health.

1 Aug 2011

New fluorescent tool can track mysterious workings of cellular RNAs

The ability to tag proteins with a green fluorescent light to watch how they behave inside cells so revolutionized the understanding of protein biology that it earned the scientific teams who developed the technique Nobel Prizes in 2008.

30 Jul 2011

NanoString introduces new assay for leukemia fusion gene analysis

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and developer of molecular diagnostics, today announced the availability of a comprehensive multiplexed assay for the simple and cost-effective analysis of fusion genes linked to leukemia.

From NanoString Technologies 29 Jul 2011

New silicone chip could make genetic analysis far more sensitive, rapid, and cost-effective

UBC researchers have invented a silicone chip that could make genetic analysis far more sensitive, rapid, and cost-effective by allowing individual cells to fall into place like balls in a pinball machine.

27 Jul 2011

Lipid-based nanocarrier can improve cancer treatments

Scientists seeking to improve cancer treatments have created a tiny drug transporter that maximizes its ability to silence damaging genes by finding the equivalent of an expressway into a target cell.

27 Jul 2011

Maltodextrin-based imaging probes could improve diagnosis and treatment of bacterial infections

A new family of contrast agents that sneak into bacteria disguised as glucose food can detect bacterial infections in animals with high sensitivity and specificity. These agents -- called maltodextrin-based imaging probes -- can also distinguish a bacterial infection from other inflammatory conditions.

21 Jul 2011

Humans and zebrafish share mechanisms that regulate the circadian system

Circadian rhythms - the natural cycle that dictates our biological processes over a 24-hour day - does more than tell us when to sleep or wake. Disruptions in the cycle are also associated with depression, problems with weight control, jet lag and more. Now Prof. Yoav Gothilf of Tel Aviv University's Department of Neurobiology at the George S. Wise Faculty of Life Sciences is looking to the common zebrafish to learn more about how the human circadian system functions.

21 Jul 2011

IHD blood test for Alzheimer's disease yields 83% sensitivity and 82% specificity

Innovative Health Diagnostics (IHD), the innovative company specialising in the development of diagnostic blood tests for Alzheimer's disease and neurodegenerative illnesses presents its first clinical results for its IHD-Amy blood test for Alzheimer's disease.

18 Jul 2011

DVS Sciences completes $14.6M series A financing

The Ontario Institute for Cancer Research (OICR) and DVS Sciences Inc., today announced that DVS Sciences has completed a $14.6 million series A financing.

14 Jul 2011

Light-switching complex could help detect signs of Alzheimer's disease

A breakthrough in sensing at Rice University could make finding signs of Alzheimer's disease nearly as simple as switching on a light.

14 Jul 2011

New method to study neuronal activity in the deepest layers of the cortex

Visual and tactile objects in our surroundings are translated into a perception by complex interactions of neurons in the cortex. The principles underlying spatial and temporal organization of neuronal activity during decision-making and object perception are not all understood yet.

13 Jul 2011

Broken compact fluorescent light bulbs can release harmful mercury vapor for a long time

Once broken, a compact fluorescent light bulb continuously releases mercury vapor into the air for weeks to months, and the total amount can exceed safe human exposure levels in a poorly ventilated room, according to study results reported in Environmental Engineering Science, a peer-reviewed online only journal published monthly by Mary Ann Liebert, Inc..

8 Jul 2011

New technique may help scientists probe mysteries of many different stem cells

Researchers at the Salk Institute have been able to genetically incorporate "unnatural" amino acids, such as those emitting green fluorescence, into neural stem cells, which then differentiate into brain neurons with the incandescent "tag" intact.

8 Jul 2011

Researchers identify cellular origin of malignant glioma

Using a mouse genetic system co-developed by researchers at the University of Oregon and Stanford University, a research team led by UO biologist Hui Zong has isolated the cellular origin for malignant glioma, a deadly human brain cancer.

8 Jul 2011

Fluorescence News and Research

MYCN amplification can serve as a favorable prognostic indicator for neuroblastoma

NPL scientists mimick the ways viruses infect human cells and deliver genetic material

New treatment uses lasers to stimulate stem cells and reduce heart scarring

Novel link between two receptors mediates fungal recognition in macrophages

Scientists identify small molecule inhibitors of cellular uptake

Chromogenic in situ hybridization can identify ALK rearrangement in lung cancer patients

Pregnancy and electromagnetic fields linked to asthma in kids

New fluorescent tool can track mysterious workings of cellular RNAs

NanoString introduces new assay for leukemia fusion gene analysis

New silicone chip could make genetic analysis far more sensitive, rapid, and cost-effective

Lipid-based nanocarrier can improve cancer treatments

Maltodextrin-based imaging probes could improve diagnosis and treatment of bacterial infections

Humans and zebrafish share mechanisms that regulate the circadian system

IHD blood test for Alzheimer's disease yields 83% sensitivity and 82% specificity

DVS Sciences completes $14.6M series A financing

Light-switching complex could help detect signs of Alzheimer's disease

New method to study neuronal activity in the deepest layers of the cortex

Broken compact fluorescent light bulbs can release harmful mercury vapor for a long time

New technique may help scientists probe mysteries of many different stem cells

Researchers identify cellular origin of malignant glioma

Fluorescence eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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