Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Statins reduce risk of colon and rectal cancers: Study

A systematic review of the medical literature supports the hypothesis that statins, cholesterol‐lowering drugs used to prevent cardiac problems, are associated with reduced risk of colon and rectal cancers. A comprehensive analysis by investigators at the University of Michigan at Ann Arbor, included 22 scientific studies with more than 2.5 million combined participants.

18 Oct 2010

Studies explore impact of upper GI conditions on sleep

The impact of upper GI conditions, like gastroesophageal reflux disease (GERD) and functional dyspepsia, on sleep—and treatments aimed at providing relief to heartburn/acid reflux patients who suffer from disordered sleep—were explored in three new studies related to sleep dysfunction presented today at the American College of Gastroenterology's (ACG) 75th Annual Scientific meeting in San Antonio, Texas.

18 Oct 2010

Retroflexion in right colon increases yield of polyps in proximal colon

Research exploring the progression of colon polyps to colorectal cancer and evaluating techniques to improve polyp detection was among the clinical science presented at the 75th Annual Scientific Meeting of the American College of Gastroenterology in San Antonio today.

18 Oct 2010

IBD patients with Vitamin D deficiency at greater risk of osteoporosis, osteopenia

Vitamin D deficiency puts patients with Inflammatory Bowel Disease (IBD) at greater risk of osteoporosis, osteopenia and an overall higher rate of abnormal bone density, according to the results of a new study unveiled today at the American College of Gastroenterology's (ACG) 75th Annual Scientific meeting in San Antonio, Texas.

18 Oct 2010

Fluticasone gets rid of eosinophils in the esophagus, but does not improve symptoms

A group of Mayo Clinic researchers conducted the first controlled trial of swallowed fluticasone nasal spray (also known as Flonase) on people with the allergic esophageal condition called eosinophilic esophagitis. Research showed that the aerosolized swallowed allergy drug helped treat the cause of the throat condition, but symptoms lingered. The researchers' findings were presented today at the Annual Scientific Meeting of the American College of Gastroenterology in San Antonio.

18 Oct 2010

Hyperion's HPN-100 granted FDA Fast Track Designation for urea cycle disorders

Hyperion Therapeutics, Inc. announced today that its investigational compound glycerol phenylbutyrate (HPN-100) has been granted Fast Track Designation by the U.S. Food and Drug Administration (FDA) as adjunctive therapy for the chronic management of urea cycle disorders. Hyperion recently completed its phase III trial which was conducted under a Special Protocol Assessment (SPA) agreement with the FDA. The Company plans to announce results from that trial later this year.

18 Oct 2010

Preliminary Phase 2 data of TZP-102 for diabetic gastroparesis to be presented at ACG annual meeting

Tranzyme Pharma announced today that John Wo, MD, Professor of Medicine and Director, Clinical Research, Division of Gastroenterology, Hepatology and Nutrition, University of Louisville, Louisville, KY, will present preliminary TZP-102 Phase 2 data at this year's ACG annual meeting. The event is being held at the Henry B. Gonzalez Convention Center in San Antonio TX, October 15-20, 2010. Professor Wo is scheduled to speak on Wednesday, October 20th at 8:50am in Ballroom C1.

18 Oct 2010

ACG meeting to exhibit Cimzia data for Crohn's disease treatment

Studies and analyses of the Crohn's disease (CD) treatment Cimzia (certolizumab pegol) will be exhibited at the 2010 Annual Scientific Meeting of the American College of Gastroenterology, taking place in San Antonio from October 15 – 20.

18 Oct 2010

Series of pan-endoscopies show unparalleled ability to navigate intestinal tract

Spirus Medical, Inc. a leading developer of diagnostic and therapeutic advancement systems for gastroenterology announces a series of pan-endoscopies in an average time of 60 minutes, using a flexible endoscope with an integral drive to power a single use spiral component. The initial clinical series, which was conducted outside the U.S., showed unparalleled ability to navigate the intestinal tract.

18 Oct 2010

Sinai Hospital physician honored at ACG's annual scientific meeting

Sudhir K. Dutta, M.D. head of the Division of Gastroenterology at Sinai Hospital, was awarded the designation "Master of the American College of Gastroenterology" at the ACG's annual scientific meeting today.

18 Oct 2010

Heavy drinking during pregnancy associated with serious developmental defects in fetus

Scientific data continue to indicate that higher intake of alcohol during pregnancy adversely affects the fetus, and could lead to very severe developmental or other problems in the child. However, most recent publications show little or no effects of occasional or light drinking by the mother during pregnancy.

15 Oct 2010

Caris Life Sciences presents new diagnostic data at ACG 2010

Caris Life Sciences, Inc., a leading biosciences company focused on enabling precise and personalized healthcare through the highest quality anatomic pathology, molecular profiling and blood-based diagnostic technologies, today announced upcoming highlights from the Company's presentations at the 2010 Annual Meeting of the American College of Gastroenterology ("ACG 2010") held in San Antonio, TX, October 15-20. In total, Caris was awarded 17 accepted abstracts, three of which are ACG Presidential Poster Award recipients.

