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Disrupted glucose transport in oligodendrocytes linked to myelin thinning and aging in new research

This study uncovers how oligodendroglial lipid metabolism supports myelin homeostasis and axonal function under metabolic stress, crucial for neurodegeneration.

11 Sep 2024

A fluorescent probe for studying serotonin in depression models

Serotonin in depression is highly relevant in diagnosis, treatment, and drug development. To better study this area, a Chinese team has now developed a fluorescent probe for imaging processes that is highly sensitive and selective toward serotonin.

6 Sep 2024

Breakthrough technology detects cancer mutant genes with unprecedented sensitivity

Dr. Min-young Lee and Dr. Sung-gyu Park of the Advanced Bio and Healthcare Materials Research Division at KIMS have developed a technology that can detect cancer mutant genes in blood with the world's highest sensitivity of 0.000000001% based on plasmonic nanomaterials for optical signal amplification.

6 Sep 2024

Scientists reveal how DNA methylation drives astrocytes to become stem cells, unlocking new potential for brain repair

Researchers have discovered that DNA methylation is crucial for reprogramming astrocytes into stem cells in the adult mouse brain, especially after ischemic injury, with potential implications for regenerative medicine.

6 Sep 2024

Electric current in gut attracts pathogens like Salmonella

Salmonella typhimurium's infection mechanism involves gut bioelectric signals, influencing its localization and interactions within the intestinal environment.

5 Sep 2024

A novel therapeutic option for HER2-positive extramammary Paget disease

The research article presents a comprehensive evaluation of the human epidermal growth factor receptor 2 (HER2) status in extramammary Paget disease (EMPD) and explores the therapeutic potential of disitamab vedotin (DV), a novel humanized anti-HER2 antibody-drug conjugate (ADC), for this rare adenocarcinoma.

4 Sep 2024

PQBP3 protein found to play key role in aging and brain disorders

In a recent study published online on August 5 2024 in The EMBO Journal, researchers from Tokyo Medical and Dental University (TMDU) in Japan have uncovered a crucial piece of this puzzle by focusing on the role of a single nucleolar protein.

3 Sep 2024

Nanodrug targeting miR-10b shows promise in treating metastatic breast cancer

A new research paper was published in Oncotarget's Volume 15 on August 26, 2024, entitled, "Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties."

29 Aug 2024

Novel biochip diagnoses deadly brain cancer in under an hour

Researchers at the University of Notre Dame have developed a novel, automated device capable of diagnosing glioblastoma, a fast-growing and incurable brain cancer, in less than an hour. The average glioblastoma patient survives 12-18 months after diagnosis.

28 Aug 2024

New technique enhances study of complex biological processes at the molecular level

A team of researchers led by Professor Sebastian Deindl at Uppsala University has developed a pioneering method that vastly improves the ability to observe and analyze complex biological processes at the single-molecule level.

23 Aug 2024

New technique speeds up screening of DNA molecules

Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs.

22 Aug 2024

New fluorescent probe offers non-invasive detection of smell loss

A new fluorescent imaging probe can for the first time objectively and non-invasively measure loss of smell, clinically known as anosmia.

20 Aug 2024

DeNovix releases new CellDrop model and applications

DeNovix announces the release of the new CellDrop FLi Automated Cell Counter, the latest update to the popular CellDrop range.

From DeNovix Inc. 14 Aug 2024

Lensless fluorescence detection system provides highly sensitive water quality assessment

Researchers have shown that a fluorescence detection system that doesn't contain any lenses can provide highly sensitive detection of deadly microorganisms in drinking water. With further development, the new approach could provide a low-cost and easy-to-use way to monitor water quality in resource-limited settings such as developing countries or areas affected by disasters. It could also be useful when water safety results are needed quickly, such as for swimming events, a concern highlighted during the Paris Olympics.

9 Aug 2024

ProDOL revolutionizes protein quantification in living cells

Scientists have developed a new way of counting labeled proteins in living cells that could become a standard and valuable tool in the field of biomedical research.

8 Aug 2024

Image-guided cancer treatment using biocompatible copper-based nanomaterials

Announcing a new article publication for BIO Integration journal. Cancer is a significant disease that poses a major threat to human health.

6 Aug 2024

Groundbreaking discovery reveals novel macrophages crucial for lung repair after viral infection

Researchers at the University of Liège (Belgium) have discovered a new population of macrophages, important innate immune cells that populate the lungs after injury caused by respiratory viruses.

2 Aug 2024

Advanced imaging techniques shed light on single cells

Every plant, animal, and person is a rich microcosm of tiny, specialized cells. These cells are worlds unto themselves, each with their own unique parts and processes that elude the naked eye.

2 Aug 2024

Novel electrical impedance technique enhances drug testing for cardiac safety

When developing new drugs, understanding their effects on ion channels in the body, such as the human ether-a-go-go-related gene (hERG) ion channel found in neurons and heart muscle cells, is critical.

1 Aug 2024

Researchers develop highly reactive RNA building blocks for enhanced chip production

An international research team led by the University of Vienna has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used in biotechnological and medical research. The chemical synthesis of these chips is now twice as fast and seven times more efficient. The results of the research were recently published in the prestigious journal Science Advances.

1 Aug 2024