Frontotemporal Dementia News and Research

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Scientists discover novel protein fragments that may protect against Alzheimer's disease

The devastating loss of memory and consciousness in Alzheimer's disease is caused by plaque accumulations and tangles in neurons, which kill brain cells.

14 May 2014

Mayo Clinic neuroscientists define subtype of Alzheimer's disease

Neuroscientists at Mayo Clinic in Florida have defined a subtype of Alzheimer's disease (AD) that they say is neither well recognized nor treated appropriately.

2 May 2014

Bristol-Myers Squibb completes acquisition of iPierian

Bristol-Myers Squibb Company and iPierian, Inc. announced today that Bristol-Myers Squibb has acquired iPierian, a privately held biotechnology company focused on the discovery and development of new treatments for Tauopathies, a class of neurodegenerative diseases associated with the pathological aggregation of Tau protein in the human brain.

29 Apr 2014

New findings shed light on how gene mutation causes motor neurone disease

Researchers have discovered a mechanism that may explain how a recently discovered mutation causes two devastating neurological diseases.

6 Mar 2014

New findings shed light on how gene mutation causes motor neurone disease

Researchers have discovered a mechanism that may explain how a recently discovered mutation causes two devastating neurological diseases.

6 Mar 2014

Increased brain cell activity boosts protein linked to Alzheimer's disease

Increased brain cell activity boosts brain fluid levels of a protein linked to Alzheimer's disease, according to new research from scientists at Washington University School of Medicine in St. Louis.

26 Feb 2014

Glimmer of hope for Alzheimer’s disease sufferers

Hope may be on its way for sufferers of Alzheimer’s Disease as the Griffith Health Institute seeks participants for new research.

7 Feb 2014

TauRx Therapeutics adds new research centers across U.S. for Alzheimer’s clinical trials

TauRx Therapeutics Ltd, a clinical-stage biopharmaceutical company developing a novel treatment for Alzheimer's disease, has expanded its international clinical trials by adding new research centers across the U.S.

6 Jan 2014

Researchers identify novel therapeutic approach for most frequent genetic cause of ALS

A team of scientists led by researchers from the University of California, San Diego School of Medicine and Ludwig Institute for Cancer Research have identified a novel therapeutic approach for the most frequent genetic cause of ALS, a disorder of the regions of the brain and spinal cord that control voluntary muscle movement, and frontal temporal degeneration, the second most frequent dementia.

10 Nov 2013

Study: Speaking a second language may delay onset of three types of dementias

In the largest study on the topic to date, research shows that speaking a second language may delay the onset of three types of dementias. The research is published in the November 6, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Nov 2013

Scientists identify new toxic entity associated with dementia and motor neuron disease

A new toxic entity associated with genetically inherited forms of dementia and motor neuron disease has been identified by scientists at the UCL Institute of Neurology. The toxin is the result of a genetic mutation that leads to the production of RNA molecules which could be responsible for the diseases. The findings are published in the journal Acta Neuropathologica.

31 Oct 2013

Newly opened Manchester-based DNA bank may support discoveries on motor neuron disease

A specialist DNA Bank, based at The University of Manchester, is now open to the worldwide research community, supporting more crucial discoveries about motor neurone disease (MND), a devastating terminal illness.

5 Oct 2013

Researchers identify alterations in proteins responsible for RNA splicing in Alzheimer's

Researchers at Emory University School of Medicine's Alzheimer's Disease Research Center have identified a previously unrecognized type of pathology in the brains of patients with Alzheimer's disease.

11 Sep 2013

NIHR recognizes Plymouth Hospitals for promoting clinical research in NHS

Healthcare professionals and academic researchers will have the opportunity to hear from research teams at Plymouth Hospitals NHS Trust and its research partners next month.

30 Aug 2013

Researchers identify possible treatment strategy for ALS and other neurodegenerative disorders

Researchers have tied mutations in a gene that causes amyotrophic lateral sclerosis and other neurodegenerative disorders to the toxic buildup of certain proteins and related molecules in cells, including neurons. The research, published recently in the scientific journal Cell, offers a new approach for developing treatments against these devastating diseases.

29 Aug 2013

Frontotemporal dementia (FTD) and emotional memories: an interview with Dr. Fiona Kumfor and Assoc. Prof. Olivier Piguet, NeuRA

Frontotemporal dementia (FTD) is a progressive neurodegenerative brain disorder, which affects the frontal and temporal lobes. Unlike other types of dementia, it more commonly occurs in individuals in their 50s and 60s, and is therefore referred to as a “younger-onset dementia”.

9 Aug 2013

NeuRA study demonstrate that FTD patients lose emotional content/colour of memories

A study by researchers at Neuroscience Research Australia is the first to demonstrate that patients with frontotemporal dementia lose the emotional content/colour of their memories. These findings explain why FTD patients may not vividly remember an emotionally charged event like a wedding or funeral.

15 Jul 2013

NeuRA study: Orbitofrontal cortex plays key role in linking emotion, memories in FTD patients

A study by researchers at Neuroscience Research Australia (NeuRA) is the first to demonstrate that patients with frontotemporal dementia (FTD) lose the emotional content/colour of their memories. These findings explain why FTD patients may not vividly remember an emotionally charged event like a wedding or funeral.

9 Jul 2013

MGH researchers discover CNVs in members of 10 families with early-onset Alzheimer's

Although a family history of Alzheimer's disease is a primary risk factor for the devastating neurological disorder, mutations in only three genes - the amyloid precursor protein and presenilins 1 and 2 - have been established as causative for inherited, early-onset Alzheimer's, accounting for about half of such cases.

18 Jun 2013

Mouse study shows leukemia halts accumulation of toxic proteins linked to Parkinson's disease

Researchers at Georgetown University Medical Center have used tiny doses of a leukemia drug to halt accumulation of toxic proteins linked to Parkinson's disease in the brains of mice. This finding provides the basis to plan a clinical trial in humans to study the effects.

10 May 2013

Frontotemporal Dementia News and Research

Scientists discover novel protein fragments that may protect against Alzheimer's disease

Mayo Clinic neuroscientists define subtype of Alzheimer's disease

Bristol-Myers Squibb completes acquisition of iPierian

New findings shed light on how gene mutation causes motor neurone disease

New findings shed light on how gene mutation causes motor neurone disease

Increased brain cell activity boosts protein linked to Alzheimer's disease

Glimmer of hope for Alzheimer’s disease sufferers

TauRx Therapeutics adds new research centers across U.S. for Alzheimer’s clinical trials

Researchers identify novel therapeutic approach for most frequent genetic cause of ALS

Study: Speaking a second language may delay onset of three types of dementias

Scientists identify new toxic entity associated with dementia and motor neuron disease

Newly opened Manchester-based DNA bank may support discoveries on motor neuron disease

Researchers identify alterations in proteins responsible for RNA splicing in Alzheimer's

NIHR recognizes Plymouth Hospitals for promoting clinical research in NHS

Researchers identify possible treatment strategy for ALS and other neurodegenerative disorders

Frontotemporal dementia (FTD) and emotional memories: an interview with Dr. Fiona Kumfor and Assoc. Prof. Olivier Piguet, NeuRA

NeuRA study demonstrate that FTD patients lose emotional content/colour of memories

NeuRA study: Orbitofrontal cortex plays key role in linking emotion, memories in FTD patients

MGH researchers discover CNVs in members of 10 families with early-onset Alzheimer's

Mouse study shows leukemia halts accumulation of toxic proteins linked to Parkinson's disease

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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