Fluorescence Microscopy News and Research

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Fluorescence microscopy is an imaging technique used to examine cells and their internal components. Specific cellular components can be labeled with fluorophores.

Scientists record assembly of ribosomes in real time

A team of scientists from Scripps Research and Stanford University has recorded in real time a key step in the assembly of ribosomes--the complex and evolutionarily ancient "molecular machines" that make proteins in cells and are essential for all life forms.

22 Nov 2019

KAUST researchers one step closer to understanding brain function

Researchers at King Abdullah University of Science and Technology (KAUST) are officially one-step closer to understanding the brain and its function.

29 Oct 2019

Bruker Introduces Light-Sheet Microscope for Fast Imaging of Very Large Optically Cleared Samples

At Neuroscience 2019, the 49th annual meeting of the Society for Neuroscience, Bruker (Nasdaq: BRKR) today announced the release of the Luxendo LCS SPIM light-sheet fluorescence microscope for fast 3D imaging of large, optically cleared samples.

From Bruker Nano Surfaces and Metrology 22 Oct 2019

Research may help explain how liquid organelles in cells coexist without merging

New research may help to explain an intriguing phenomenon inside human cells: how wall-less liquid organelles are able to coexist as separate entities instead of just merging together.

10 Oct 2019

How do gallstones form?

The human body is known to produce stones in various locations, most commonly in the kidneys, the bladder, the gallbladder and the appendix. Many of these stones appear without any obvious reason. However, a new study published in the journal Immunity shows the whole storyline for the first time: how gallstones are formed.

9 Oct 2019

High-resolution imaging shows how HIV spreads between living cells

In order to treat diseases better, we must understand how they arise.

3 Oct 2019

Findings could open up new research avenues into how heme tolerance occurs in humans

Most people have some idea of how important iron is to their health, but Iqbal Hamza, professor in Animal and Avian Sciences, has made his seventeen-year career at the University of Maryland all about the study of iron and heme trafficking and regulation in the body.

1 Oct 2019

New technique can rapidly image synaptic proteins at high resolution

Our brains contain millions of synapses -- the connections that transmit messages from neuron to neuron. Within these synapses are hundreds of different proteins, and dysfunction of these proteins can lead to conditions such as schizophrenia and autism.

26 Sep 2019

Innovative method could improve understanding of many processes in the body at molecular level

Cells are the basic building blocks of life - and, as such, they have been the object of intense study since the invention of the optical microscope in the 17th century.

7 Sep 2019

Study: Megakaryocytes play an important role in cell migration

Hematopoiesis is the process of forming blood cells, which occurs predominantly in the bone marrow. The bone marrow produces all types of blood cells: red blood cells, platelets, and white blood cells.

18 Jul 2019

Tomocube HT microscope enables label-free quantification of cellular lipid content

In a breakthrough for research fields as diverse as diabetes, atherosclerosis and biofuels, the mass, concentration, volume, and surface area of individual lipid droplets have been measured in live, unstained cells for the first time using a Tomocube Holotomography microscope.

From Tomocube Inc. 12 Jul 2019

Blink and you miss it: Imaging single cells travelling at the speed of Usain Bolt

A new review has summarized recent research into the development of ultra-high-throughput single cell analysis and multi-parametric imaging tools.

6 Jun 2019

Scientists describe how cells 'decide' between pluripotency and differentiation

Induced pluripotent stem cells can turn into any type of cell in the body or remain in their original form. In the current edition of Molecular Cell, scientists from the Helmholtz Zentrum München describe how cells “decide” which of these two directions to take.

3 May 2019

Brazilian researchers reveal bactericidal action mechanism of violacein

In an article published in the journal ACS Infectious Diseases, Brazilian researchers describe the bactericidal action mechanism of violacein, a violet pigment produced by environmental bacteria, especially Chromobacterium violaceum.

26 Apr 2019

Holotomography (HT) technology used to image individual neurons

A Korean research team has demonstrated quantitative morphological profiling of individual neurons using Holotomography (HT) technology developed by Tomocube.

From Tomocube Inc. 14 Mar 2019

$2.7 million grant supports UIC researchers to study role of arsenic in development of diabetes

A five-year, $2.7 million grant from the National Institute of Environmental Health Sciences will help researchers at the University of Illinois at Chicago answer basic questions about the role of arsenic in the development of diabetes and examine the mechanisms by which selenoproteins – found in the human body in 25 different forms – counter the effects of arsenic.

11 Mar 2019

Researchers examine process of gut-based cells involved in long-term immunity

Only a few vaccines - for example, against polio and rotavirus - can be given orally. Most must be delivered by injection.

5 Mar 2019

Novel Imaging Methods for Biomedicine

Wei Min has been awarded the Pittcon 2019 Achievement Award. In this interview, he outlines the current imaging challenges in biomedicine and how his novel chemical imaging methods can overcome these.

From Pittcon 26 Feb 2019

Study: BldC protein in Streptomyces acts as ‘brake’ to control timing of sporulation

Streptomyces are soil-dwelling bacteria that produce approximately two-thirds of the antibiotics in current clinical use.

6 Feb 2019

Researcher discovers blood vessel system in bones

A network of very fine blood vessels that connects bone marrow directly with the blood supply of the periosteum that was previously overlooked has now been discovered by Dr. Anika Grüneboom, a young researcher who is now working at Universitätsklinikum Erlangen.

30 Jan 2019