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Bioethics Commission releases ethical recommendations to manage incidental and secondary findings

Researchers conduct a memory study, scan a participant's brain, and find more than they bargain for: a tumor. What do the researchers owe the participant? What does the participant want to know?

13 Dec 2013

Airway alterations present even in young smokers without COPD

A study has found functional and inflammatory changes in the nasal and lower airways of young, healthy smokers in the absence of pulmonary function decline.

12 Dec 2013

Climate differences drive gene changes, find Virginia Bioinformatics Institute researchers

Interplay between genes and the environment has been pondered at least since the phrase "nature versus nurture" was coined in the mid-1800s.

12 Dec 2013

New algorithm separates signals into individual frequencies using minimal number of samples

The fast Fourier transform, one of the most important algorithms of the 20th century, revolutionized signal processing. The algorithm allowed computers to quickly perform Fourier transforms - fundamental operations that separate signals into their individual frequencies - leading to developments in audio and video engineering and digital data compression.

12 Dec 2013

Study: Girls in single-sex schools feel more pressure to act like "typical girls"

Newspaper headlines worldwide tout the benefits of single-sex schools: Girls 75% more likely to take math if they go to a single-sex private school, Will boys learn better if girls aren't allowed? Single-sex education is best for girls in stereotypically male subjects.

12 Dec 2013

First patient enrolled in Otonomy's pivotal Phase 2b study of OTO-104 for Meniere's disease

Otonomy, Inc., a clinical stage biopharmaceutical company developing innovative therapeutics for diseases and disorders of the inner and middle ear, today announced enrollment of the first patient in its pivotal Phase 2b study of OTO-104 for the reduction of vertigo in patients with unilateral Meniere's disease.

11 Dec 2013

Antibody-toxin compound shows compelling antitumor activity in non-Hodgkin lymphomas patients

A toxin linked to a targeted monoclonal antibody has shown "compelling" antitumor activity in patients with non-Hodgkin lymphomas who were no longer responding to treatment, according to a report from Dana-Farber Cancer Institute.

11 Dec 2013

Endocrinologist suggests parents to check their child's blood sugar more often during holidays

Indulgences abound during the holidays—from family gatherings to parties with friends and even stockings stuffed with goodies from Santa. For children with diabetes, overindulging on the delicacies of the season could result in more than a stomach ache, it could mean a trip to the emergency room.

10 Dec 2013

Biosimulation and epilepsy treatments: an interview with Dr. Serge Bischoff, CEO of Rhenovia and RHENEPI program director

The need for biosimulation is primarily to do with the very high attrition rate in drug development and especially in the development of drugs for the central nervous system.

10 Dec 2013

FoundationOne Heme identifies clinically actionable genomic alterations in multiple myeloma cases

Foundation Medicine today announced new data from a pilot study demonstrating that its fully informative genomic profile for hematologic malignancies, FoundationOne Heme, identified both novel and previously reported clinically actionable genomic alterations in multiple myeloma cases. These data were presented in an oral presentation titled Pilot Study To Evaluate The Prevalence Of Actionable Oncogenic Mutations In Patients With Relapsed Refractory Multiple Myeloma (abstract number 755) by Alexander Lesokhin, M.D., medical oncologist, Memorial Sloan-Kettering Cancer Center, at the 55th American Society of Hematology Annual Meeting in New Orleans.

10 Dec 2013

Researchers use popular music to help severely brain-injured patients recall personal memories

In the first study of its kind, two researchers have used popular music to help severely brain-injured patients recall personal memories. Amee Baird and Séverine Samson outline the results and conclusions of their pioneering research in the recent issue of the journal Neuropsychological Rehabilitation.

10 Dec 2013

Orthogonal design to sift optimal parameter of Neiguan acupuncture

The individual difference and non-repeatability in acupuncture have not only restricted the development of acupuncture, but have also affected the specificity of acupoints.

10 Dec 2013

New findings on effects of epilepsy on mother and child

New research pertaining to the latest findings on the effects of epilepsy on both the mother and child were presented at the American Epilepsy Society's 67th Annual Meeting in Washington DC. These studies explore folic acid use, the effect of surgery with intractable focal epilepsy, and antiepileptic drug exposure during breastfeeding.

10 Dec 2013

Exercise program improves symptoms of depression in patients with Parkinson's disease

A new study by a movement disorder neurologist at The Ohio State University Wexner Medical Center found that depression improved among patients with Parkinson's disease who participated in a long-term group exercise program.

10 Dec 2013

Arrowhead reports Phase 1 study data on ARC-520 for treatment of chronic hepatitis B infection

Arrowhead Research Corporation, a biopharmaceutical company developing targeted RNAi therapeutics, today announced that COO and Head of R&D, Bruce Given, M.D., presented data on the Phase 1 clinical study of ARC-520, the company's clinical candidate for the treatment of chronic hepatitis B infection, at the HepDART 2013 conference being held on The Big Island, Hawaii.

9 Dec 2013

Research explores epigenetic effects that contribute to psychiatric disorders in offspring

Advanced paternal age has been associated with greater risk for psychiatric disorders, such as schizophrenia and autism. With an increase in paternal age, there is a greater frequency of certain types of mutations that contribute to these disorders in offspring.

9 Dec 2013

Frequency News and Research

Bioethics Commission releases ethical recommendations to manage incidental and secondary findings

Airway alterations present even in young smokers without COPD

Climate differences drive gene changes, find Virginia Bioinformatics Institute researchers

New algorithm separates signals into individual frequencies using minimal number of samples

Study: Girls in single-sex schools feel more pressure to act like "typical girls"

First patient enrolled in Otonomy's pivotal Phase 2b study of OTO-104 for Meniere's disease

Antibody-toxin compound shows compelling antitumor activity in non-Hodgkin lymphomas patients

Endocrinologist suggests parents to check their child's blood sugar more often during holidays

Biosimulation and epilepsy treatments: an interview with Dr. Serge Bischoff, CEO of Rhenovia and RHENEPI program director

FoundationOne Heme identifies clinically actionable genomic alterations in multiple myeloma cases

Researchers use popular music to help severely brain-injured patients recall personal memories

Orthogonal design to sift optimal parameter of Neiguan acupuncture

New findings on effects of epilepsy on mother and child

Exercise program improves symptoms of depression in patients with Parkinson's disease

Arrowhead reports Phase 1 study data on ARC-520 for treatment of chronic hepatitis B infection

Research explores epigenetic effects that contribute to psychiatric disorders in offspring

LUTS likely to resolve without treatment

Insomnia linked to increased GERD risk

Majority of epilepsy surgery patients satisfied with results in improving psychological and social well-being

Study demonstrates safety and efficacy of NeuroPace RNS System in adults with intractable seizures

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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