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Researchers at the UJI increase the efficiency of photocatalysts used in cancer treatments

Researchers at the Universitat Jaume I (UJI) in Castellon have found porous polymeric materials that increase the efficiency of traditional photocatalysts in the treatment of cancer.

6 Apr 2009

Fluorescent anesthetic compound brings new avenues for drug discovery

A collaboration of University of Pennsylvania and University of Wisconsin chemists and anesthesiologists have identified a fluorescent anesthetic compound that will assist researchers in obtaining more precise information about how anesthetics work in the body and will provide a means to more rapidly test new anesthetic compounds in the search for safer and more effective drugs.

6 Apr 2009

Fluorescent cancer cells to guide brain surgeons

Gliomas are malignant brain tumors that arise from glial (supporting) cells of the brain.

5 Apr 2009

Researchers discover structure-building role for 2 non-coding RNAs

Most of the DNA in the nucleus of each of our cells is converted into RNA, but only a small fraction of these RNA molecules serve as coding templates for the synthesis of proteins.

2 Apr 2009

Basic guides to PCR, labeling neurons featured in Cold Spring Harbor Protocols

Along with new cutting-edge methods, Cold Spring Harbor Protocols is home to an in-depth library of basic laboratory methods.

1 Apr 2009

World's first nanofluidic device with complex 3-D surfaces

Researchers at the Commerce Department's National Institute of Standards and Technology (NIST) and Cornell University have capitalized on a process for manufacturing integrated circuits at the nanometer (billionth of a meter) level and used it to develop a method for engineering the first-ever nanoscale fluidic (nanofluidic) device with complex three-dimensional surfaces.

1 Apr 2009

CSHL neuroscientists propose project to comprehensively map mammalian brain circuits

Thirty-seven scientists from Cold Spring Harbor Laboratory (CSHL) and 20 other major research institutions in the U.S. and Europe have issued a major challenge to the neuroscience community.

1 Apr 2009

Genetic engineering breakthrough

In a genetic engineering breakthrough that could help everyone from bed-ridden patients to elite athletes, a team of American researchers - including 2007 Nobel Prize winner Mario R. Capecchi - have created a "switch" that allows mutations or light signals to be turned on in muscle stem cells to monitor muscle regeneration in a living mammal

30 Mar 2009

New radiation-free targeted therapy detects and eliminates breast cancer tumors in mice

Combining a compound known as a gallium corrole with a protein carrier results in a targeted cancer therapy that is able to detect and eliminate tumors in mice with seemingly fewer side effects than other breast-cancer treatments, says a team of researchers from the California Institute of Technology (Caltech), the Israel Institute of Technology (Technion) and the Cedars-Sinai Medical Center.

30 Mar 2009

Potential therapeutic strategy for fulminant hepatic failure

Fulminant hepatic failure is a serious clinical disease and may threaten the life of patients. However, because of the damage of mass liver cells, the organ function is often irreversible due to the liver cell degeneration, swelling, or apoptosis.

30 Mar 2009

New high-throughput screening technique makes probing puzzling proteins possible

Understanding the tens of thousands of proteins that compose the human proteome has emerged as a key challenge of this century, and research efforts to date have already enabled major advances in drug discovery and understanding basic biology.

29 Mar 2009

New discovery could lead to new methods to block the transmission of HIV

A team of researchers at Mount Sinai School of Medicine and the UC Davis Center for Biophotonics Science and Technology have for the first time captured on video the transfer of human immunodeficiency virus (HIV) from infected to uninfected T cells through structures called virological synapses.

29 Mar 2009

Nanoparticles in cosmetics may be harmful to the environment

Using aquatic microbes as their "canary-in-a-cage," scientists from Ohio have reported that nanoparticles now being added to cosmetics, sunscreens, and hundreds of other personal care products may be harmful to the environment.

29 Mar 2009

DNA repair mechanisms relocate in response to stress

Like doctors making house calls, some DNA repair enzymes can relocate to the part of the cell that needs their help, a collaborative team of scientists at Emory University School of Medicine has found.

29 Mar 2009

New tuberculosis test dramatically cuts diagnosis time

Researchers from the Albert Einstein College of Medicine and The University of Pittsburgh have developed an onsite method to quickly diagnose tuberculosis (TB) and expose the deadly drug-resistant strains that can mingle undetected with treatable TB strains.

20 Mar 2009

Researchers create onsite method to quickly diagnose tuberculosis

Researchers from the University of Pittsburgh and the Albert Einstein College of Medicine have developed an onsite method to quickly diagnose tuberculosis (TB) and expose the deadly drug-resistant strains of Mycobacterium tuberculosis that can mingle undetected with treatable strains.

20 Mar 2009

Scientists 'watch' as individual alpha-synuclein proteins change shape

In an Early Edition publication of The Proceedings of the National Academy of Sciences (PNAS) this week, the researchers demonstrate the "alpha-synuclein dance" - the switching back and forth of the protein between a bent helix and an extended helix as the surface that it is binding to changes.

16 Mar 2009