G Protein Coupled Receptor News and Research

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GRK5's role in restenosis

Researchers at Jefferson Medical College have begun to clarify the role of a protein - and potential drug target - in the process by which arteries re-clog after treatment.

28 Nov 2005

GRK2 protein - potential drug target for heart failure

A protein that plays an important regulatory role in heart failure in the heart also exerts powerful effects on the adrenal gland, Jefferson Medical College researchers have found. The protein, GRK2, is a potential drug target for heart failure.

28 Nov 2005

Arena Pharmaceuticals issue new patent

Arena Pharmaceuticals has announced that it was issued US patent number 6,953,787, entitled "5-HT2C Receptor Modulators," by the United States Patent and Trademark Office.

11 Oct 2005

Research shows key difference between the eye's light-detecting system and the nose's odor-detecting system

Johns Hopkins scientists have uncovered new details of how smelly things create signals in the nose that eventually go to the brain. The findings raise issues about how the process involved has been described for many years in biology textbooks.

13 Jul 2005

Arena Pharmaceuticals issued new patent

Arena Pharmaceuticals has announced that it was issued U.S. patent number 6,902,902, entitled "Human G Protein-Coupled Receptors and Modulators Thereof for the Treatment of Metabolic-Related Disorders," by the U.S. Patent Office.

8 Jun 2005

Nephrogenic Syndrome of Inappropriate Antidiuresis - a new genetic disease

Two infant boys whose bodies were overloaded with excess fluid have led UCSF pediatricians to the discovery of a new genetic disease. In the process, they have discovered a rare type of mutation where different substitutions in a single amino acid cause two different, opposite genetic disorders.

4 May 2005

Brain protein called MC4R that plays a role in the urge to eat has now been found to influence appetite in a second way

A brain protein already known to play a central role in the "feast or fast" signaling that controls the urge to eat has now been found to influence appetite in a second way. The discovery identifies a potential new target for drugs against obesity.

19 Oct 2004

Zinc plays a crucial role in blindness

Dartmouth Medical School researchers in their quest to find cures for inherited diseases have found that zinc plays a crucial role in blindness in over one million people worldwide.

18 Aug 2004

Discovery of new gene sheds light on human brain development

With the identification of the gene responsible for a newly recognized type of mental retardation, researchers at Beth Israel Deaconess Medical Center (BIDMC) have also discovered what appears to be the key target in the evolution of the frontal lobes of the brain's cerebral cortex. The findings offer a key insight into the complex puzzle of human brain development - and the evolution of human behavior.

25 Mar 2004