15 Oct 2010

FibroGen announces initiation of FG-3019 phase 2 study for reversing liver fibrosis

FibroGen, Inc. today announced initiation of a phase 2 study to compare the efficacy of FG-3019, a human monoclonal antibody against connective tissue growth factor (CTGF), with placebo in reversing liver fibrosis (scarring of the liver) due to chronic infection with hepatitis B virus (HBV).

15 Oct 2010

Acetadote Injection is now commercially available in Australia

Cumberland Pharmaceuticals Inc. and Phebra Pty Ltd. today announced that Acetadote (acetylcysteine) Injection, an injectable product used to treat acetaminophen (paracetamol) overdose, is now commercially available in the Australian market. Phebra Pty Ltd., an Australian-based specialty pharmaceutical company, has an exclusive license from U.S.-based Cumberland Pharmaceuticals to market and distribute the product in Australia.

15 Oct 2010

NinePoint announces completion of $33 million Series A financing

NinePoint Medical, Inc., an emerging leader in the development of in vivo pathology devices, today announced it has completed a $33 million Series A financing led by Third Rock Ventures and Prospect Venture Partners. The company also announced the establishment of its corporate headquarters in Cambridge, Mass. where Charles Carignan, M.D., serves as president and chief executive officer.

14 Oct 2010

AGA's new book offers strategies to reduce IBS symptoms

A new book from the American Gastroenterological Association (AGA) offers patients with irritable bowel syndrome (IBS) a variety of strategies to lessen the burden that IBS puts on their everyday lives. IBS is a common disorder of the intestines that leads to crampy pain, gassiness, bloating and changes in bowel habits; there is no cure. The new book, "Master Your IBS," includes a variety of strategies to help patients learn how to manage their IBS symptoms and achieve greater freedom from IBS.

14 Oct 2010

Medical Exchange announces next generation of continuing medical education events

Medical Exchange, an innovative provider of medical education solutions for the health care industry, today announced the next generation of continuing medical education events with the launch of collaborativeCARE Conference (C3).

13 Oct 2010

MTN-007 phase trial evaluates vaginal microbicide to prevent rectal transmission of HIV

Tenofovir gel, a vaginal microbicide that has shown promise for preventing HIV through vaginal sex, is being tested in a new trial looking at its safety and acceptability when used rectally. The results of the study, being led by the U.S. National Institutes of Health (NIH)-funded Microbicide Trials Network (MTN), will help determine if the gel should be evaluated further for its potential to prevent HIV among both men and women who engage in receptive anal intercourse.

13 Oct 2010

Magnetecs announces commencement of human studies using CGCI system in patients with arrhythmia

Magnetecs Corporation, a designer and manufacturer of robotic systems for minimally invasive surgical procedures, today reported that human studies have commenced using the Company's Catheter Guidance Control and Imaging (CGCI) system for patients with arrhythmia, or irregular heart beat.

12 Oct 2010

Apollo completes first clinical case with FlexShears Endoscopic device

Apollo Endosurgery, Inc. announced completion of the first clinical case involving its FlexShears Endoscopic Scissors. The new device was used to cut and remove an obstructing eroded suture from the patient's GI tract in a procedure that embodies the Apollo vision of improving patient care with flexible surgery.

12 Oct 2010

Gastroenterology News and Research

Further Reading

Statins reduce risk of colon and rectal cancers: Study

Studies explore impact of upper GI conditions on sleep

Retroflexion in right colon increases yield of polyps in proximal colon

IBD patients with Vitamin D deficiency at greater risk of osteoporosis, osteopenia

Fluticasone gets rid of eosinophils in the esophagus, but does not improve symptoms

Hyperion's HPN-100 granted FDA Fast Track Designation for urea cycle disorders

Preliminary Phase 2 data of TZP-102 for diabetic gastroparesis to be presented at ACG annual meeting

ACG meeting to exhibit Cimzia data for Crohn's disease treatment

Series of pan-endoscopies show unparalleled ability to navigate intestinal tract

Sinai Hospital physician honored at ACG's annual scientific meeting

Heavy drinking during pregnancy associated with serious developmental defects in fetus

Caris Life Sciences presents new diagnostic data at ACG 2010

FibroGen announces initiation of FG-3019 phase 2 study for reversing liver fibrosis

Acetadote Injection is now commercially available in Australia

NinePoint announces completion of $33 million Series A financing

AGA's new book offers strategies to reduce IBS symptoms

Medical Exchange announces next generation of continuing medical education events

MTN-007 phase trial evaluates vaginal microbicide to prevent rectal transmission of HIV

Magnetecs announces commencement of human studies using CGCI system in patients with arrhythmia

Apollo completes first clinical case with FlexShears Endoscopic device

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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