Fluorescence News and Research

RSS

Researchers use DNA to drive the assembly of 3D gold structures

DNA is the blueprint of all life, giving instruction and function to organisms ranging from simple one-celled bacteria to complex human beings.

4 Feb 2008

Weakness found in anthrax bacterium

MIT and New York University researchers have identified a weakness in the defenses of the anthrax bacterium that could be exploited to produce new antibiotics.

25 Jan 2008

DNA sensors found to be an effective artificial nose

In designing artificial noses modeled after biological olfaction, the challenge has been to generate a similarly large sensor repertoire with the requisite combinatorial complexity to detect odors in the real world.

24 Jan 2008

Genetic switches could lower cost of producing drugs, proteins

Bacteria have evolved complex mechanisms called quorum sensing systems that provide for cell-to-cell communication, an adaptation that allows them to wait until their population grows large enough before mounting an attack on a host or competing for nutrients.

23 Jan 2008

Stem cell therapy restores muscle function in mice with muscular dystrophy

Scientists in Texas have been able to restore muscle function in mice with muscular dystrophy by using embryonic stem cells.

21 Jan 2008

Stem-cell transplantation improves muscles in MD animal model

Using embryonic stem cells from mice, UT Southwestern Medical Center researchers have prompted the growth of healthy - and more importantly, functioning - muscle cells in mice afflicted with a human model of Duchenne muscular dystrophy.

21 Jan 2008

Matrix metalloproteinase-assisted triggered release of liposomal contents

Cancer cells display a variety of proteins on their outer membranes that are not present on the surface of normal cells.

16 Jan 2008

Cancer cell targeting using multiple aptamers conjugated on nanorods

Aptamers, short stretches of DNA or RNA that can act much like antibodies, have shown promise as targeting agents for selective nanoparticle trafficking to tumors.

16 Jan 2008

Researchers find new way to block destructive rush of immune cells

Researchers have found a way to selectively block the ability of white blood cells to "crawl" toward the sites of injury and infection when such mobility drives disease, according to a study published today in The Journal of Experimental Medicine.

15 Jan 2008

U.S. Food and Drug Administration approves new genetic breast cancer test

The U.S. Food and Drug Administration has approved a test that helps in assessing the risk of tumor recurrence and long-term survival for patients with relatively high-risk breast cancer. The TOP2A FISH pharmDx is the first approved device to test for the TOP2A (topoisomerase 2 alpha) gene in cancer patients.

14 Jan 2008

New understanding on the mechanics of gene transcription

The molecular machinery behind gene transcription -- the intricate transfer of information from a segment of DNA to a corresponding strand of messenger RNA -- isn't stationed in special "transcription factories" within a cell nucleus, according to Cornell researchers.

9 Jan 2008

Insights into cell movement likely to aid immune study, cancer research

Scientists at Washington University School of Medicine in St. Louis have used yeast cells to better understand a collection of proteins associated with the formation of actin networks, which are essential to cell movement.

9 Jan 2008

Biochemist wins grant to develop cellular molecular probes capable of measuring cholesterol levels

Alejandro P. Heuck, a biochemist at the University of Massachusetts Amherst, has received a four-year, $308,000 grant from the American Heart Association to develop molecular probes capable of measuring cholesterol levels in the membranes of individual cells.

7 Jan 2008

Energy efficient bulbs blamed for triggering migraines

According to a British migraine lobby group, energy efficient light bulbs could be causing migraines.

3 Jan 2008

Intracellular bacterial communities in cystitis; rifapentine cures TB in mouse model; and more

A study published this week in the open access journal PLoS Medicine presents convincing evidence that intracellular bacterial communities (IBCs) commonly exist in women with bladder infections and may contribute to the recurrence of these infections.

18 Dec 2007

Breakthrough technology provides new understanding of cellular processes endocytosis and exocytosis

For the first time, scientists at Weill Cornell Medical College in New York City have observed in real time a cellular mechanism that's crucial to how brain cells communicate.

17 Dec 2007

Researchers report protein interactions of MAP kinase signaling pathway

The Stowers Institute's Rong Li Lab, in collaboration with the Institute's Imaging Center, has achieved a quantitative in vivo measurement of the dynamic protein-protein interactions in the mitogen-activated protein (MAP) kinase cascade signaling pathway, which is critical to growth and differentiation decisions in all eukaryotic cells.

14 Dec 2007

Researchers shine the light of venus to learn how the herpes virus invades cells

University of Pennsylvania researchers have uncovered an important step in how herpes simplex virus, HSV-1, uses cooperating proteins found on its outer coat to gain entry into healthy cells and infect them.

14 Dec 2007

First view of synapse in real time

For the first time, scientists at Weill Cornell Medical College in New York City have observed in real time a cellular mechanism that's crucial to how brain cells communicate.

14 Dec 2007

Odyssey Thera granted U.S. patent for animal imaging

Odyssey Thera, Inc. has announced that the United States Patent and Trademark Office granted U.S. Patent No. 7,306,914, entitled "Protein-fragment Complementation Assays (PCA) in whole animals: applications to drug efficacy, ADME, cancer biology, immunology, infectious disease and gene therapy.

13 Dec 2007