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Tirzepatide improves body composition across a range of adult age groups, study shows

A new analysis of SURMOUNT-1, the first Phase 3 study of tirzepatide in adults for chronic weight management shows that tirzepatide improves body composition across a range of adult age groups.

19 May 2023

What is the association between obesity and insulin resistance in youth and its production of colon-derived acetate, gut-derived hormone secretion, and adipose tissue lipolysis?

Researchers assessed whether insulin resistance and adiposity in youth were linked to the fermentation of dietary fibers.

11 May 2023

Boosting gut health with short-chain fatty acids

Research paper provides an overview of short-chain fatty acids (SCFAs) and their role in regulating gut homeostasis. It also discusses SCFA-producing bacteria and potential therapeutic approaches to boost SCFA levels in the gut to treat related diseases.

9 May 2023

Insights from experts on the neurobiological processes involved in appetite regulation

Researchers summarized the main findings related to the neurobiological regulation of appetite presented at the 23rd Harvard Nutrition Obesity Symposium in June 2022.

8 May 2023

Study evaluates simultaneous effects of exercise and diet-induced weight reduction in patients with type 2 diabetes

Researchers performed a four-armed, 16-week randomized clinical trial on type II diabetes.

3 May 2023

Experimental anti-obesity drug may control appetite without surgery or nausea

Imagine getting the benefits of gastric bypass surgery without going under the knife -; a new class of compounds could do just that. In lab animals, these potential treatments reduce weight dramatically and lower blood glucose.

29 Mar 2023

Childhood and adolescent obesity: time to act

In a recent review published in the journal Frontiers in Pediatrics, researchers at the Medical College of Wisconsin presented an overview of the pathophysiological mechanisms, health implications, and management options for obesity among children and adults.

21 Mar 2023

Loss of a beta cell subset might contribute to type 2 diabetes

Multiple types of beta cells produce insulin in the pancreas, helping to balance blood sugar levels. Losing a particularly productive type of beta cell may contribute to the development of diabetes, according to a new study by Weill Cornell Medicine investigators.

17 Mar 2023

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Researchers investigate the impact of intestinal microbiota dysbiosis on atherosclerotic cardiovascular disease incidence.

15 Mar 2023

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

The hormone glucose-dependent insulinotropic polypeptide (GIP) is considered obesogenic. In contrast, GIP receptor agonists (GIPRAs) have shown reduced feeding and body weight in an obese mouse model. Therefore, the precise effects exerted by GIP and GIPRAs remain elusive.

14 Mar 2023

Injectable peptide used for type 2 diabetes shows potential for treating 'blinding' IIH headaches

Patients with 'blinding' headaches known as Idiopathic Intercranial Hypertension could be treated with an injectable peptide used for type 2 diabetes, a new trial has found.

13 Mar 2023

How gut microbiota control feelings of fullness after eating

A recent study discusses recent findings linking satiety to the gut microbiome.

7 Mar 2023

Are SGLT2 inhibitors the next blockbuster drug?

Recent clinical trials investigating the therapeutic potency of sodium-glucose cotransporter 2 inhibitors (SGLT2i) have highlighted that this drug is highly effective in treating patients with cardiovascular and renal diseases.

19 Feb 2023

Revised guidelines for diabetes care

A recent Diabetes Care journal paper summarized the latest recommendations offered to people with diabetes to improve their health and well-being.

15 Dec 2022

Patients complain some obesity care startups offer pills, and not much else

Many Americans turn to the latest big idea to lose weight — fad diets, fitness crazes, dodgy herbs and pills, bariatric surgery, just to name a few. They're rarely the magic solution people dream of.

15 Nov 2022

Is there a right time for eating?

In a recent study published in the journal Cell Metabolism, researchers assessed how calorie or energy intake (EI) time influences calorie distribution and all energy expenditure (EE) components, which, in turn, impact energy balance and weight loss in healthy obese people.

12 Sep 2022